Patents by Inventor William T. Monte

William T. Monte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ready-to-use formulation for Vincristine Sulfate Liposome Injection
    Patent number: 11559486
    Abstract: Disclosed herein are various compositions comprising neoplastic formulations and their methods of use.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: January 24, 2023
    Assignee: Acrotech Biopharma, LLC
    Inventors: William T. Monte, Robert Malcolm Abra, Bing Luo, Yuanpeng Zhang
  • A Ready-to-use Formulation for Vincristine Sulfate Liposome Injection
    Publication number: 20180153805
    Abstract: Disclosed herein are various compositions comprising neoplastic formulations and their methods of use.
    Type: Application
    Filed: July 22, 2016
    Publication date: June 7, 2018
    Inventors: William T. Monte, Robert Malcolm Abra, Bing Luo, Yuanpeng Zhang
  • Method for the preparation of liposome encapsulated vincristine for therapeutic use
    Patent number: 9801874
    Abstract: Improved methods for efficiently constituting liposome encapsulated vincristine for intravenous injection (VSLI) with reduced risk of operational errors and contamination are disclosed.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: October 31, 2017
    Assignees: Spectrum Pharmaceuticals, Tekmira Pharmaceuticals Corporation
    Inventors: William T. Monte, Christopher James Barbosa, Thomas Philip Weber
  • METHOD FOR THE PREPARATION OF LIPOSOME ENCAPSULATED VINCRISTINE FOR THERAPEUTIC USE
    Publication number: 20150290184
    Abstract: Improved methods for efficiently constituting liposome encapsulated vincristine for intravenous injection (VSLI) with reduced risk of operational errors and contamination are disclosed.
    Type: Application
    Filed: November 20, 2013
    Publication date: October 15, 2015
    Inventors: William T. Monte, Christopher James Barbosa, Thomas Philip Weber
  • Process for producing cross-linked polyallylamine hydrochloride
    Patent number: 6525113
    Abstract: The present invention relates to a process for preparing a cross-linked pollyallylamine hydrochloride. The process involves mixing polyallylamine hydrochloride, water, a hydroxide or alkoxide, and a water-miscible organic solvent or co-solvents, to a reaction mixture and adding a cross-linking agent to the reaction mixture to form a cross-linked polyallylamine.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: February 25, 2003
    Assignee: Abbott Laboratories
    Inventors: Russell C. Klix, Jufang H. Barkalow, William T. Monte
  • Process for producing cross-linked polyallylamine hydrochloride
    Publication number: 20010041756
    Abstract: The present invention relates to a process for preparing a cross-linked pollyallylamine hydrochloride. The process involves mixing polyallylamine hydrochloride, water, a hydroxide or alkoxide, and a water-miscible organic solvent or co-solvents, to a reaction mixture and adding a cross-linking agent to the reaction mixture to form a cross-linked polyallylamine.
    Type: Application
    Filed: July 11, 2001
    Publication date: November 15, 2001
    Inventors: Russell C. Klix, Jufang H. Barkalow, William T. Monte
  • Process of protecting a 1,2-aminoalcohol for reductive amination coupling
    Patent number: 5874601
    Abstract: A process of protecting a 1,2- or 1,3-aminoalcohol for reductive amination coupling is provided. The alcohol is protected with trimethylsilyl chloride. Trimethylsilyl protected norepinephrine derivatives useful in the preparation of arbutamine are also provided.
    Type: Grant
    Filed: April 5, 1996
    Date of Patent: February 23, 1999
    Assignee: Abbott Laboratories
    Inventors: William T. Monte, Aline C. Lindbeck
  • Process for making crystalline iron dextran
    Patent number: 5756715
    Abstract: A process for the crystallization of an iron-dextran complex in readily-filterable form comprising adding slowly, with stirring, an acidified aqueous iron-dextran solution to a vessel containing a water miscible organic solvent such as methanol, as well as crystalline iron-dextran complexes so prepared.
    Type: Grant
    Filed: November 8, 1996
    Date of Patent: May 26, 1998
    Assignee: Abbott Laboratories
    Inventors: William T. Monte, Laurie Scaggs
  • Process for the preparation of a protoporphyrin
    Patent number: 5693789
    Abstract: The present invention provides a process for the preparation of BPD 1,4-diene diester A-ring comprising reacting hematoporphyrin IX dimethyl ester with dimethyl acetylenedicarboxylate followed by purification of the product by a series of fractional crystallizations.
    Type: Grant
    Filed: April 10, 1996
    Date of Patent: December 2, 1997
    Assignee: Abbott Laboratories
    Inventors: William T. Monte, Aline C. Lindbeck, Xiu C. Wang, Annette A. Johnston
  • 2,6-disubstituted anilines
    Patent number: 4983772
    Abstract: Novel substituted triazolo [1,5-a]pyrimidine-2-sulfonamides, e.g., 5,7-dimethyl-N-(2,6-dichlorophenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sulf onamide and their agriculturally acceptable salts are prepared. These compounds and compositions containing them are useful for the control of unwanted vegetation. Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonyl chlorides and substituted anilines and their use as intermediates are also described.
    Type: Grant
    Filed: September 13, 1989
    Date of Patent: January 8, 1991
    Assignee: The Dow Chemical Company
    Inventors: William A. Kleschick, Mark J. Costales, Robert J. Ehr, Ben C. Gerwick, III, deceased Meikle, by Diane L. Meikle, executrix, William T. Monte, Norman R. Pearson
  • Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides
    Patent number: 4954163
    Abstract: Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonamides, e.g., 5,7-dimethyl-N-(2,6-dichlorophenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sulf onamide and their agriculturally acceptable salt are prepared. These compounds and compositions containing them are useful for the control of unwanted vegetation. Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonyl chlorides and substituted anilines and their use as intermediates are also described.
    Type: Grant
    Filed: September 13, 1989
    Date of Patent: September 4, 1990
    Assignee: The Dow Chemical Company
    Inventors: William A. Kleschik, Robert J. Ehr, Mark J. Costales, Ben C. Gerwick, III, Richard W. Meikle, deceased, William T. Monte, Norman R. Pearson
  • Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonyl chlorides
    Patent number: 4886883
    Abstract: Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonamides, e.g., 5,7-dimethyl-N-(2,6-dichlorophenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sulf onamide and their agriculturally acceptable salt are prepared. These compounds and compositions containing them are useful for the control of unwanted vegetation. Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonyl chlorides and substituted anilines and their use as intermediates are also described.
    Type: Grant
    Filed: October 21, 1988
    Date of Patent: December 12, 1989
    Assignee: The Dow Chemical Company
    Inventors: William A. Kleschick, Robert J. Ehr, Mark J. Costales, Ben C. Gerwick, III, Richard W. Meikle, deceased, William T. Monte, Norman R. Pearson
  • Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides
    Patent number: 4818273
    Abstract: Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonamides, e.g., 5,7-dimethyl-N-(2,6-dichlorophenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sulf onamide and their agriculturally acceptable salts are prepared. These compounds and compositions containing them are useful for the control of unwanted vegetation. Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonyl chlorides and substituted anilines and their use as intermediates are also described.
    Type: Grant
    Filed: December 10, 1986
    Date of Patent: April 4, 1989
    Assignee: The Dow Chemical Company
    Inventors: William A. Kleschick, Robert J. Ehr, Mark J. Costales, Ben C. Gerwick, III, Richard W. Meikle, deceased, William T. Monte, Pearson, Norman R.
  • Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn
    Patent number: 4755212
    Abstract: Novel compounds, e.g., 5,7-dimethyl-N-(2,6-dichlorolphenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sul fonamide and their compositions and use in the control of weeds and in the suppression of nitrification of ammonium nitrogen in soil. Other novel compounds and their compositions and use in the inhibition of bolting in sugar beets. Other novel compounds and their compositions and use as plant gametocides.
    Type: Grant
    Filed: November 21, 1986
    Date of Patent: July 5, 1988
    Assignee: The Dow Chemical Company
    Inventors: William A. Kleschick, Ben C. Gerwick, III, Robert J. Ehr, William T. Monte, Norman R. Pearson, Richard W. Meikle, Mark J. Costales
  • Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and inhibiting sugar beet bolting
    Patent number: 4741764
    Abstract: Novel compounds, e.g., 5,7-dimethyl-N-(2,6-dichlorolphenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sul fonamide and their compositions and use in the control of weeds and in the suppression of nitrificatin of ammonium nitrogen in soil. Other novel compounds and their compositions and use in the inhibition of bolting in sugar beets. Other novel compounds and their compositions and use as plant gametocides.
    Type: Grant
    Filed: November 21, 1986
    Date of Patent: May 3, 1988
    Assignee: The Dow Chemical Company
    Inventors: William A. Kleschick, Ben C. Gerwick, III, Robert J. Ehr, William T. Monte, Norman R. Pearson, Richard W. Meikle, Mark J. Costales
  • Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil
    Patent number: 4740233
    Abstract: Novel compounds, e.g., 5,7-dimethyl-N-(2,6-dichlorolphenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sul fonamide and their compositions and use in the control of weeds and in the suppression of nitrification of ammonium nitrogen in soil. Other novel compounds and their compositions and use in the inhibition of bolting in sugar beets. Other novel compounds and their compositions and use as plant gametocides.
    Type: Grant
    Filed: November 17, 1986
    Date of Patent: April 26, 1988
    Assignee: The Dow Chemical Company
    Inventors: William A. Kleschick, Robert J. Ehr, Ben C. Gerwick, III, William T. Monte, Norman R. Pearson, Mark J. Costales, Richard W. Meikle
  • Novel sulfonamides and method of making
    Patent number: 4734123
    Abstract: N-aryl-5,6,7-substituted-1,2,4,-triazolo-[1,5-a]pyrimidine-2-sulfonamides undergo oxidative ring cleavage to afford herbicidal substituted N-aryl-5-amino-1,2,4-triazole-3-sulfonamides. These triazolesulfonamides can undergo cyclizations with 1,3-dicarbonyls to form novel herbicidal substituted N-aryl-5,6,7-substituted-1,2,4-triazolo-[1,5-a]pyrimidine-2-sulfonamides.
    Type: Grant
    Filed: May 6, 1986
    Date of Patent: March 29, 1988
    Assignee: The Dow Chemical Company
    Inventor: William T. Monte