Abstract: A washing machine appliance includes a tub and a rotatable basket therein. Methods of operating the washing machine appliance may include, and/or the washing machine appliance may be configured for, measuring a first inertia of a load of articles in the basket by rotating the basket at rotational speeds outside of a resonance speed zone. A water extraction operation is performed after measuring the first inertia of the load of articles. The water extraction operation includes rotating the basket at speeds outside of the resonance speed zone. A second inertia of the load of articles after the water extraction operation is measured by rotating the basket at rotational speeds outside of the resonance speed zone. A load type of the load of articles is determined based on the second inertia. The basket is rotated at speeds within the resonance speed zone only once prior to the water extraction operation.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the cellular entry of hepatitis B virus (HBV) and/or hepatitis D virus (HDV) or interfere with the function of the life cycle of HBV and/or HDV and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV and/or HDV infection. The invention also relates to methods of treating an HBV and/or HDV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: Disclosed are embodiments for providing temperature control for to a temperature-controlled storage compartment in a tunnel of a vehicle. The tunnel extends from a first side of the vehicle, such as the passenger side, to a second side of the vehicle, such as the driver side. The vehicle also includes a refrigeration module that is moveable on a shuttle of the tunnel. The refrigeration module includes a temperature-controlled storage unit configured to open and close in accordance with a path defined by an accessibility assembly. The shuttle transfers power from a power source, such as a battery, to the temperature-controlled storage unit, for example, to provide temperature control even when the vehicle is powered off. Accordingly, the refrigeration module provides a space-efficient system for ensuring prolonged temperature control of items stored in the temperature-controlled storage unit.

Abstract: The present disclosure relates to compositions and methods for reducing expression of MYC gene in a cell. In some embodiments, an expression repressor comprises a targeting moiety that binds a MYC promoter, anchor sequence, or super-enhancer. In some embodiments, the expression repressor comprises an effector moiety that represses transcription or methylates DNA. Systems comprising two expression repressors are also disclosed. The compositions can be used, for example, to treat cancers such as HCC or NSCLC.

Abstract: A method of operation of a texturing/shading unit in a GPU pipeline is used for efficient convolution operations. The method uses texture hardware to collectively fetch all the texels required to calculate properties for a group of output pixels without any duplication. The method then bypasses bilinear filter hardware in the texture hardware and passes the fetched and unfiltered texel data from the texture hardware unit to shader hardware in the texturing/shading unit. The shader hardware uses the fetched texel data to perform a plurality of convolution operations to calculate the properties of each of the output pixel.

Abstract: An apparatus can include a door. The door can be configured to couple with a side of a vehicle. The door can include a step. The door can move the step.

Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.

Abstract: An additive manufacturing apparatus can include a stage configured to hold one or more cured layers of resin that form a component. A radiant energy device can be operable to generate and project radiant energy in a patterned image. An actuator can be configured to change a relative position of the stage relative to the radiant energy device. A reclamation system can be downstream of the stage and can be configured to remove at least a portion of the resin from a resin support. The reclamation system can include a first collection structure configured to accept a resin support therethrough along a resin support movement direction. A first scraper is positioned within the first collection structure. The first scraper has an elongation axis that is offset from the resin support movement direction by an offset angle that is less than 90 degrees.

Abstract: A recoil device is provided for a gun having a barrel with a breech. The device includes a breech nut, a brake assembly, a pneumatic spring and a counter-recoil buffer. The breech nut has first and second adjacent sides. The brake assembly includes a brake cylinder that mounts to the breech nut on the first side. The pneumatic spring mounts to the breech nut on the second side. The counter-recoil buffer attaches to the pneumatic spring. The brake cylinder and the pneumatic spring internally push fluids for recoil absorption and return in response to firing the gun.

Abstract: A therapeutic ultrasound method configured to adaptively transmit ultrasound pulses toward microbubbles in a treatment region to remove an occlusion is described. In some examples, the system may include a treatment pulse unit configured to transmit an ultrasound pulse to a treatment region of a subject, the treatment region including a plurality of microbubbles. An echo detection unit may be configured to receive one or more echoes responsive to the ultrasound pulse. In some examples, the method may also include a data processor configured to identify, using data associated with the echoes, at least one echo signature indicative of a dynamic state of the microbubbles in response to the ultrasound pulse. A controller may be configured to adjust one or more parameters of an additional ultrasound pulse transmitted to the treatment region via the treatment pulse unit based on the at least one echo signature.

Abstract: A system for remotely operating a machine, such as a mine vehicle, includes at least one first emitter for emitting a first signal corresponding to a first zone adjacent to the machine. A transmitter is provided for receiving the first signal emitted by the emitter, the transmitter being adapted for issuing commands for controlling the machine and also indicating the presence of the transmitter in the first zone. A controller is also provided for controlling the machine based on the control signals from the transmitter based on the presence of the transmitter in the first zone. Related methods are also disclosed.

Abstract: Systems and methods are provided for a digital beamformed phased array feed. The system may include a radome configured to allow electromagnetic waves to propagate; a multi-band software defined antenna array tile; a power and clock management subsystem configured to manage power and time of operation; a thermal management subsystem configured to dissipate heat generated by the multi-band software defined antenna array tile; and an enclosure assembly. The multi-band software defined antenna array tile may include a plurality of coupled dipole array antenna elements; a plurality of frequency converters; and a plurality of digital beamformers.

Abstract: Systems and methods for product imaging and provisioning include a mobile application (app) installed on an imaging device, where the mobile app activates the imaging device to generate an image of a product tag associated with an unavailable product at a first location. The mobile app determines, based on the image, a product indicator associated with the unavailable product. A provisioning app, executing on a remote device, receives the product indicator associated with the unavailable product. The provisioning app also receives a user indicator associated with a first user and executes one or more product provisioning rules that determine, based on a product availability database and the user indicator, an availability result. The availability result indicates whether the unavailable product will be available to the first user. The provisioning app is further operable to send the availability result to the imaging device for presentation by the imaging device.

Abstract: An additive manufacturing apparatus can include a stage configured to hold a component formed by one or more layers of resin. A support plate can be positioned above the stage. A radiant energy device can be positioned above the stage. The radiant energy device can be operable to generate and project energy in a predetermined pattern. A feed module can be configured to operably couple with a first end portion of a resin support and can be positioned upstream of the stage. A take-up module can be configured to operably couple with a second end portion of the resin support and can be positioned downstream of the stage.

Abstract: A faceplate of a showerhead has a bottom side that faces a plasma generation region and a top side that faces a plenum into which a process gas is supplied during operation of a substrate processing system. The faceplate includes apertures formed through the bottom side and openings formed through the top side. Each of the apertures is formed to extend through a portion of an overall thickness of the faceplate to intersect with at least one of the openings to form a corresponding flow path for process gas through the faceplate. Each of the apertures has a cross-section that has a hollow cathode discharge suppression dimension in at least one direction. Each of the openings has a cross-section that has a smallest cross-sectional dimension that is greater than the hollow cathode discharge suppression dimension.

Abstract: An appliance is provided including a fluid flow path and a filter receiving portion. The filter receiving portion comprises an installation assistance feature and is configured to receive a water filter such that it is fluidly connected to the flow path. One or more water filter sensors are included that sense when the water filter is in a first position relative to the filter receiving portion so as to enable initiation of an installation procedure to cause the water filter to move to the installed position. The installation procedure utilizes no the installation assistance feature. At least one controller is provided that receives an indication that the water filter is in a first position and causes, based on the indication, activation of the installation assistance feature to reposition the water filter from the first position towards the installed position.

Abstract: A gas turbine engine having a waste heat recovery system is provided. The gas turbine engine includes a compressor section, a combustion section, a turbine section, and an exhaust section in serial flow order and together defining a core air flowpath, the exhaust section including a primary exhaust flowpath and a waste heat recovery flowpath parallel to the primary exhaust flowpath; and the waste heat recovery system includes a heat source exchanger positioned in thermal communication with a first portion of the waste heat recovery flowpath.

Abstract: A search engine system generally includes a user interface in a computing environment configured to receive at least a first fragment from a user and a content display module configured to automatically generate an anticipated search result in the computing environment based on at least the first fragment. The content display module is configured to automatically display search results that include an arrangement of a plurality of visual content elements based on the anticipated search result. The content display module is configured to direct the user to content at one of a network and a local destination associated with one of the visual content elements selectable by the user with the user interface.

Abstract: Provided are compositions comprising compounds or precursors to compounds which may be used for a variety of therapeutic applications including, for example, treating and/or preventing a disease or disorder related to reduced or inadequate mitochondrial activity, including aging or stress, diabetes, obesity, and neurodegenerative diseases. The compounds relate generally to urolithins and precursors thereof, including but not limited to ellagitannins and urolithin A. In certain embodiments the compositions are presented in or as food products or nutritional supplements. These same compounds and compositions can also be used advantageously in generally healthy individuals to increase or maintain metabolic rate, decrease percent body fat, increase or maintain muscle mass, manage body weight, improve or maintain mental performance (including memory), improve or maintain muscle performance, improve or maintain mood, and manage stress.