Patents by Inventor William Volcheck

William Volcheck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10100198
    Abstract: The present invention provides novel compounds and methods for hydrocyanines derived from near-infrared cyanine dyes, as reactive oxygen species probes in imaging. In certain embodiments, the present invention provides reduced dyes as substrates for ELISA and Western blots.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: October 16, 2018
    Assignee: LI-COR, INC.
    Inventors: Kousik Kundu, Nisha Padhye, William Volcheck
  • Publication number: 20170130050
    Abstract: The present invention provides novel compounds and methods for hydrocyanines derived from near-infrared cyanine dyes, as reactive oxygen species probes in imaging. In certain embodiments, the present invention provides reduced dyes as substrates for ELISA and Western blots.
    Type: Application
    Filed: September 7, 2016
    Publication date: May 11, 2017
    Applicant: LI-COR, Inc.
    Inventors: Kousik Kundu, Nisha Padhye, William Volcheck
  • Patent number: 9470691
    Abstract: The present invention provides novel compounds and methods for hydrocyanines derived from near-infrared cyanine dyes, as reactive oxygen species probes in imaging. In certain embodiments, the present invention provides reduced dyes as substrates for ELISA and Western blots.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: October 18, 2016
    Assignee: LI-COR, Inc.
    Inventors: Kousik Kundu, Nisha Padhye, William Volcheck
  • Publication number: 20140213473
    Abstract: The present invention provides novel compounds and methods for hydrocyanines derived from near-infrared cyanine dyes, as reactive oxygen species probes in imaging. In certain embodiments, the present invention provides reduced dyes as substrates for ELISA and Western blots.
    Type: Application
    Filed: February 27, 2014
    Publication date: July 31, 2014
    Inventors: Kousik Kundu, Nisha Padhye, William Volcheck
  • Publication number: 20070042398
    Abstract: The present invention provides for cyanine dyes as near IR quenchers. The cyanine dyes have absorption wavelengths in the near-infrared region of about 650-900 nm and are essentially non-fluorescent. The dyes of the invention have at least one linking group. The present invention also provides substantially non-fluorescent, NIR probes. Biological assays based on these novel, substantially non-fluorescent, NIR probes are also provided.
    Type: Application
    Filed: June 12, 2006
    Publication date: February 22, 2007
    Applicant: LI-COR, INC.
    Inventors: Xinzhan Peng, Xinshe Xu, Daniel Draney, Garrick Little, Jiyan Chen, William Volcheck, Charles Prescott
  • Publication number: 20060280688
    Abstract: Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence.
    Type: Application
    Filed: May 19, 2006
    Publication date: December 14, 2006
    Applicant: LI-COR, Inc.
    Inventors: Joy Kovar, Jiyan Chen, Daniel Draney, D. Olive, William Volcheck, Xinshe Xu, Ananda Lugade, Narasimhachari Narayanan