Abstract: Provided is a method and system to predict a sleep apnea event based upon a sequence of sleep events and mitigate the deleterious effects such an event may have on a person. Some embodiments receive a sequence of sleep events from sensors taking physiological measurements of a person sleeping. These sleep events are compared against grouped sleep apnea events previously gathered from other sleepers with a similar sleep architecture to predict if the person is likely to have a sleep apnea event within an apnea prediction window. If a similar pattern is found, the method sends a sleep apnea warning event responsive to the requested comparison indicating that the person sleeping is likely to experience an imminent sleep apnea event. Various types of sleep entrainment operations may be performed to rouse the person from the sleep to sufficiently to mitigate potential harm from the imminent sleep apnea event.