Patents by Inventor William Z. McCarthy

William Z. McCarthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recovery and purification of 1,1,2-trichloroethane for reuse in the production of ioversol
    Patent number: 5396003
    Abstract: A process for the recovery and purification of 1,1,2-trichloroethane from the intermediates produced for the production of ioversol for reuse thereof.
    Type: Grant
    Filed: May 27, 1993
    Date of Patent: March 7, 1995
    Assignee: Mallinckrodt Medical PMC
    Inventor: William Z. McCarthy
  • Synthesis of ioversol using a minimal excess of acetoxyacetylchloride
    Patent number: 5371278
    Abstract: The use of a minimal excess of acetoxyacetylchloride as a reagent in the synthesis of N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxy-ethyl)glycolamido-2,4,6-triio doisophthalamide.
    Type: Grant
    Filed: March 25, 1994
    Date of Patent: December 6, 1994
    Assignee: Mallinckrodt Medical PMC
    Inventors: William Z. McCarthy, Mills T. Kneller, Youlin Lin, Rebecca A. Wallace, David H. White
  • Separation of high boiling point solvents from amyl acetate
    Patent number: 5356520
    Abstract: A process for the separation of amyl acetate, a high boiling point solvent from various high boiling point corrosive impurities, namely, bromoethyl acetate, in an industrial setting to allow for reuse through continuous recycling thereof.
    Type: Grant
    Filed: February 26, 1993
    Date of Patent: October 18, 1994
    Assignee: Mallinckrodt Medical PMC
    Inventors: William Z. McCarthy, Michael J. Gentilcore
  • Use of azeotropic distillation in process to dry 5-amino-N,N'bis (2,3-dihydroxypropyl)-2,4,6-triiodoisphthalamide
    Patent number: 5256393
    Abstract: The use of azeotropic distillation to dry 5-amino-N,N'bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, an intermediate in the production of N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxyethyl)glycolamido-2,4,6-triiod oisophthalamide.
    Type: Grant
    Filed: April 16, 1991
    Date of Patent: October 26, 1993
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: William Z. McCarthy, Mills T. Kneller, Youlin Lin, David H. White
  • Synthesis of ioversol using chloroacetyl chloride
    Patent number: 5177261
    Abstract: The use of chloroacetylchloride as an alternative or substitute reagent for acetoxychloride in the synthesis of N,N'- bis (2,3-dihydroxypropyl)-5-N-(2-hydroxyethyl)glycolamido-2,4,6-triiodoisophth alamide.
    Type: Grant
    Filed: July 22, 1991
    Date of Patent: January 5, 1993
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: William Z. McCarthy, Mills T. Kneller, Youlin Lin, David H. White
  • Process for production of ioversol
    Patent number: 4997983
    Abstract: A process for the production of N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxyethyl)glycolamido-2,4,6-triiod oisopht alamide wherein a mixture of 1,1,2-trichloroethane and 5-[(N-(2-acetoxyethyl)acetoxyacetamido]N,N'-bis(2,3-diacetoxypropyl)-2,4,6 -triiodoisophthalamide (hexaacetate) is distilled to remove 1,1,2-trichloroethane, at least a part of which is distilled as an azeotrope with water, so that a solvent exchange is effected to produce a mixture of hexaacetate in water. Hydrolysis of hexaacetate produces the desired product.
    Type: Grant
    Filed: January 31, 1990
    Date of Patent: March 5, 1991
    Assignee: Mallinckrodt, Inc.
    Inventor: William Z. McCarthy