Patents by Inventor Win-Chin Chiang

Win-Chin Chiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of improving tolerance to hypoallergenic infant formulas
    Patent number: 11412768
    Abstract: The present invention relates to a method of improving tolerance to hypoallergenic infant formulas. The method comprises neutralizing the pH of infant formulas containing ingredients exhibiting fishy, sour, or beany characteristics.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: August 16, 2022
    Assignee: Mead Johnson Nutrition Company
    Inventors: Khaled A Khatib, Win-Chin Chiang, Jane Ehninger
  • Oxidative modification improves the drugability of cell penetrating peptides as drug carriers
    Patent number: 10526369
    Abstract: The present invention provides a cell penetrating peptide dimer by oxidative modification, in which each monomer is connected with each other by the disulfide linkage. The drugability of the peptide dimer has been improved through enhancing stability, reducing proteolysis, retaining permeability and increasing heparan sulfate binding specificity. The modified peptide products can be used to deliver drug molecules as a suitable drug carrier for targeted therapy.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: January 7, 2020
    Inventors: Yu-Min Lin, Wei-Chen Chen, Win-Chin Chiang, Ting Lian Chang, Chun-Hung Kuo
  • OXIDATIVE MODIFICATION IMPROVES THE DRUGABILITY OF CELL PENETRATING PEPTIDES AS DRUG CARRIERS
    Publication number: 20180105556
    Abstract: The present invention provides a cell penetrating peptide dimer by oxidative modification, in which each monomer is connected with each other by the disulfide linkage. The drugability of the peptide dimer has been improved through enhancing stability, reducing proteolysis, retaining permeability and increasing heparan sulfate binding specificity. The modified peptide products can be used to deliver drug molecules as a suitable drug carrier for targeted therapy.
    Type: Application
    Filed: April 6, 2017
    Publication date: April 19, 2018
    Applicant: JOWIN BIOPHARMA
    Inventors: YU-MIN LIN, WEI-CHEN CHEN, WIN-CHIN CHIANG, TING LIAN CHANG, CHUN-HUNG KUO
  • METHOD OF IMPROVING TOLERANCE TO HYPOALLERGENIC INFANT FORMULAS
    Publication number: 20160255869
    Abstract: The present invention relates to a method of improving tolerance to hypoallergenic infant formulas. The method comprises neutralizing the pH of infant formulas containing ingredients exhibiting fishy, sour, or beany characteristics.
    Type: Application
    Filed: September 3, 2015
    Publication date: September 8, 2016
    Inventors: Khaled A Khatib, Win-Chin Chiang, Jane Ehninger
  • EXTRACTS OF PERILLA FRUTESCENS SEEDS AND THEIR PHARMACEUTICAL USES
    Publication number: 20150224159
    Abstract: Disclosed is an extract of Perilla frutescens seeds that contains rosmarinic acid, luteolin, and apigenin, the weight ratio between rosmarinic acid, luteolin, and apigenin being 0.1-200:0.1-200:1. Also disclosed is a method for treating a psychiatric disorder using the above-described extract or an extract of Perilla frutescens seeds containing at least an active agent selected from the group consisting of rosmarinic acid, luteolin, and apigenin.
    Type: Application
    Filed: February 3, 2015
    Publication date: August 13, 2015
    Inventors: Leah Lo, Win-Chin Chiang, Jui-Ching Chen, Yu-Min Lin, Chien-Chang Wu, Che-Yi Lin, Chien-Jen Shih, Yu-Hsuan Lin, Tzu-Chun Chen, Yu-Hsiang Huang
  • AMINO ACID-BASED NUTRITIONAL FORMULATIONS
    Publication number: 20140205712
    Abstract: The present invention relates to an amino acid-based nutritional formulation comprising, per 100 g total amino acids, between about 4.5 and about 5 g glutamate. The ratio of cysteine:methionine is in the range of about 0.9:1 to about 1:1.2. The nutritional formulation may also comprise a lipid source, a carbohydrate source, an emulsifier comprising CITREM or DATEM, and amino acids, wherein glutamate is present in an amount of between about 4.
    Type: Application
    Filed: March 26, 2014
    Publication date: July 24, 2014
    Inventors: Joshua C. Anthony, Robert A. Burns, Yung-Hsiung Lee, Win-Chin Chiang, Khaled A. Khatib, John R. Euber, John R. Reckelhoff
  • Amino acid-based nutritional formulations
    Patent number: 8722120
    Abstract: The present invention relates to an amino acid-based nutritional formulation comprising, per 100 g total amino acids, between about 4.5 and about 5 g glutamate. The ratio of cysteine:methionine is in the range of about 0.9:1 to about 1:1.2. The nutritional formulation may also comprise a lipid source, a carbohydrate source, an emulsifier comprising CITREM or DATEM, and amino acids, wherein glutamate is present in an amount of between about 4.5 and about 5 g per 100 g total amino acids.
    Type: Grant
    Filed: August 2, 2006
    Date of Patent: May 13, 2014
    Assignee: Mead Johnson Nutrition Company
    Inventors: Joshua C. Anthony, Robert A. Burns, Yung H. Lee, Win-Chin Chiang, Khaled A. Khatib, John R. Euber, John R. Reckelhoff
  • NUTRITIONAL FORMULA CONTAINING OCTENYL SUCCINATE ANHYDRIDE-MODIFIED TAPIOCA STARCH
    Publication number: 20120064220
    Abstract: The present invention relates to a nutritional formulation comprising a lipid source, a carbohydrate source, a protein equivalent source, and an emulsifying agent comprising OSA-modified tapioca starch which contains less than about 0.05% non-protein nitrogen.
    Type: Application
    Filed: September 9, 2011
    Publication date: March 15, 2012
    Applicant: Mead Johnson Nutrition Company
    Inventors: Khaled A. Khatib, Win-Chin Chiang, Rosanne P. Batema
  • Nutritional composition with improved digestibility
    Patent number: 8075934
    Abstract: The present invention is directed an improved nutritional composition, methods of improving digestion, and methods of enhancing the bioavailability of TGF-?.
    Type: Grant
    Filed: February 13, 2009
    Date of Patent: December 13, 2011
    Assignee: Mead Johnson Nutrition Company
    Inventors: Dattatreya Banavara, Win-Chin Chiang, Deborah A. Schade, Joaquin A. Franco, Juan M. Gonzalez, Dirk Hondmann, Zeina E. Jouni, Yung-Hsiung Lee, Robert J. McMahon, Kristin Morris, Deshanie Rai, Gyan P. Rai, Nagendra Rangavajla, Francisco J. Rosales, William Michael Russell, Eric Van Tol, Hugh N. Tucker, Donald Carey Walker
  • Nutritional Composition With Improved Digestibility
    Publication number: 20100104696
    Abstract: The present invention is directed an improved nutritional composition, methods of improving digestion, and methods of enhancing the bioavailability of TGF-?.
    Type: Application
    Filed: February 13, 2009
    Publication date: April 29, 2010
    Applicant: Mead Johnson & Co.
    Inventors: Dattatreya Banavara, Win-Chin Chiang, Deborah A. Schade, Joaquin A. Franco, Juan M. Gonzalez, Dirk Hondmann, Zeina E. Jouni, Yung-Hsiung Lee, Robert J. McMahon, Kristin Morris, Deshanie Rai, Gyan P. Rai, Nagendra Rangavajla, Francisco J. Rosales, William Michael Russell, Eric Van Tol, Hugh N. Tucker, Donald Carey Walker
  • Low-lactose partially hydrolyzed infant formula
    Patent number: 7618669
    Abstract: The present invention relates to a low-lactose, partially hydrolyzed infant formula. The carbohydrate component of the infant formula comprises between 0% and 60% lactose and the protein component of the infant formula comprises partially hydrolyzed whey protein and casein, the protein component having a particular molecular weight.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: November 17, 2009
    Assignee: Mead Johnson Nutrition Company
    Inventors: Nagendra Rangavajla, Win-Chin Chiang, Khaled A. Khatib, David A. Wynsen, Gabor Puski, Jon Vanderhoof, Robert A. Burns
  • METHOD FOR DECREASING BITTERNESS AND IMPROVING TASTE OF PROTEIN-FREE AND HYDROLYZED INFANT FORMULAS
    Publication number: 20090117256
    Abstract: The present invention relates to a method for decreasing the bitterness or improving the taste of a protein-free or hydrolyzed infant formula. The method comprises intermixing ingredients of the formula and adjusting the pH of the formula to between about 6.5 and about 7.2.
    Type: Application
    Filed: October 20, 2008
    Publication date: May 7, 2009
    Inventors: Khaled A. Khatib, Win-Chin Chiang, Jane Ehninger
  • Method for blending heat-sensitive material using a conical screw blender with gas injection
    Patent number: 7387427
    Abstract: The invention relates to a conical screw blender which comprises an inverted cone-shaped vessel. The blender also includes a material inlet, a material outlet, a driven screw housed within the vessel, and at least two non-diffuse gas injection lines attached to the vessel. The conical screw blender of the present invention can be used not only for the mixing of materials, but also for the drying of materials.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: June 17, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Win-Chin Chiang, Nagendra Rangavajla
  • Method for extending the shelf-life of powdered nutritional formulations which contain viable probiotics
    Publication number: 20080095752
    Abstract: The invention involves a method for extending the shelf life of a powdered nutritional formulation that contains LGG by reducing and maintaining a threshold water activity or moisture content in the powdered LGG-containing formulation.
    Type: Application
    Filed: October 20, 2006
    Publication date: April 24, 2008
    Inventors: Win-Chin Chiang, Bryon W. Petschow, Adrie Baars, Yung H. Lee, Luis Jose Montelongo, Nagendra Rangavajla
  • Conical screw blender
    Publication number: 20080094934
    Abstract: The invention relates to a conical screw blender which comprises an inverted cone-shaped vessel. The blender also includes a material inlet, a material outlet, a driven screw housed within the vessel, and at least two non-diffuse gas injection lines attached to the vessel. The conical screw blender of the present invention can be used not only for the mixing of materials, but also for the drying of materials.
    Type: Application
    Filed: October 20, 2006
    Publication date: April 24, 2008
    Inventors: Win-Chin Chiang, Nagendra Rangavajla
  • Amino acid-based nutritional formulations
    Publication number: 20080032002
    Abstract: The present invention relates to an amino acid-based nutritional formulation comprising, per 100 g total amino acids, between about 4.5 and about 5 g glutamate. The ratio of cysteine:methionine is in the range of about 0.9:1 to about 1:1.2. The nutritional formulation may also comprise a lipid source, a carbohydrate source, an emulsifier comprising CITREM or DATEM, and amino acids, wherein glutamate is present in an amount of between about 4.5 and about 5 g per 100 g total amino acids.
    Type: Application
    Filed: August 2, 2006
    Publication date: February 7, 2008
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Joshua C. Anthony, Robert A. Burns, Yung H. Lee, Win-Chin Chiang, Khaled A. Khatib, John R. Euber, John R. Reckelhoff
  • Nutritional formulations containing octenyl succinate anhydride-modified tapioca starch
    Publication number: 20080026105
    Abstract: The present invention relates to a nutritional formulation comprising a lipid source, a carbohydrate source, a protein equivalent source, and an emulsifying agent comprising OSA-modified tapioca starch which contains less than about 0.05% non-protein nitrogen.
    Type: Application
    Filed: July 28, 2006
    Publication date: January 31, 2008
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Khaled A. Khatib, Win-Chin Chiang, Rosanne P. Batema
  • Methods for producing protein partial hydrolysates and infant formulas containing the same
    Publication number: 20060286208
    Abstract: The present invention relates to a process for preparing a protein partial hydrolysate. The process involves intermixing a solution of whey protein, casein and water; adjusting the temperature and pH of the solution, adding Protease N to the solution, and allowing the solution to hydrolyze for a period of time so as to obtain a degree of hydrolysis between about 4% and 10%. The hydrolysis is ended by subjecting the solution to enzyme deactivation.
    Type: Application
    Filed: June 1, 2005
    Publication date: December 21, 2006
    Inventors: Nagendra Rangavajla, Win-Chin Chiang, Lily Kelly, Debra Nichols
  • Low-lactose partially hydrolyzed infant formula
    Publication number: 20060286252
    Abstract: The present invention relates to a low-lactose, partially hydrolyzed infant formula. The carbohydrate component of the infant formula comprises between 0% and 60% lactose and the protein component of the infant formula comprises partially hydrolyzed whey protein and casein, the protein component having a particular molecular weight.
    Type: Application
    Filed: June 1, 2005
    Publication date: December 21, 2006
    Inventors: Nagendra Rangavajla, Win-Chin Chiang, Khaled Khatib, David Wynsen, Gabor Puski, Jon Vanderhoof, Robert Burns
  • Process of displacement washing in a centrifuge filter
    Patent number: 5300233
    Abstract: Displacement washing of slurry body is provided in a centrifuge filter (peeler centrifuge) by introducing wash liquid along the inner surface of the drum while the drum is rotating. The wash liquid moves through the filter into the slurry body in a broad front to displace the mother liquor of the slurry body toward the axis of rotation of the drum. The mother liquor is removed by an overflow pipe or dip tube to a point outside the centrifuge filter for disposal.
    Type: Grant
    Filed: February 9, 1993
    Date of Patent: April 5, 1994
    Assignee: Dorr-Oliver Incorporated
    Inventors: Chie-Ying Lee, Win-Chin Chiang