Abstract: The invention relates to an intravaginal monitoring device, method of intravaginal monitoring, and system and network for intravaginal monitoring. The intravaginal monitoring device and or network includes multiple modes of operation that enable non-pregnancy monitoring, pregnancy testing, pregnancy monitoring, STD detection, precancerous condition monitoring, cancerous condition monitoring, pre-birth monitoring and prediction, neo-natal monitoring, ovulation monitoring, an automated rhythm method, among various applications of the device, method and network of the present invention.

Abstract: The invention generally relates to intravaginal monitoring devices, supporting networks, web services, billing services, modes of operation of the devices and networks, and processing of data harvested by an intravaginal device and communication to the network. Methods, systems and networks for advertising are provided herein.

Abstract: Various types of intravaginal monitoring devices (IMD) along with various supporting medical and computing devices within a communication network service pluralities of femal reproductive systems An IMD alone or with assistance from one or more supporting systems assists in detection, monitoring, therapy delivery and efficacy evaluations of various types of physiologic conditions of the various femal reproductive systems Exemplary conditions include those related to pregnancy, premature birth, fertility, ovulation, diseases, infections, fluids, flora, pre-cancerous conditions, cancer, non-human animal estrus, etc Various types of IMDs include those with multiple sensors within a housing sized for at least partial insertion into a vaginal channel of a reproductive system In some IMDs, only a single sensor such as an optical imager might be found, while in others multiple such imagers and as temperature, pH, glucose, electrolyte, sonogram, magnetic resonance, pressure, ultrasound, microphone, etc, sensors can a

Abstract: The invention relates to an intravaginal monitoring device, method of intravaginal monitoring, and system and network for intravaginal monitoring. The intravaginal monitoring device and or network includes multiple modes of operation that enable non-pregnancy monitoring, pregnancy testing, pregnancy monitoring, STD detection, precancerous condition monitoring, cancerous condition monitoring, pre-birth monitoring and prediction, neo-natal monitoring, ovulation monitoring, an automated rhythm method, among various applications of the device, method and network of the present invention.

Abstract: The invention generally relates to intravaginal monitoring devices, supporting networks, web services, billing services, modes of operation of the devices and networks, and processing of data harvested by an intravaginal device and communication to the network. Methods, systems and networks for advertising are provided herein.

Abstract: Intravaginal monitoring devices (IMDs) with adjustable optics assemblies support local and remote control of mechanical and electro-mechanical mechanisms associated with multiple imagers and other sensors for tailoring an IMD to meet the specific dimensions and characteristics of various female reproduce systems. Such mechanisms also assist in guiding and analyzing pathways through a vaginal channel to and including a cervix. Exemplary pivoting, rotational, and telescopic infrastructures with integrated, local and remote control and monitoring are supported with external visual displays of images and video streams in devices such as phones, tablet and laptop computers, and servers for use by a patient or any medical support staff. Such multiple images or video streams may be combined to provide an enhanced viewing experience.

Abstract: The present invention relates to an improved process for making commercial quantities of a polypeptide or fragment thereof, e.g. a T-20 or a T-1249 composition, or a fragment of a T-20 or a T-1249 composition. One variant of a T-20 composition is known as Fuzeon™ enfuvirtide. The improvement includes using a low void space resin, a resin made from a copolymer having less than 5% organic extractables, a resin made using a chloride corrosion resistant filter, resin beads functionalized using a nitro-compound, resins made using jetting techniques, and resins made using seed expansion techniques. In yet other variants, the invention provides a composition made using the processes described herein.

Abstract: The invention provides a pharmaceutical composition that includes a non-ionizable anthlemintic drug or derivative thereof loaded onto an anion exchange resin or a cation exchange resin. The non-ionizable anthlemintic is praziquantel, a praziquantel derivative, epsiprantel, or an epsiprantel derivative. The anthlemintic can also include Droncit, a derivative of Droncit, a precursor of Droncit, Drontal, a precursor of Drontal, a derivative of Drontal, Drontal Plus, a derivative of Drontal Plus, a precursor of Drontal Plus, a formulation comprising Praziquantel and Pyrantel Pamoate, and a formulation comprising Praziquantel, Pyrantel Pamoate and/or Febantel. In another variant, the invention includes a pharmaceutical composition including a basic anthlemintic drug loaded onto an anion exchange resin, or an acidic anthlemintic drug loaded onto a cation exchange resin, and a process for manufacturing the pharmaceutical composition.

Abstract: The present invention relates to a process for making a biologically active substance or therapeutic agent free of a chlorotrityl chloride linker-resin. The process includes reacting an activated amino acid or activated amino acid derivative with a substituted or unsubstituted trityl alcohol resin to obtain a resin-CT-AA product; and, reacting the resin-CT-AA product with other building blocks of the biologically active substance or therapeutic agent to obtain said biologically active substance or therapeutic. A product created by this process is also provided herein. The invention is particularly useful to create T-20 and T-1249 therapeutics.