Patents by Inventor Wojciech Czaja

Wojciech Czaja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11965888
    Abstract: Disclosed herein are methods for quantifying total endotoxin load in a biofilm sample. Also provided are methods for identifying a gram-negative biofilm derived bacterial infection. The disclosed methods more accurately define actual total endotoxin levels and can detect the presence of endotoxin in a given biofilm volume at a higher resolution than current extraction techniques.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: April 23, 2024
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Erica Shwarz, Wojciech Czaja
  • Publication number: 20210318314
    Abstract: Disclosed herein are methods for quantifying total endotoxin load in a biofilm sample. Also provided are methods for identifying a gram-negative biofilm derived bacterial infection. The disclosed methods more accurately define actual total endotoxin levels and can detect the presence of endotoxin in a given biofilm volume at a higher resolution than current extraction techniques.
    Type: Application
    Filed: April 6, 2021
    Publication date: October 14, 2021
    Inventors: Erica Shwarz, Wojciech Czaja
  • Publication number: 20200325600
    Abstract: The present disclosure is directed to an oil-infused bacterial nanocellulose (BNC) material including a porous body comprising a three-dimensional network of bacterial nanocellulose fibers defining a plurality of interconnected pores; and, an oil infused within the plurality of pores. The present disclosure additionally describes a method of preparing an oil-infused BNC material that includes fermenting bacteria to form a porous body of bacterial nanocellulose fibers having a three-dimensional network defining a plurality of interconnected pores; mechanically pressing the porous body; dehydrating the porous body; and infusing the porous body with an oil infusion fluid including an oil so as to entrap the oil in the pores of the porous body forming an oil-infused BNC material.
    Type: Application
    Filed: April 9, 2020
    Publication date: October 15, 2020
    Inventors: Wojciech Czaja, Erica Shwarz, Darric Inselman
  • Patent number: 10802098
    Abstract: An approach is presented to recontruct image data for an object using a partial set of magnetic resonance (MR) measurements. A subset of data points in a data space representing an object are selected (e.g. through random sampling) for MR data acquisition. Partial MR data corresponding to the subset of data points is received and used for image reconstruction. The overall speed of image reconstruction can be reduced dramatically by relying on acquisition of data for the subset of data points rather than for all data points in the data space representing the object. Compressive sensing type arguments are used to fill in missing measurements, using a priori knowledge of the structure of the data. A compressed data matrix can be recovered from measurements that form a tight frame. It can be established that these measurements satisfy the restricted isometry property (RIP). The zeroth-order regularization minimization problem can then be solved, for example, using a 2D ILT approach.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: October 13, 2020
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, University of Maryland, College Park
    Inventors: Peter J. Basser, Ruiliang Bai, Alexander Cloninger, Wojciech Czaja
  • Publication number: 20200233051
    Abstract: An approach is presented to reconstruct image data for an object using a partial set of magnetic resonance (MR) measurements. A subset of data points in a data space representing an object are selected (e.g. through random sampling) for MR data acquisition. Partial MR data corresponding to the subset of data points is received and used for image reconstruction. The overall speed of image reconstruction can be reduced dramatically by relying on acquisition of data for the subset of data points rather than for all data points in the data space representing the object. Compressive sensing type arguments are used to fill in missing measurements, using a priori knowledge of the structure of the data. A compressed data matrix can be recovered from measurements that form a tight frame. It can be established that these measurements satisfy the restricted isometry property (RIP). The zeroth-order regularization minimization problem can then be solved, for example, using a 2D ILT approach.
    Type: Application
    Filed: April 3, 2020
    Publication date: July 23, 2020
    Applicants: The United States of America, as represented by the Secretary, Dept. of Health and Human Services, University of Maryland, College Park
    Inventors: Peter J. Basser, Ruiliang Bai, Alexander Cloninger, Wojciech Czaja
  • Patent number: 10613176
    Abstract: An approach is presented to recontruct image data for an object using a partial set of magnetic resonance (MR) measurements. A subset of data points in a data space representing an object are selected (e.g. through random sampling) for MR data acquisition. Partial MR data corresponding to the subset of data points is received and used for image reconstruction. The overall speed of image reconstruction can be reduced dramatically by relying on acquisition of data for the subset of data points rather than for all data points in the data space representing the object. Compressive sensing type arguments are used to fill in missing measurements, using a priori knowledge of the structure of the data. A compressed data matrix can be recovered from measurements that form a tight frame. It can be established that these measurements satisfy the restricted isometry property (RIP). The zeroth-order regularization minimization problem can then be solved, for example, using a 2D ILT approach.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: April 7, 2020
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, University of Maryland, College Park
    Inventors: Peter J. Basser, Ruiliang Bai, Alexander Cloninger, Wojciech Czaja
  • Publication number: 20170260297
    Abstract: The present disclosure describes an implant for tissue replacement or augmentation including a resorbable non-pyrogenic porous body of irradiated oxidized cellulose, formed from a precursor reactive mixture of irradiated cellulose and an oxidizing agent, where the body forms a heterogeneous three-dimensional fibrillar network.
    Type: Application
    Filed: May 25, 2017
    Publication date: September 14, 2017
    Inventors: Wojciech Czaja, Dmytro D. Kyryliouk
  • Patent number: 9670289
    Abstract: The present disclosure describes an implant for tissue replacement or augmentation including a resorbable non-pyrogenic porous body of irradiated oxidized cellulose, formed from a precursor reactive mixture of irradiated cellulose and an oxidizing agent, where the body forms a heterogeneous three-dimensional fibrillar network. Also disclosed is a method for producing a body of oxidized cellulose including irradiating a body of cellulose to form an irradiated body of cellulose, and reacting the irradiated body of cellulose with an oxidizing agent to form a non-pyrogenic porous and resorbable body of oxidized cellulose.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: June 6, 2017
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Wojciech Czaja, Dmytro D. Kyryliouk
  • Publication number: 20170089995
    Abstract: An approach is presented to recontruct image data for an object using a partial set of magnetic resonance (MR) measurements. A subset of data points in a data space representing an object are selected (e.g. through random sampling) for MR data acquisition. Partial MR data corresponding to the subset of data points is received and used for image reconstruction. The overall speed of image reconstruction can be reduced dramatically by relying on acquisition of data for the subset of data points rather than for all data points in the data space representing the object. Compressive sensing type arguments are used to fill in missing measurements, using a priori knowledge of the structure of the data. A compressed data matrix can be recovered from measurements that form a tight frame. It can be established that these measurements satisfy the restricted isometry property (RIP). The zeroth-order regularization minimization problem can then be solved, for example, using a 2D ILT approach.
    Type: Application
    Filed: April 17, 2015
    Publication date: March 30, 2017
    Applicants: The United States of America, as represented by the Secretary, Department of Health and Human Serv, University of Maryland, College Park
    Inventors: Peter J. Basser, Ruiliang Bai, Alexander Cloninger, Wojciech Czaja
  • Publication number: 20150266978
    Abstract: The present disclosure describes an implant for tissue replacement or augmentation including a resorbable non-pyrogenic porous body of irradiated oxidized cellulose, formed from a precursor reactive mixture of irradiated cellulose and an oxidizing agent, where the body forms a heterogeneous three-dimensional fibrillar network. Also disclosed is a method for producing a body of oxidized cellulose including irradiating a body of cellulose to form an irradiated body of cellulose, and reacting the irradiated body of cellulose with an oxidizing agent to form a non-pyrogenic porous and resorbable body of oxidized cellulose.
    Type: Application
    Filed: June 10, 2015
    Publication date: September 24, 2015
    Inventors: Wojciech Czaja, Dmytro D. Kyryliouk
  • Patent number: 9090713
    Abstract: The present disclosure describes an implant for tissue replacement or augmentation including a resorbable non-pyrogenic porous body of irradiated oxidized cellulose, formed from a precurosr reactive mixture of irradiated cellulose and an oxidizing agent, where the body forms a heterogeneous three-dimensional fibrillar network. Also disclosed is a method for producing a body of oxidized cellulose including irradiating a body of cellulose to form an irradiated body of cellulose, and reacting the irradiated body of cellulose with an oxidizing agent to form a non-pyrogenic porous and resorbable body of oxidized cellulose.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: July 28, 2015
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Wojciech Czaja, Dmytro D. Kyryliouk
  • Patent number: 8951551
    Abstract: The present invention includes compositions and methods for the integration of a non-allergenic nanocellulose into a wound bed. The composition may be formed into a wide variety of implants, e.g., a suture, a sheet, a compress, a bandage, a band, a prosthesis, a fiber, a woven fiber, a bead, a strip, a clasp, a prosthesis, a catheter, a screw, a bone plate, a pin, a bandage or combinations thereof.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: February 10, 2015
    Assignee: Board of Regents, The University of Texas System
    Inventors: R. Malcolm Brown, Jr., Wojciech Czaja, Marc Jeschke, David J. Young
  • Publication number: 20130224278
    Abstract: The present disclosure describes an implant for tissue replacement or augmentation including a resorbable non-pyrogenic porous body of irradiated oxidized cellulose, formed from a precurosr reactive mixture of irradiated cellulose and an oxidizing agent, where the body forms a heterogeneous three-dimensional fibrillar network. Also disclosed is a method for producing a body of oxidized cellulose including irradiating a body of cellulose to form an irradiated body of cellulose, and reacting the irradiated body of cellulose with an oxidizing agent to form a non-pyrogenic porous and resorbable body of oxidized cellulose.
    Type: Application
    Filed: February 22, 2013
    Publication date: August 29, 2013
    Inventors: Wojciech Czaja, Dmytro D. Kyryliouk
  • Publication number: 20070053960
    Abstract: The present invention includes compositions and methods for the integration of a non-allergenic nanocellulose into a wound bed. The composition may be formed into a wide variety of implants, e.g., a suture, a sheet, a compress, a bandage, a band, a prosthesis, a fiber, a woven fiber, a bead, a strip, a clasp, a prosthesis, a catheter, a screw, a bone plate, a pin, a bandage or combinations thereof.
    Type: Application
    Filed: August 31, 2006
    Publication date: March 8, 2007
    Applicant: Board Of Regents, The University Of Texas System
    Inventors: R. Brown, Wojciech Czaja, Marc Jeschke, David Young