Patents by Inventor Wolf-Georg Forssmann

Wolf-Georg Forssmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cardiodilatin fragment, process for preparing same and use thereof
    Patent number: 5449751
    Abstract: Described is a peptide fragment which comprises the amino acid sequence 95-126 of ANF/CDD 1-126 (gamma-hANaP) and is formed in the kidney. The fragment urodilatin (ANF/CDD 95-126) has the following amino acid sequence: ##STR1## wherein R.sup.1 and R.sup.2 each represent further peptide fragments of ANF/CDD 1-126 (gamma-hANaP). In the amino acid sequence R.sup.1 is Thr-Alo-Pro-Arg-Ser-Leu-Arg-Arg-Ser-Ser and R.sup.2 is Asn-Ser-Phe-Arg-Tyr. Further described are processes for the preparation and/or recovery of the new peptide fragment and a medicament containing urodilatin (ANF/CDD 95-126 ) as well as medical indications of the medicament.
    Type: Grant
    Filed: January 24, 1994
    Date of Patent: September 12, 1995
    Assignees: Pharma Bissendorf Peptide GmbH, Wolf-Georg Forssmann
    Inventors: Wolf-Georg Forssmann, Jeanette M. Alt, Gerhard Becker, Franz Herbst
  • Method for determining cardiodilatin and fragments thereof and antibodies useful in determination of cardiodilatin and its fragments
    Patent number: 4895932
    Abstract: This invention teaches a method for determining the hormone cardiodilatin active fragments thereof, well as antibodies thereto.
    Type: Grant
    Filed: August 8, 1988
    Date of Patent: January 23, 1990
    Assignee: Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft m.b.H.
    Inventor: Wolf-Georg Forssmann
  • Human intestinal hormone and its use
    Patent number: 4806336
    Abstract: A human intestinal hormone having the following peptide structure: His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Le u-Gln-Arg-Leu-Gln-Gly-Leu-Val-NH.sub. 2 ; compositions containing such hormone; and a method of stimulating pancreatic secretion.
    Type: Grant
    Filed: November 7, 1986
    Date of Patent: February 21, 1989
    Assignee: KabiGen AB and Skandigen AB
    Inventors: Mats Carlquist, Hans Jornvall, Wolf-Georg Forssmann, Lars Thulin, Catja Johansson, Viktor Mutt
  • Composition containing cordiodilatin or fragments thereof and methods of obtaining cardiodilatin
    Patent number: 4782044
    Abstract: This invention teaches therapeutic compositions containing the hormone cardiodilatin of active fragments thereof, as well as methods for obtaining the cardiodilatin. The compositions are useful in relaxing smooth, blood vessel muscles.
    Type: Grant
    Filed: January 4, 1988
    Date of Patent: November 1, 1988
    Assignee: ORGANON-Medizinisch-Molekularbiologische Forschungsgellschaft m.b.H
    Inventor: Wolf-Georg Forssmann
  • Cardiodilatin, a new peptide hormone and process for its preparation
    Patent number: 4751284
    Abstract: There is described a new peptide hormone (cardiodilatin) and a process for its preparation, with the amino acid sequence: Asn-Pro-Val-Tyr-Gly-Ser-Val-Ser-Asn-Ala-Asp-Leu-Met-Asp-Phe-Lys-Asn-Leu-Le u-Asp-His-Leu-Glu-Asp-Lys-Met-Pro-Leu-Glu-Asp-Glu-Ala-Met-Pro-Pro-Gln-Val-L eu-Ser-Glu-Gln-Asp-Glu-Glu-Val-Gly-Ala-Pro-Leu-Pro-Leu-Leu-Glu-Glu-Val-Pro- Pro-Trp-Thr-Gly-Glu-Val-A n-Pro of the composition Asp/Asn 14, Thr 3, Ser 15, Glu/Gln 12, Pro 10, Gly 12, Ala 10, Val 7, Met 4, Ile 1, Leu 15, Tyr 2, Phe 3, Lys 4, His 2, Arg 10, Trp 2, a molecular weight of 13000 Dalton and an isoelectric point I.P. of 6 to 6.5.The peptide hormone, as well as its C-terminal fragments obtained after partial cyanogen bromide fission between and behind Met groups, possess a high relaxing action on the smooth bloodvessel musculature.
    Type: Grant
    Filed: August 20, 1985
    Date of Patent: June 14, 1988
    Assignee: Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft m.b.H
    Inventor: Wolf-Georg Forssmann