Patents by Inventor Wolfgang Reinhard Ludwig Notz

Wolfgang Reinhard Ludwig Notz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azaindole derivatives
    Patent number: 8835420
    Abstract: Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating immunological disorders, cardiovascular disease, cancer, and other diseases, disorders or conditions associated with PI3K?.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: September 16, 2014
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Wolfgang Reinhard Ludwig Notz, Michael B. Wallace
  • AZAINDOLE DERIVATIVES
    Publication number: 20140018344
    Abstract: Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating immunological disorders, cardiovascular disease, cancer, and other diseases, disorders or conditions associated with PI3K?.
    Type: Application
    Filed: July 8, 2013
    Publication date: January 16, 2014
    Inventors: Edcon Chang, Wolfgang Reinhard Ludwig Notz, Michael B. Wallace
  • HSP90 INHIBITORS
    Publication number: 20120172321
    Abstract: The invention relates to HSP90 inhibiting compounds consisting of the formula: wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: March 1, 2012
    Publication date: July 5, 2012
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Young K. Chen, Erick Co, Prasuna Guntupalli, John D. Lawson, Wolfgang Reinhard Ludwig Notz, Jeffrey A. Stafford, Huong-Thu Ton-Nu
  • HSP90 inhibitors
    Patent number: 8071766
    Abstract: The invention relates to HSP90 inhibiting compounds consisting of the formula: wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: December 6, 2011
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Young K. Chen, Erick Co, Prasuna Guntupalli, John D. Lawson, Wolfgang Reinhard Ludwig Notz, Jeffrey A. Stafford, Huong-Thu Ton-Nu
  • HSP90 INHIBITORS
    Publication number: 20110053873
    Abstract: The invention relates to HSP90 inhibiting compounds consisting of the formula: (I) wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: January 30, 2009
    Publication date: March 3, 2011
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Young K. Chen, Eric Wang Co, Prasuna Guntupalli, John David Lawson, Wolfgang Reinhard Ludwig Notz, Jeffrey A. Stafford, Huong-Thu Ton-Nu
  • HSP90 INHIBITORS
    Publication number: 20090305998
    Abstract: The invention relates to HSP90 inhibiting compounds consisting of the formula: wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: January 30, 2009
    Publication date: December 10, 2009
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Young K. Chen, Erick Co, Prasuna Guntupalli, John D. Lawson, Wolfgang Reinhard Ludwig Notz, Jeffrey A. Stafford, Huong-Thu Ton-Nu
  • Convergent processes for the synthesis of a GARFT inhibitor containing a methyl substituted thiophene core and intermediates therefor
    Publication number: 20040266796
    Abstract: The invention relates to processes for the preparation of a GARFT inhibitor containing a methyl substituted thiophene core having the following structure: 1
    Type: Application
    Filed: June 23, 2004
    Publication date: December 30, 2004
    Applicant: AGOURON PHARMACEUTICALS, INC.
    Inventors: Elena Dovalsantos, Erik Jon Flahive, Brian John Halden, Mark Bryan Mitchell, Wolfgang Reinhard Ludwig Notz, Stacy Ann O'Neill-Slawecki, Qingping Tian
  • Convergent asymmetric route to produce a key intermediate towards the synthesis of a garft inhibitor
    Publication number: 20040266827
    Abstract: The invention relates to processes for the preparation of a key intermediate in the synthesis of a GARFT inhibitor of formula (Ia) containing a 4-methyl-substituted thiophene core: 1
    Type: Application
    Filed: June 16, 2004
    Publication date: December 30, 2004
    Applicant: AGOURON PHARMACEUTICALS, INC.
    Inventors: Wolfgang Reinhard Ludwig Notz, Carlos Alberto Martinez