Patents by Inventor Wolfgang Springer

Wolfgang Springer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Automatable rapid test for detection of cancer, based on telomerase (hTC) mRNA with specific primers and probes
    Patent number: 6808883
    Abstract: The invention relates to an automatable rapid test for detection of cancer based on telomerase(hTC) mRNA, to suitable starter nucleotides and oligonucleotide probes for this test and to a corresponding detection method and a test kit.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: October 26, 2004
    Assignee: Bayer AG
    Inventors: Wolfgang Springer, Gustav Hagen, Maresa Wick, Dmitry Zubov
  • Rapid DNA test for detecting quinolone-resistant Staphylococcus aureus pathogens in clinical material
    Patent number: 6015666
    Abstract: The invention describes starter oligonucleotide (primers), DNA probes and test methods for rapidly detecting quinolone-resistant Staphylococcus aureus pathogens in clinical sample material.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 18, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Springer, Klaus-Dieter Bremm, Rainer Endermann
  • Photochemical labelling of nucleic acids with digoxigenin reagents and their use in gene probe test systems
    Patent number: 5929108
    Abstract: The present invention concerns photochemical labelling reagents comprising a digoxigenin derivative and a furocoumarin derivative bound via a spacer. The labelling reagent can be used in gene diagnostic.
    Type: Grant
    Filed: March 31, 1997
    Date of Patent: July 27, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Antonius Lobberding, Gamal K. Mikhail, Wolfgang Springer
  • Nucleic acid-binding oligomers possessing C-branching for therapy and diagnostics
    Patent number: 5849893
    Abstract: The invention relates to nucleic acid-binding oligomers possessing C-branching of the general formula (I) ##STR1## and to the corresponding monomers, whose radicals have the meaning given in the description, and to their use as medicaments or diagnostic aids.
    Type: Grant
    Filed: September 24, 1996
    Date of Patent: December 15, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Antonius Lobberding, Burkhard Mielke, Christoph Schwemler, Eckhard Schwenner, Udo Stropp, Wolfgang Springer, Axel Kretschmer, Thorsten Potter
  • Pseudorabies virus (PRV) polynucleotides and their use for preparing virus-resistant eukaryotic cells
    Patent number: 5798265
    Abstract: The invention relates to polynucleotides which contain pseudorabies virus sequences, in particular sequences from the gII region of PRV, in the antisense orientation, their preparation and their use.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: August 25, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Springer, Jorg Baumgarten, Axel Kretschmer, Heinz Kolbl, Antonius Lobberding, Walter Strube, Peter Thein
  • Nucleic acid-binding oligomers possessing N-branching for therapy and diagnostics
    Patent number: 5623049
    Abstract: The invention relates to nucleic acid-binding oligomers possessing N-branching of the general formula (I), ##STR1## and their monomers, where the individual radicals have the meaning given in the description, and to their use as medicaments or as aids in diagnostics.
    Type: Grant
    Filed: September 6, 1994
    Date of Patent: April 22, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Antonius L obberding, Burkhard Mielke, Christoph Schwemler, Eckhard Schwenner, Udo Stropp, Wolfgang Springer, Axel Kretschmer, Thorsten P otter
  • Photochemical labelling of nucleic acids with digoxigenin reagents and their use in gene probe test systems
    Patent number: 5616731
    Abstract: The present invention concerns photochemical labelling reagents comprising a digoxigenin derivative and a furocoumarin derivative bound via a spacer. The labelling reagent can be used in gene diagnostic.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 1, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Antonius L obberding, Gamal K. Mikhail, Wolfgang Springer
  • HIV antisense expression vectors
    Patent number: 5583035
    Abstract: The present invention relates to the targeted blocking of the genetic information of the viral messenger ribonucleic acid (mRNA) for virus replication (e.g. of HIV) in transfected, haematopoietic cells with particularly suitable expression systems, which express a complementary "antisense RNA".
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: December 10, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Axel Kretschmer, Horst-Peter Antonicek, Jorg Baumgarten, Antonius Loebberding, Burkhard Mielke, Wolfgang Springer, Udo Stropp, Mark-Michael Struck, Lothar Biesert, Helga Rubsamen-Waigmann, Hary Suhartono, Thomas-Peter Hausner
  • Sulphocoumarin-containing nucleotides and their use in processes for detecting nucleic acids
    Patent number: 5547860
    Abstract: The invention relates to the preparation, as substituents, of nucleotides possessing a fluorescent coumarin residue, the enzymic incorporation of these nucleotides into nucleic acids and the detection of nucleic acids of defined sequence by hybridization with a complementary, coumarin-labelled nucleic acid.
    Type: Grant
    Filed: January 21, 1994
    Date of Patent: August 20, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jurgen Kocher, Wolfgang Springer, Eberhard Kuckert, Thomas Bocker
  • Specific gene probes and processes for the diagnostic investigation of Candida albicans
    Patent number: 5489513
    Abstract: Polynucleotide and oligonucleotide probes are described for the diagnostic investigation of mycoses which are caused by Candida albicans. These gene probes are complementary to parts of the genome of C. albicans and are suitable for identifying C. albicans nucleic acids in any sample material, even that which has been amplified. They do not hybridise with nucleic acids from other fungi, bacteria, animals or plants. Processes are described for the diagnosis of C. albicans in clinical samples as well.
    Type: Grant
    Filed: October 28, 1993
    Date of Patent: February 6, 1996
    Assignee: Bayer Akteingesellschaft
    Inventors: Wolfgang Springer, Manfred Plempel, Antonius Lobberding
  • Method for the detection and quantitative determination of nitrosomonas strains in wastewaters or soils
    Patent number: 5462855
    Abstract: For the detection and quantitative determination of nitrosomonas strains in wastewaters and soils, a gene probe is used which, by virtue of its complementary sequences, only hybridizes with parts of the genome of nitrosomonas strains from wastewater or soil samples and does not produce a positive hybridization signal with parts of the genome of other bacteria and the hybridized nucleic acid is quantitatively determined by means of a known label of the gene probe and thus provides a direct measure of the content of nitrosomonas strains in the wastewater or soil sample.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: October 31, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Springer, Hans G. Rast, Antonius Lobberding, Reinhard Kanne
  • Biologically active polymers
    Patent number: 5453461
    Abstract: The present invention relates to novel, biologically active polymers, methods for their preparation and their use for biochemical identification reactions and/or for further reaction with biologically active molecules such as, for example, proteins or nucleic acids.
    Type: Grant
    Filed: October 4, 1993
    Date of Patent: September 26, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ludger Heiliger, Eberhard Kuckert, Antonious Lobberding, Wolfgang Springer