Patents by Inventor Wolfgang Thielemann

Wolfgang Thielemann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxazolidinones for the Treatment of Inflammatory Conditions of the Gastrointestinal Tract
    Publication number: 20110172222
    Abstract: The present invention relates to the use of selective inhibitors of coagulation factor Xa, in particular of oxazolidinones of the formula (I), for the treatment and/or prophylaxis of inflammatory conditions of the gastrointestinal tract such as inflammatory bowel disease (IBD) and celiac disease and/or disorders related to inflammatory bowel disease (IBD) and/or celiac disease such as thromboembolic events (including e.g. pulmonary embolism (PE), arterial and venous thrombosis, myocardial infarction, stroke) as well their use for the preparation of pharmaceutical drugs for the treatment and/or prophylaxis of inflammatory bowel disease (IBD) and/or celiac disease and/or disorders related to inflammatory bowel disease (IBD) and/or celiac disease such as thromboembolic events.
    Type: Application
    Filed: June 23, 2009
    Publication date: July 14, 2011
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Georges Von Degenfeld, Elisabeth Perzborn, Wolfgang Thielemann, Susanne Röhrig, Fiona McDonald
  • Oxazolidinones For the Treatment and/or Prophylaxis of Heart Failure
    Publication number: 20110003804
    Abstract: The present invention relates to the use of selective inhibitors of coagulation factor Xa, in particular of oxazolidinones of the formula (I), for the treatment and/or prophylaxis of heart failure and/or disorders related to heart failure as well as their use for the preparation of pharmaceutical drugs for the treatment and/or prophylaxis of heart failure and/or disorders related to heart failure.
    Type: Application
    Filed: December 3, 2008
    Publication date: January 6, 2011
    Inventors: Harald Kallabis, Wolfgang Thielemann, Elisabeth Perzborn, Susanne Röhrig, Dagmar Kubitza, Theodore Spiro, Lloyd Haskell, Jeet Mahal
  • Use of Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines in the treatment of nausea and vomiting
    Patent number: 7709504
    Abstract: The present invention relates to the use of substituted 2-thio-3,5-dicyano-4-phenyl-6-amino-pyridines of the formula (I) wherein the terms A and R2 are herein defined, for treatment of nausea and vomiting.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: May 4, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Thomas Krahn, Wolfgang Thielemann, Ulrich Rosentreter, Nicole Diedrichs, Thomas Krämer
  • novel use of activators and stimulators of soluble guanylate cyclase for the prevention or treatment of renal disorders
    Publication number: 20100016305
    Abstract: The present invention relates generally to a method for the treatment of renal failure or renal hypertension and, more particularly, for improving the recovery from acute renal failure or renal hypertension by treatment with activators of soluble guanylate cyclase or stimulators of guanylate cyclase.
    Type: Application
    Filed: July 6, 2006
    Publication date: January 21, 2010
    Applicant: Bayer Healthcare AG
    Inventors: Thomas Krahn, Johannes-Peter Stasch, Gerrit Weimann, Wolfgang Thielemann, Matthias Rinke
  • Use of Activators of Soluble Guanylate Cyclase for Treating Reperfusion Damage
    Publication number: 20090298822
    Abstract: The present invention relates to the use of compounds for manufacturing a pharmaceutical product/medicament for the prophylaxis and/or treatment of reperfusion damage.
    Type: Application
    Filed: July 6, 2006
    Publication date: December 3, 2009
    Applicant: Bayer Health Care
    Inventors: Thomas Krahn, Johannes-peter Stasch, Gerrit Weimann, Wolfgang Thielemann
  • Use of Suluble Guanylate Cyclase Acitvators for Treating Acute and Chronic Lung Diseases
    Publication number: 20090286781
    Abstract: The present invention relates to the use of compounds of the formulae I-VI for manufacturing a pharmaceutical for the treatment of acute and chronic lung disorders such as the respiratory distress syndromes [acute lung injury (ALI), acute respiratory distress syndrome (ARDS)] and the treatment of COPD.
    Type: Application
    Filed: September 23, 2006
    Publication date: November 19, 2009
    Applicant: Bayer HealtHCare AG
    Inventors: Thomas Krahn, Johannes-peter Stasch, Gerrit Weimann, Wolfgang Thielemann
  • Use of Activators of Soluble Guanylate Cyclase for Promoting Wound Healing
    Publication number: 20090221573
    Abstract: The present invention relates to a method for promoting wound healing by administering one or more compounds identified in the claims, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: July 6, 2006
    Publication date: September 3, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Thomas Krahn, Johannes-Peter Stasch, Gerrit Weimann, Wolfgang Thielemann, Beatrix Stelte-Ludwig
  • Use of soluble guanylate cyclase activators for the treatment of Raynaud's Phenomenon
    Publication number: 20090215769
    Abstract: The present invention relates to a method for prevention or treatment of primary and secondary Raynaud's phenomenon comprising administration of an effective amount of a compound selected from compounds of formulae I-IV, and to pharmaceutical compositions containing these compounds.
    Type: Application
    Filed: July 4, 2006
    Publication date: August 27, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Thomas Krahn, Johannes-Peter Stasch, Gerrit Weimann, Wolfgang Thielemann
  • Use of Substituted 2-Thio-3,5-Dicyano-4-Phenyl-6-Aminopyridines In the Treatment of Nausea and Vomiting
    Publication number: 20080249133
    Abstract: The present invention relates to the use of substituted 2-thio-3,5-dicyano-4-phenyl-6-amino-pyridines of the formula (I) for production of a medicament for the prophylaxis and/or treatment of nausea and vomiting.
    Type: Application
    Filed: June 23, 2005
    Publication date: October 9, 2008
    Applicant: Bayer Healthcare AG
    Inventors: Thomas Krahn, Wolfgang Thielemann, Ulrich Rosentreter, Nicole Diedrichs, Thomas Kramer
  • Substituted phenylcyclohexanecarboxamides and their use
    Patent number: 7074780
    Abstract: The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in medicaments, in particular for the prevention and/or treatment of cardiovascular disorders.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: July 11, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erwin Bischoff, Thomas Krahn, Stephan-Nicholas Müller, Holger Paulsen, Joachim Schuhmacher, Henning Steinhagen, Wolfgang Thielemann
  • Indolin phenylsulfonamide derivatives
    Publication number: 20060100230
    Abstract: The invention relates to novel substituted indolin phenylsulfonamide derivatives, to a method for the production thereof and to the use thereof in medicaments, especially as potent PPAR-delta activating compounds for the prophylaxis and/or treatment of cardiovascular diseases, especially dyslipidaemia and coronary heart diseases.
    Type: Application
    Filed: June 30, 2003
    Publication date: May 11, 2006
    Inventors: Hilmar Bischoff, Elke Dittrich-Wengenroth, Martina Wuttke, Heike Heckroth, Wolfgang Thielemann, Michael Woltering, Michael Otteneder
  • Substituted phenylcyclohexane carboxylic acid amides and their use as adenosine uptake inhibitors
    Patent number: 6984642
    Abstract: The present invention relates to substituted phenylcyclohexanecaboxamides of the formula (I), to processes for their preparation and to their use in medicaments, in particular for treating cardiovascular disorders.
    Type: Grant
    Filed: May 16, 2000
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erwin Bischoff, Stephan Lensky, Stephan-Nicholas Müller, Holger Paulsen, Jörg Keldenich, Thomas Krahn, Joachim Schuhmacher, Jan Jänichen, Wolfgang Thielemann, Henning Steinhagen
  • Substituted piperazine cyclohexane carboxilic acid amides and the use thereof
    Publication number: 20050054637
    Abstract: The present invention relates to substituted piperazinecyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in pharmaceuticals, in particular for the prophylaxis and/or treatment of cardiovascular disorders.
    Type: Application
    Filed: October 1, 2002
    Publication date: March 10, 2005
    Inventors: Erwin Bischoff, Thomas Krahn, Holger Paulsen, Joachim Schuhmacher, Henning Steinhagen, Wolfgang Thielemann
  • Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases
    Publication number: 20040235830
    Abstract: The invention relates to substituted cyclohexane derivates of formula (I), a method for the production thereof and the use thereof in medicaments, particularly for preventing and/or treating cardiovascular diseases, diseases of the urogenital tract and cerebrovascular diseases.
    Type: Application
    Filed: April 22, 2004
    Publication date: November 25, 2004
    Inventors: Susanne Rohrig, Andreas Stolle, Julio C. Castro-Palomino, Helmut Haning, Gabriele Handke-Erguden, Noemi Daviu-Folguera, Holger Paulsen, Josef Pernerstorfer, Stephan-Nicholas Wirtz, Henning Steinhagen, Wolfgang Thielemann, Erwin Bischoff, Ulrich Ebbinghaus-Kintscher, Peter Ellinghaus, Joachim Hutter, Thomas Krahn, Frank Wunder, Klemens Lustig, Joachim Schuhmacher, Frank Sussmeier
  • Substituted phenylcyclohexanecarboxamides and their use
    Publication number: 20040122004
    Abstract: The present invention relates to substituted phenylcyclohexanecarboxamides of the Formula (I) 1
    Type: Application
    Filed: November 17, 2003
    Publication date: June 24, 2004
    Applicant: Bayer Aktiengesellschaft
    Inventors: Erwin Bischoff, Thomas Krahn, Stephan-Nicholas Muller, Holger Paulsen, Joachim Schuhmacher, Henning Steinhagen, Wolfgang Thielemann
  • Substituted phenylcyclohexanecarboxamides and their use
    Patent number: 6649616
    Abstract: The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in medicaments, in particular for the prevention and/or treatment of cardiovascular disorders.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: November 18, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erwin Bischoff, Thomas Krahn, Stephan-Nicholas Müller, Holger Paulsen, Joachim Schuhmacher, Henning Steinhagen, Wolfgang Thielemann
  • Substituted phenylcyclohexanecarboxamides and their use
    Publication number: 20030008881
    Abstract: The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) 1
    Type: Application
    Filed: August 30, 2001
    Publication date: January 9, 2003
    Inventors: Erwin Bischoff, Thomas Krahn, Stephan-Nicholas Muller, Holger Paulsen, Joachim Schuhmacher, Henning Steinhagen, Wolfgang Thielemann