Patents by Inventor Won Jai LEE

Won Jai LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition for preventing or treating keloid or hypertrophic scars
    Patent number: 10864283
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating a keloid disease or scars. The inventors of the present invention discovered that mortalin expression inhibition and the interaction between mortalin and p53 may be new targets for keloid treatment. In the present invention, apoptosis and an anti-fibrotic effect were verified by preparing a mortalin-specific shRNA (dE1-RGD/GFP/shMOT) and injecting same in a keloid spheroid. Thus, by reducing ECM expression and inducing apoptosis in a keloid spheroid, mortalin knockdown may be very usefully employed for keloid treatment.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: December 15, 2020
    Inventors: Chae Ok Yun, Won Jai Lee
  • COMPOSITION FOR PREVENTING OR TREATING KELOID OR HYPERTROPHIC SCARS
    Publication number: 20180326094
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating a keloid disease or scars. The inventors of the present invention discovered that mortalin expression inhibition and the interaction between mortalin and p53 may be new targets for keloid treatment. In the present invention, apoptosis and an anti-fibrotic effect were verified by preparing a mortalin-specific shRNA (dE1-RGD/GFP/shMOT) and injecting same in a keloid spheroid. Thus, by reducing ECM expression and inducing apoptosis in a keloid spheroid, mortalin knockdown may be very usefully employed for keloid treatment.
    Type: Application
    Filed: July 5, 2018
    Publication date: November 15, 2018
    Inventors: Chae Ok YUN, Won Jai LEE