Patents by Inventor Won Jin Ho

Won Jin Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATIONS OF 15-PGDH INHIBITORS WITH CORTICOSTEROIDS AND/OR TNF INHIBITORS AND USES THEREOF
    Publication number: 20230355636
    Abstract: A method of treating intestinal, gastrointestinal, or bowel disorders in a subject in need thereof includes administering to the subject a therapeutically effective amount of 15-PGDH inhibitor alone or in combination with a corticosteroid and/or TNF alpha antagonist.
    Type: Application
    Filed: May 5, 2023
    Publication date: November 9, 2023
    Inventors: Sanford Markowitz, Won Jin Ho, Stephen P. Fink, Vinay Varadan
  • Combinations of 15-PGDH inhibitors with corticosteroids and/or TNF inhibitors and uses thereof
    Patent number: 11690847
    Abstract: A method of treating intestinal gastrointestinal, or bowel disorders in a subject in need thereof includes administering to the subject a therapeutically effective amount of 15-PGDH inhibitor alone or in combination with a corticosteroid and/or TNF alpha antagonist.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: July 4, 2023
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Sanford Markowitz, Won Jin Ho, Stephen P. Fink, Vinay Varadan
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING CORONARY DISORDERS
    Publication number: 20230165883
    Abstract: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Application
    Filed: August 23, 2022
    Publication date: June 1, 2023
    Inventors: Sanford Markowitz, Won Jin Ho, Yiyuan Yuan, Mukesh Jain, Mohamad Sabeh, Joseph Ready, Noelle Williams
  • Inhibitors of short-chain dehydrogenase activity for treating coronary disorders
    Patent number: 11426420
    Abstract: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Grant
    Filed: April 9, 2018
    Date of Patent: August 30, 2022
    Assignees: CASE WESTERN RESERVE UNIVERSITY, BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Sanford Markowitz, Won Jin Ho, Yiyuan Yuan, Mukesh Jain, Mohamed Sabeh, Joseph Ready, Noelle Williams
  • TARGETING PTPN22 IN CANCER THERAPY
    Publication number: 20220267274
    Abstract: Described are methods of treating solid cancers in a subject. The methods comprise the steps of administering to the subject having the solid cancer or prone of getting the solid cancer an antagonist of PTPN22, or the functional part of PTPN22, and treating the solid cancer. Methods comprising use of other anticancer agents and adjuvants in conjunction with PTPN22 inhibitors are also provided.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 25, 2022
    Inventors: Elizabeth Jaffee, Won Jin Ho
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING FIBROSIS
    Publication number: 20210283113
    Abstract: A method of treating or preventing a fibrotic disease, disorder or condition includes administering to a subject in need of treatment a 15-PGDH inhibitor.
    Type: Application
    Filed: December 23, 2020
    Publication date: September 16, 2021
    Inventors: Sanford Markowitz, Stanton Gerson, Amar Desai, Won Jin Ho
  • Inhibitors of short-chain dehydrogenase activity for treating fibrosis
    Patent number: 10945998
    Abstract: A method of treating or preventing a fibrotic disease, disorder or condition includes administering to a subject in need of treatment a 15-PGDH inhibitor.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: March 16, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Sanford Markowitz, Stanton Gerson, Amar Desai, Won Jin Ho
  • COMBINATIONS OF 15-PGDH INHIBITORS WITH CORCOSTEROIDS AND/OR TNF INHIBITORS AND USES THEREOF
    Publication number: 20200061073
    Abstract: A method of treating intestinal gastrointestinal, or bowel disorders in a subject in need thereof includes administering to the subject a therapeutically effective amount of 15-PGDH inhibitor alone or in combination with a corticosteroid and/or TNF alpha antagonist.
    Type: Application
    Filed: November 30, 2017
    Publication date: February 27, 2020
    Inventors: Sanford Markowitz, Won Jin Ho, Stephen P. Fink, Vinay Varadan
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING CORONARY DISORDERS
    Publication number: 20200030348
    Abstract: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Application
    Filed: April 9, 2018
    Publication date: January 30, 2020
    Inventors: Sanford Markowitz, Won Jin Ho, Yiyuan Yuan, Mukesh Jain, Mohamed Sabeh, Joseph Ready, Noelle Williams
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING FIBROSIS
    Publication number: 20180064694
    Abstract: A method of treating or preventing a fibrotic disease, disorder or condition includes administering to a subject in need of treatment a 15-PGDH inhibitor.
    Type: Application
    Filed: March 8, 2016
    Publication date: March 8, 2018
    Inventors: Sanford Markowitz, Stanton Gerson, Amar Desai, Won Jin Ho