Abstract: A composite wire material may comprise a core wire comprising copper (Cu). The core wire material may comprise a first layer on a circumferential surface of the core wire, where the first layer comprises graphene. The composite wire material may comprise a second layer on a circumferential surface of the first layer, where the second layer comprises nickel (Ni).

Abstract: A system and method for studying cell injury mechanisms by applying biologically relevant mechanical impact to in vitro cell culture are disclosed. This approach is for maintaining consistent in vitro conditions during experiments, accommodating multiple cell populations, and monitoring each in real-time while achieving amplitude and time scale of input acceleration that mimic blunt injury cases. These multiplexed, environmental control capabilities enable characterizing the relationships between mechanical impact and cell injury in multivariate biological systems.

Abstract: A system for mechanical testing a specimen includes a 3D printed mechanical testing fixture; a linear actuator having an axis of movement; a controller configured to control the linear actuator; two cameras; a data-acquisition system configured to acquire data from the linear actuator, the controller, and the two cameras; and the specimen. The specimen is marked in two locations with tracking markers to provide indication to the data acquisition system via at least one camera of movement and change in length of the specimen. The fixture includes force-sensing beams extending perpendicular to the axis of force.

Abstract: A system for mechanical testing a specimen includes a 3D printed mechanical testing fixture; a linear actuator having an axis of movement; a controller configured to control the linear actuator; two cameras; a data-acquisition system configured to acquire data from the linear actuator, the controller, and the two cameras; and the specimen. The specimen is marked in two locations with tracking markers to provide indication to the data acquisition system via at least one camera of movement and change in length of the specimen.

Abstract: A system and method for studying cell injury mechanisms by applying biologically relevant mechanical impact to in vitro cell culture are disclosed. This approach is for maintaining consistent in vitro conditions during experiments, accommodating multiple cell populations, and monitoring each in real-time while achieving amplitude and time scale of input acceleration that mimic blunt injury cases. These multiplexed, environmental control capabilities enable characterizing the relationships between mechanical impact and cell injury in multivariate biological systems.

Abstract: According to example embodiments of the invention, a microscale testing stage comprises a frame having first and second opposing ends and first and second side beams, at least one deformable force sensor beam, a first longitudinal beam having a free end, a second longitudinal beam having a facing free end, a support structure, and a pair of slots disposed at each of the free ends. In certain embodiments, a layer of a conductive material defines first and second conductive paths and an open circuit that can be closed by the specimen across the gap. In other embodiments, the stage is formed of a high melting temperature material.

Abstract: According to example embodiments of the invention, a microscale testing stage comprises a frame having first and second opposing ends and first and second side beams, at least one deformable force sensor beam, a first longitudinal beam having a free end, a second longitudinal beam having a facing free end, a support structure, and a pair of slots disposed at each of the free ends. In certain embodiments, a separately fabricated microscale or nanoscale specimen comprises a central gauge length portion of a material to be tested, and first and second hinges providing a self-aligning mechanism for uniaxial loading. In other embodiments, a layer of a conductive material defines first and second conductive paths and an open circuit that can be closed by the specimen across the gap. In other embodiments, the stage is formed of a high melting temperature material.

Abstract: According to example embodiments of the invention, a microscale testing stage comprises a frame having first and second opposing ends and first and second side beams, at least one deformable force sensor beam, a first longitudinal beam having a free end, a second longitudinal beam having a facing free end, a support structure, and a pair of slots disposed at each of the free ends. In certain embodiments, a separately fabricated microscale or nanoscale specimen comprises a central gauge length portion of a material to be tested, and first and second hinges providing a self-aligning mechanism for uniaxial loading. In other embodiments, a layer of a conductive material defines first and second conductive paths and an open circuit that can be closed by the specimen across the gap. In other embodiments, the stage is formed of a high melting temperature material.