Patents by Inventor Xavier Serra Masia

Xavier Serra Masia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sodium salt of 5-cyclopropyl-2-{[2-(2,6-difluorophenyl)pyrimidin-5-yl]amino}benzoic acid as DHODH inhibitor
    Patent number: 8501943
    Abstract: The present disclosure is directed to the sodium salt of 5-cyclopropyl-2-{[2-(2,6-difluorophenyl)pyrimidin-5-yl]amino}benzoic acid, pharmaceutically acceptable solvates thereof, pharmaceutical combinations thereof, and methods of treatment.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: August 6, 2013
    Assignee: Almirall, S.A.
    Inventors: Nuria Garcia Gonzalez, Francesc Carrera Carrera, Monserrat Julia Jane, Laurent Debethune, Xavier Serra Masia
  • ADDITION SALTS OF TROMETHAMINE WITH AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS
    Publication number: 20120003183
    Abstract: The present disclosure is directed to novel crystalline addition salts of (i) tromethamine with (ii) an azabiphenylaminobenzoic acid derivatives of formula (I), pharmaceutically acceptable solvates thereof, pharmaceutical combinations thereof, and methods of treatment.
    Type: Application
    Filed: March 11, 2010
    Publication date: January 5, 2012
    Inventors: Nuria Garcia Gonzalez, Francesc Carrera Carrera, Monserrat Julia Jane, Laurent Debethune, Xavier Serra Masia
  • SODIUM SALT OF 5-CYCLOPROPYL-2-BENZOIC ACID AS DHODH INHIBITOR
    Publication number: 20120003184
    Abstract: The present disclosure is directed to the sodium salt of 5-cyclopropyl-2-{[2-(2,6-difluorophenyl)pyrimidin-5-yl]amino}benzoic acid, pharmaceutically acceptable solvates thereof, pharmaceutical combinations thereof, and methods of treatment.
    Type: Application
    Filed: March 11, 2010
    Publication date: January 5, 2012
    Inventors: Nuria Garcia Gonzalez, Francesc Carrera Carrera, Monserrat Julia Jane, Laurent Debethune, Xavier Serra Masia
  • PROCESS FOR PREPARING 3-METHYL-4-PHENYLISOXAZOLO [3,4-D]PYRIDAZIN-7(6H)-ONE
    Publication number: 20100137591
    Abstract: A process for preparing 3-methyl-4-phenylisoxazolo[3,4-d]pyridazin-7(6H)-one which process comprises the steps of: (a) reacting 1-phenylbutane-1,3-dione with ethyl 2-chloro-2-(hydroxyimino)actetate; and (b) subsequently reacting the product from step (a) with hydrazine or an hydrate thereof to yield 3-methyl-4-phenylisoxazolo-[3,4-d]pyridin-7(6H)-one, wherein step (b) is carried out on the mixture resulting from step (a) without isolating ethyl 4-benzoyl-5-methylisoxazole-3-carboxylate therefrom.
    Type: Application
    Filed: February 13, 2008
    Publication date: June 3, 2010
    Inventors: Iolanda Marchueta Hereu, Xavier Serra Masia
  • Nitric esters from derivatives of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid and their preparation process
    Patent number: 5844696
    Abstract: Nitric esters from derivatives of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid with the formula (I), where: ?A.ident.F, Cl or Br; X.ident.O, NH or NR (R.ident.C.sub.1 -C.sub.8 alkyl); R.sub.1 and R.sub.2 independently.ident.C.sub.1 -C.sub.8 alkyl and n is a whole number from 1 to 10. The procedure includes the condensation of 2-(2,6-diahlophenylamino) phenylacetoxyacetic acid with a compound with the formula: ##STR1## where Y.ident.OH, NH.sub.2 or NHR and Z is Cl, Br or ONO.sub.2.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: December 1, 1998
    Assignee: Prodes, S.A.
    Inventors: Xavier Serra Masia, Joan Pi Sallent