Patents by Inventor Xi Yu
Xi Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148098Abstract: A helmet is provided that can include a cage defining a front end, a back end opposite the front end, a first lateral end and a second lateral end opposite the first lateral end. The cage can include multiple longitudinal beams that extend between the back end of the cage and the front end of the cage; and a transverse beam that extends between the first lateral end of the cage and the second lateral end of the cage. The transverse beam can be anchored to the multiple longitudinal beams. The helmet can include a body that fully encapsulates the multiple longitudinal beams of the cage and that partially encapsulates the transverse beam. The body can define multiple vents. Each vent can be situated between two adjacent longitudinal beams. The transverse beam can extend through one of the multiple vents.Type: ApplicationFiled: March 4, 2022Publication date: May 9, 2024Inventors: Ming Xi Yu, Allen Albert Bischofberger, Christopher Thomas Pietrzak, Michael Joseph Krynock
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Patent number: 11977297Abstract: A splicing type light board and a display device are provided with a first LED light board and a second LED light board; a first end of the first LED light board near a first signal input terminal, and a second end away from the first signal input terminal; a first end of the second LED light board near a second signal input terminal, and a second end away from the second signal input terminal; and the first end of the first LED light board connecting the first end of the second LED light board or the second end of the first LED light board connecting the second end of the second LED light board.Type: GrantFiled: April 2, 2021Date of Patent: May 7, 2024Inventors: Xi Cheng, Gang Yu
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Publication number: 20240141347Abstract: An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.Type: ApplicationFiled: September 28, 2023Publication date: May 2, 2024Inventors: Chenyu ZHANG, Xi CHEN, Zheng FU, Jing LI, Xiang ZHANG, Xinyan ZHOU, Li ZHANG, Mengchao YU, Hongyuan GUO
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Publication number: 20240141361Abstract: Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.Type: ApplicationFiled: September 28, 2023Publication date: May 2, 2024Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
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Publication number: 20240141344Abstract: Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.Type: ApplicationFiled: September 28, 2023Publication date: May 2, 2024Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
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Publication number: 20240141380Abstract: Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.Type: ApplicationFiled: September 28, 2023Publication date: May 2, 2024Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
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Publication number: 20240118150Abstract: The present disclosure provides a method for testing an internal force increment of an arch bridge suspender by inertial measurement, including the following steps: (1) selecting a suspender to be tested with internal force increment, and mounting an acceleration sensing device or a speed sensing device at a lower edge of the suspender to be tested; (2) setting an appropriate sampling frequency and collecting signals; (3) processing information data collected in step (2) by using Formulas; and (4) recording a result of the information data processing and obtaining the internal force increment of the suspender. The method can obtain the internal force increment of the suspender by collecting acceleration or speed signals of the lower edge of the suspender and performing calculation from the signals. This method has the advantages of simple and convenient testing, high replicability and low test cost.Type: ApplicationFiled: October 8, 2021Publication date: April 11, 2024Inventors: Hua Wang, Longlin Wang, Tianzhi Hao, Zehua Xie, Mengsheng Yu, Xiaoli Zhuo, Yuhou Yang, Jiejun Ning, Xirui Wang, Xi Peng, Kainan Huang, Junhong Wu
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Patent number: 11945805Abstract: Compounds are provided as inhibitors of CXCR2, having the structure:Type: GrantFiled: April 29, 2021Date of Patent: April 2, 2024Assignee: CHEMOCENTRYX, INCInventors: Xi Chen, Dean R. Dragoli, Junfa Fan, Jaroslaw Kalisiak, Manmohan Reddy Leleti, Viengkham Malathong, Jeffrey McMahon, Hiroko Tanaka, Ju Yang, Chao Yu, Penglie Zhang, Venkat Mali
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Patent number: 11923948Abstract: Embodiments of the present invention provide a communication method and a communications apparatus. The method includes: receiving configuration information of at least one frequency resource group, and receiving, by using at least one beam, a downlink signal on a corresponding frequency resource in the at least one frequency resource group, wherein each frequency resource group comprises at least two frequency resources, each frequency resource corresponds to at least one beam, and the configuration information comprises an identifier of each frequency resource group and an identifier of each frequency resource; and when it is detected based on the downlink signal that a beam associated with a first frequency resource in the frequency resource group fails, sending a beam recovery request on a second frequency resource in the frequency resource group. Correspondingly, a corresponding apparatus is further disclosed.Type: GrantFiled: April 8, 2022Date of Patent: March 5, 2024Assignee: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Peng Guan, Xi Zhang, Ying Sun, Ziming Yu
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Publication number: 20230297823Abstract: Embodiments of the present disclosure disclose a method and a system for training a neural network for improving adversarial robustness. The method includes collecting a plurality of data samples comprising clean data samples and adversarial data samples. The training of the neural network includes training of a probabilistic encoder to encode the plurality of data samples into a probabilistic distribution over a latent space representation. In addition, the training of the neural network comprising training of a classifier to classify an instance of the latent space representation to produce a classification result. In addition, the method includes training shared parameters of a first instance of the neural network using the clean data samples and a second instance of the neural network using the adversarial data samples. Further, the method includes outputting the shared parameters of the first instance of the neural network and the second instance of the neural network.Type: ApplicationFiled: March 18, 2022Publication date: September 21, 2023Inventors: Ye Wang, Xi Yu, Niklas Smedemark-Margulies, Shuchin Aeron, Toshiaki Koike-Akino, Pierre Moulin, Matthew Brand, Kieran Parsons
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Patent number: 11731224Abstract: Disclosed are systems for applying materials to components. The system comprises a tool operable for transferring a portion of a material from a supply of the material to a component. A first portion of the tool may be configured for cutting along a side or edge of the portion of the material. A second portion of the tool may be configured for tamping, pressing, or pushing against the portion of the material to cause uncut sides or edges of the portion of the material attached to the supply of the material to be torn, severed, detached, or separated from the supply of the material.Type: GrantFiled: October 8, 2021Date of Patent: August 22, 2023Assignee: Laird Technologies, Inc.Inventors: Tsang-I Tsai, Yi-Shen Lin, Min-Wei Hsu, Chen-Xi Yu
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Patent number: 11635453Abstract: A three-phase load is powered by a PWM (e.g., SVPWM) driven DC-AC inverter having a single shunt-topology. A shunt voltage and a branch voltage of the inverter (across a transistor to be calibrated) are measured during a second period of each SVPWM sector, and the drain-to-source resistance of the calibrated transistor is calculated. During the fourth period of each SVPWM sector, the branch voltage is measured again, and another branch voltage across another transistor is measured. Using the drain-to-source resistance of the calibrated transistor and the voltage across the calibrated transistor measured during the fourth period, the phase current through the calibrated transistor is calculated. Using the other branch voltage measured during the fourth period and the drain-to-source resistance of its corresponding transistor (known from a prior SVPWM sector), the phase current through that transistor is calculated. From the two calculated phase currents, the other phase current can be calculated.Type: GrantFiled: July 16, 2021Date of Patent: April 25, 2023Assignees: STMicroelectronics S.r.l., STMicroelectronics (Shenzhen) R&D Co. LtdInventors: Dino Costanzo, Cheng Pan Cai, Xi Yu Xu
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Publication number: 20220401082Abstract: Aspects of the invention provide a biological sample collection pad (e.g., for the collection of fecal, liquid or tissue samples). Method of using such pads and analyzing collected samples are also provided.Type: ApplicationFiled: October 20, 2020Publication date: December 22, 2022Inventors: Stanislav FORMAN, Xi-Yu JIA, Ian FORSYTHE
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Publication number: 20220251627Abstract: Provided herein are aqueous compositions, kits and methods for the stabilization of cell-free nucleic acids. Provided herein are aqueous compositions for the stabilization of a cell-free nucleic acid (cfNA) population in a blood sample. In certain embodiments, the aqueous composition comprises a polyvinylpyrrolidone (PVP), an apoptosis inhibitor and one or more eryptosis inhibitors.Type: ApplicationFiled: June 26, 2020Publication date: August 11, 2022Applicant: ZYMO RESEARCH CORPORATIONInventors: Hanjun KIM, Ryan KEMP, Xi-Yu JIA
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Patent number: 11406989Abstract: Provided herein are devices and methods for sample isolation comprising a planar member configured to rotate around a bearing, and a plurality of apertures positioned at an angle to the planar member. Exemplary embodiments relate generally to the field of sample isolation, and more particularly to sample isolation using centrifugal and magnetic forces.Type: GrantFiled: April 25, 2019Date of Patent: August 9, 2022Assignee: ZYMO RESEARCH CORPORATIONInventors: Xi-Yu Jia, Samuel Joseph Ollar
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Publication number: 20220214384Abstract: A three-phase load is powered by a PWM (e.g., SVPWM) driven DC-AC inverter having a single shunt-topology. A shunt voltage and a branch voltage of the inverter (across a transistor to be calibrated) are measured during a second period of each SVPWM sector, and the drain-to-source resistance of the calibrated transistor is calculated. During the fourth period of each SVPWM sector, the branch voltage is measured again, and another branch voltage across another transistor is measured. Using the drain-to-source resistance of the calibrated transistor and the voltage across the calibrated transistor measured during the fourth period, the phase current through the calibrated transistor is calculated. Using the other branch voltage measured during the fourth period and the drain-to-source resistance of its corresponding transistor (known from a prior SVPWM sector), the phase current through that transistor is calculated. From the two calculated phase currents, the other phase current can be calculated.Type: ApplicationFiled: July 16, 2021Publication date: July 7, 2022Applicants: STMicroelectronics S.r.l., STMicroelectronics (Shenzhen) R&D Co. LtdInventors: Dino COSTANZO, Cheng Pan CAI, Xi Yu XU
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Publication number: 20220186207Abstract: Solutions, reagents, and methods for nucleic acid purification. In certain aspects, cationic surfactant and, optionally, an anionic surfactant solutions are provided which can be used for phase separation and capture of nucleic acids, such as plasmid or genomic DNA, to a solid phase carrier, such as a mineral matrix.Type: ApplicationFiled: December 17, 2021Publication date: June 16, 2022Inventors: Ryan KEMP, Jonathan A. CLAYPOOL, Marc E. VAN EDEN, Xi-Yu JIA
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Patent number: 11236325Abstract: Solutions, reagents, and methods for nucleic acid purification. In certain aspects, cationic surfactant and, optionally, an anionic surfactant solutions are provided which can be used for phase separation and capture of nucleic acids, such as plasmid or genomic DNA, to a solid phase carrier, such as a mineral matrix.Type: GrantFiled: April 25, 2018Date of Patent: February 1, 2022Assignee: ZYMO RESEARCH CORPORATIONInventors: Ryan Kemp, Jonathan A. Claypool, Marc E. Van Eden, Xi-Yu Jia
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Publication number: 20220023984Abstract: Disclosed are systems for applying materials to components. The system comprises a tool operable for transferring a portion of a material from a supply of the material to a component. A first portion of the tool may be configured for cutting along a side or edge of the portion of the material. A second portion of the tool may be configured for tamping, pressing, or pushing against the portion of the material to cause uncut sides or edges of the portion of the material attached to the supply of the material to be torn, severed, detached, or separated from the supply of the material.Type: ApplicationFiled: October 8, 2021Publication date: January 27, 2022Inventors: Tsang-I TSAI, Yi-Shen LIN, Min-Wei HSU, Chen-Xi YU
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Patent number: D965174Type: GrantFiled: July 17, 2020Date of Patent: September 27, 2022Assignee: ZYMO RESEARCH CORPORATIONInventors: Xi-Yu Jia, Marc E. Van Eden, Stanislav Forman