Abstract: An anti-cavitation damping composite metal structure for a flow passage component and a preparation method thereof are provided. The preparation method includes: cladding a gradient functional material layer by layer on a substrate of a flow passage component; forming periodic structures on a surface of each layer of the gradient functional material through etching by an ultrafast laser to absorb a part of an impact load energy caused by cavitation of the flow passage component, where the layers of the gradient functional material form a gradient coating with a toughness increasing layer by layer and a hardness decreasing layer by layer from bottom to top; and forming nano twins on a surface layer by a laser shock peening technique, and implanting a residual compressive stress to further improve anti-cavitation resistance of a surface.

Abstract: There are provided isotope-enriched compounds containing stable heavy isotope-enriched amide functional groups for modulating the pharmacokinetic profile, metabolic profile, and/or delivery efficiency of a drug or prodrug, as well as its therapeutic or prophylactic efficacy and/or adverse effects. Use of the isotope-enriched amide-containing drugs and prodrugs for the treatment or prevention of disease states and conditions is also provided.

Abstract: A transaction record is created showing a purchase transaction of a customer. A CV profile showing a list of items in the transaction obtained from images is also obtained. The items in the transaction record are compared to items on the list. When there is a discrepancy, an action to take is determined.

Abstract: A continuously variable transmission with both equal-difference output and equal-ratio output includes an input mechanism, a hydraulic transmission mechanism, a planetary-gear-set convergence mechanism, an equal-difference output mechanism, an equal-ratio output mechanism, a clutch assembly, and a brake. The clutch assembly connects an output end of the input mechanism to an input end of the hydraulic transmission mechanism and the planetary-gear-set convergence mechanism and connects an output end of the hydraulic transmission mechanism to the planetary-gear-set convergence mechanism. The clutch assembly connects the planetary-gear-set convergence mechanism to the equal-difference output mechanism and the equal-ratio output mechanism. The clutch assembly connects the equal-ratio output mechanism to the equal-difference output mechanism.

Abstract: A continuously variable transmission with both equal-difference output and equal-ratio output includes an input mechanism, a hydraulic transmission mechanism, a planetary-gear-set convergence mechanism, an equal-difference output mechanism, an equal-ratio output mechanism, a clutch assembly, and a brake. The clutch assembly connects an output end of the input mechanism to an input end of the hydraulic transmission mechanism and the planetary-gear-set convergence mechanism and connects an output end of the hydraulic transmission mechanism to the planetary-gear-set convergence mechanism. The clutch assembly connects the planetary-gear-set convergence mechanism to the equal-difference output mechanism and the equal-ratio output mechanism. The clutch assembly connects the equal-ratio output mechanism to the equal-difference output mechanism.

Abstract: The disclosure relates to KRASG12D inhibitor compounds having the structure of Formula (A) or Formula (B), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRASG12D mutation-associated diseases, disorders and conditions.

Abstract: Technology is disclosed herein for a memory system that compensates for different programming speeds in two sets of memory cells when reading those two sets of memory cells. The memory system programs a group of the memory cells to one or more data states. In one aspect, the memory cells are not verified during programming. The group has a first set of memory cells that program at a first speed and a second set of memory cells that program at a second speed. The memory system reads the first set of the memory cells with a first set of read parameters and reads the second set of the memory cells with a second set of read parameters. The first set of read parameters are different from the second set of read parameters to compensate for the different programming speeds.

Abstract: Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. The disclosure further relates to methods and compositions for use in the treatment of neoplastic disorders by administering the antibody-drug conjugates provided herein. In an embodiment, the splicing modulator comprises a pladienolide or a pladienolide derivative.

Abstract: An apparatus is provided that includes a word line coupled to a word line driver circuit, bit lines, a plurality of non-volatile memory cells each coupled to the word line and a corresponding one of the bit lines, and a control circuit coupled to the word line and the bit lines. The control circuit is configured to program the memory cells by causing the word line driver to apply a program pulse to the word line, and biasing each bit line to a corresponding bit line voltage that has a value that varies based on a distance between the word line driver and the corresponding bit line.

Abstract: The present disclosure provides an ultrasonic radar array, an obstacle detection method and system. The method includes: obtaining obstacle information collected by ultrasonic radars in an ultrasonic radar array in an obstacle scenario; judging false detection and missed detection for the obstacle information collected by ultrasonic radars according a preset rule; processing the obstacle information collected by the ultrasonic radars according to the judgement result; determining a position of the obstacle according to the processed obstacle information collected by the ultrasonic radars.

Abstract: The present disclosure provides a method and system for processing an obstacle detection result of an ultrasonic sensor array. The method comprises: obtaining obstacle coordinates collected by ultrasonic sensors in an ultrasonic sensor array; inputting the obstacle coordinates collected by ultrasonic sensors in the ultrasonic sensor array into a pre-trained neural network model, to obtain true or false labels for the obstacle coordinates collected by the ultrasonic sensors output by the pre-trained neural network model; process the obstacle coordinates collected by the ultrasonic sensors in the ultrasonic sensor array according to the true or false labels. The present disclosure improves the accuracy in the obstacle detection of the ultrasonic sensor array, avoids detection error and omission and improves the driving safety.

Abstract: An adjustment device, an air duct structure, an exhaust system, a dishwasher, and a method for controlling the dishwasher are provided. The adjustment device is applied in an exhaust system. The exhaust system has an exhaust channel with a second air inlet and a first air inlet. The adjustment device includes an adjustment mechanism and a controller. The adjustment mechanism is configured to, under control of the controller, respectively adjust a flow rate of a first gas entering the exhaust channel through the first air inlet and a flow rate of a second gas entering the exhaust channel through the second air inlet, to control a ratio of the first gas entering the exhaust channel to the second gas entering the exhaust channel. Humidity of the second gas is lower than humidity of the first gas.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: Controlling a capacity of the compression system in response to the variable incoming gas feed by: i) selectively varying a capacity of a first subset of one or more of the compressor trains by continuously varying the capacity of one or more cylinders of the one or more reciprocating compressor stages of the one or more compressor trains of the first subset between a maximum capacity and a minimum capacity; and/or ii) selectively varying a capacity of a second subset of one or more of the compressor trains by fully loading or fully unloading one or more cylinders of the one or more reciprocating compressor stages of the compressor trains of the second subset, wherein the first and second subsets are mutually exclusive.

Abstract: An industrial gas production plant operable to produce a feedstock gas at a variable production rate for supply to the downstream process; and a gas storage resource operable to store produced feedstock gas, the method comprising: determining the pressure of feedstock gas in a supply feed line to the downstream process; selectively controlling, using a control system, a flow of feedstock gas from the supply feed line to the gas storage resource or from the gas storage resource to the supply feed line in response to the determined pressure in order to regulate the pressure of the feedstock gas in the supply feed line to the downstream process at a predetermined set point pressure; and selectively controlling, using a control system, a flow rate of feedstock gas in the supply feed line to the downstream process in dependence upon at least one operational parameter of the gas storage resource.

Abstract: Methods, systems, devices, and tangible non-transitory computer readable media for haze reduction are provided. The disclosed technology can include generating feature vectors based on an input image including points. The feature vectors can correspond to feature windows associated with features of different portions of the points. Based on the feature vectors and a machine-learned model, a haze thickness map can be generated. The haze thickness map can be associated with an estimate of haze thickness at each of the points. Further, the machine-learned model can estimate haze thickness associated with the features. A refined haze thickness map can be generated based on the haze thickness map and a guided filter. A dehazed image can be generated based on application of the refined haze thickness map to the input image. Furthermore, a color corrected dehazed image can be generated based on performance of color correction operations on the dehazed image.

Abstract: A broadband terahertz fourth-harmonic mixer circuit, a mixer and a method wherein the broadband terahertz fourth-harmonic mixer circuit includes a radio frequency signal coupled transmission unit, nonlinear device, local oscillator filter, local oscillator signal coupled transmission unit and intermediate frequency filter unit which are sequentially connected; and further includes a radio frequency input port, local oscillator input port and intermediate frequency output port, where the radio frequency input port is connected to the radio frequency signal coupled transmission unit, the local oscillator input port is connected to the local oscillator signal coupled transmission unit, the intermediate frequency output port is connected to an output end of the intermediate frequency filter unit, and the local oscillator filter is of a two-level cascaded filter structure.