Abstract: The disclosure relates to KRASG12D inhibitor compounds having the structure of Formula (A) or Formula (B), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRASG12D mutation-associated diseases, disorders and conditions.

Abstract: A surface treatment method of a material, comprising: respectively immersing a material to be treated into a first inorganic acid solution and a fluoride acidic solution to perform surface etching, so that nano-sized holes are formed in the surface of the material to be treated. Further disclosed are a material product and a composite material.

Abstract: The present disclosure relates to a process of machining a metal middle frame, which includes the following steps of: obtaining a sheet material and cutting the sheet material into a linear profile; performing a finish machining to the linear profile; bending the linear profile after the finish machining, obtaining a metal border frame with an R angle; welding the metal border frame; and placing the metal border frame after the welding in a die-casting mold, providing a die-casting metal liquid, thereby obtaining a die-cast middle plate connected to the metal border frame, so as to form the metal middle frame.

Abstract: Provided is a turning and milling system, comprising: a work platform comprising a first drive mechanism; a rotating platform, said first drive driving said rotating platform to rotate on the said work platform and drive a workpiece to rotate about a vertical axis; a blade assembly comprising a blade and a second drive mechanism connected to the blade; said second drive mechanism drives the blade to move in the horizontal direction, changing the machining radius of the blade.

Abstract: Provided is a riveted metal middle frame including a middle plate and a border frame riveted to the middle plate. The middle plate is made of aluminum alloy, and the periphery of the middle plate is convexly provided with convex edge. The border frame includes members connected end to end in sequence. The members are made of metal material with hardness not less than aluminum alloy, and are riveted to the periphery of the middle plate; and the inner sides of the members are respectively provided with slots for connecting the convex edge. The convex edge is riveted to the slot by press-fitting the border frame. Meanwhile, an electronic device including the above-described riveted metal middle frame is also provided. The beneficial effects are that the middle plate and the border frame are riveted together by press-fitting deformation, thereby improving production efficiency and reducing manufacturing cost.

Abstract: The present disclosure discloses a process of processing a middle frame of a mobile phone, which includes: providing at least two metal components, each of the metal components defining a riveting groove; providing a metal middle plate having a riveting projection at edges thereof; correspondingly mounting each of the metal components on the edges of the metal middle plate to form a border frame surrounding the metal middle plate, respectively; the riveting projection being received in the riveting groove of the metal component, the riveting projection being in clearance fit with the riveting groove; and applying a force to the border frame to deform at least one of the riveting groove and the riveting projection, such that the riveting projection is latched in the riveting groove, and the border frame and the metal middle plate are connected to form the middle frame of the mobile phone.

Abstract: The present disclosure relates to a riveted metal middle frame comprising a middle plate and a border frame riveted to the middle plate. The middle plate is made of aluminum alloy, and the periphery of the middle plate is convexly provided with convex edge. The border frame comprises a plurality of members connected end to end in sequence. The members are made of metal material with hardness not less than aluminum alloy, and the members are riveted to the periphery of the middle plate, and the inner sides of the members are respectively provided with slot for connecting the convex edge. A riveting between the convex edge and the slot may be achieved by press-fitting the border frame. At the same time, an electronic device comprising the above-described riveted metal middle frame is also provided. The beneficial effects of the invention are that the middle plate and the border frame are riveted together by press-fitting deformation, thereby improving production efficiency and reducing manufacturing cost.

Abstract: The present disclosure discloses a process of processing a middle frame of a mobile phone, which includes: providing at least two metal components, each of the metal components defining a riveting groove; providing a metal middle plate having a riveting projection at edges thereof; correspondingly mounting each of the metal components on the edges of the metal middle plate to form a border frame surrounding the metal middle plate, respectively; the riveting projection being received in the riveting groove of the metal component, the riveting projection being in clearance fit with the riveting groove; and applying a force to the border frame to deform at least one of the riveting groove and the riveting projection, such that the riveting projection is latched in the riveting groove, and the border frame and the metal middle plate are connected to form the middle frame of the mobile phone.

Abstract: The present disclosure relates to a process of machining a metal middle frame, which includes the following steps of: obtaining a sheet material and cutting the sheet material into a linear profile; performing a finish machining to the linear profile; bending the linear profile after the finish machining, obtaining a metal border frame with an R angle; welding the metal border frame; and placing the metal border frame after the welding in a die-casting mold, providing a die-casting metal liquid, thereby obtaining a die-cast middle plate connected to the metal border frame, so as to form the metal middle frame.

Abstract: A surface treatment method of a material, comprising: respectively immersing a material to be treated into a first inorganic acid solution and a fluoride acidic solution to perform surface etching, so that nano-sized holes are formed in the surface of the material to be treated. Further disclosed are a material product and a composite material.

Abstract: A middle frame for a mobile phone, includes a middle plate, and an edge of the middle plate forms a latching portion. A boarder frame defining a latching groove on a side thereof facing the middle plate, and the latching portion is riveted in the latching groove. The middle plate and the border frame form a first seam and a second seam on a junction portion and the middle plate and the border frame are provided with a first mounting groove and a second mounting groove. The first seam is located in the first mounting groove, the second seam is located in the second mounting groove. First and second sealing elements, and the first sealing element is filled in the first mounting groove, and the second sealing element is filled in the second mounting groove.

Abstract: A middle frame for a mobile phone, includes a middle plate, and an edge of the middle plate forms a latching portion; a boarder frame defining a latching groove on a side thereof facing the middle plate, and the latching portion is riveted in the latching groove, the middle plate and the border frame form a first seam and a second seam on a junction portion therebetween; and the middle plate and the border frame are provided with a first mounting groove and a second mounting groove therebetween, the first seam is located in the first mounting groove, the second seam is located in the second mounting groove; and first and second sealing elements, and the first sealing element is filled in the first mounting groove, and the second sealing element is filled in the second mounting groove.

Abstract: Provided is a turning and milling system, comprising: a work platform comprising a first drive mechanism; a rotating platform, said first drive driving said rotating platform to rotate on the said work platform and drive a workpiece to rotate about a vertical axis; a blade assembly comprising a blade and a second drive mechanism connected to the blade; said second drive mechanism drives the blade to move in the horizontal direction, changing the machining radius of the blade.