Abstract: The present disclosure relates a method for reducing animal weight, comprising administering to a patient in need thereof a therapeutically or prophylactically effective amount of a mulberry extract. The mulberry extract comprises: 3% to 99% of an alkaloid, 0.2% to 70% of a polysaccharide, 0% to 50% of an amino acid, 0% to 10% of flavone, and 0% to 25% of other components. The mulberry extract of the present disclosure can be used for controlling weight gain, and has a good therapeutic effect on type 2 diabetes with obesity.

Abstract: The present invention discloses a sludge anaerobic fermentation treatment method with simultaneously enhanced acid production and phosphorus removal. The method includes steps of: (1) adding waste activated sludge into an anaerobic reaction system, with a concentration of a total suspended solid (TSS) of 10000-15000 mg/L; (2) maintaining a pH value of the waste activated sludge at 10±0.1; adding powdery magnetite of 0.3-0.9 g/gVS S. Compared with simple alkaline conditions, in the method of the present invention, an accumulation amount of short chain fatty acids (SCFAs) in a fermentation broth is increased by 20%, and a content of orthophosphoric acid is reduced by 10%. The method can further improve the enhancing effect by using sulfuric acid to modify the magnetite, the accumulation amount of SCFAs can be increased by 36.7% at most, and the content of phosphorus and refractory organic substances can be reduced by 32.4% and 40.4% at most, respectively.

Abstract: The disclosure relates to the field of medicinal chemistry. Disclosed are a 14-chloro-?-elemene nitric oxide donor derivative and a preparation method and use thereof in the preparation of anti-tumor drugs. The 14-chloro-?-elemene nitric oxide donor derivative has a general formula shown in formula (I): in formula (I): R1 represents a linear or cyclic alcohol amine structure containing nitrogen and oxygen atoms; and each of R2 and R3 is independently selected from the group consisting of C1-10 alkyl, C3-12 cycloalkyl, C6-12 aryl, 5- to 10-membered cyclic heteroaryl, C2-10 alkenyl, C2-10 alkynyl, and C2-10 alkoxy.

Abstract: Disclosed are a method and system for generating a virtual boundary of a working region of a self-moving robot, and a self-moving robot and a readable storage medium.

Abstract: Provided is an isolated antigen-binding protein, which can specifically bind to CD73 and includes at least one CDR in a heavy chain variable region VH, wherein the region VH includes an amino acid sequence as represented by SEQ ID NO: 49.

Abstract: A packet forwarding method, an electronic device, and a storage medium are disclosed. The method may include: determining a flow identifier of the service flow; determining a basic time slot number of a first packet in the service flow according to the flow identifier; determining a time slot offset of the first node for the service flow according to the flow identifier; and determining an enqueue slot number of the first packet according to the basic time slot number and the time slot offset.

Abstract: Provided is an isolated antigen-binding protein, capable of binding to CD73. The isolated antigen-binding protein contains HCDR3, and the HCDR3 comprises an amino acid sequences as shown in SEQ ID No.:3. Also provided are a preparation method for the antigen-binding protein, and an application of the antigen-binding protein.

Abstract: Provided in the present application are an anti-PD-L1/TGF-? bispecific antibody and the use thereof. Specifically, provided in the present application is a bifunctional antibody, which comprises: (a) an anti-PD-L1 antibody or element; and (b) an anti-TGF-? antibody or element connected to the anti-PD-L1 antibody or element. The bifunctional antibody of the present application can simultaneously bind to TGF-? and PD-L1, thereby exerting a therapeutic effect on TGF-? and PD-L1-positive tumor cells.

Abstract: Provided in the present application is a multispecific antibody, which includes a first targeting moiety capable of specifically binding to the TIGIT protein and a second targeting moiety capable of binding to a tumor-associated antigen, and the multispecific antibody can be used to treat a tumor. Further provided in the present application is the use of the multispecific antibody as a drug.

Abstract: An apparatus to simulate biocide performance in crude oil pipeline conditions is disclosed. The apparatus includes: a reactor to simulate a two-phase crude oil pipeline which includes a crude oil phase above a water phase. The reactor has an agitator to control a flow of the water phase in the reactor in response to a motor that drives an agitation rate of the agitator. A crude oil inlet supplies crude oil to the reactor for the crude oil phase. A water inlet supplies water to the reactor for the water phase. A control circuit is configured by code to control a proportion of the water to the crude oil supplied to the reactor and to control the motor to drive a desired agitation rate of the agitator. A biocide inlet supplies biocide to the reactor. A water sample outlet enables sampling of the water phase of the reactor.

Abstract: The present disclosure provides a message forwarding method, including: receiving a target message from an upstream device, the target message carrying first timeslot information including a first timeslot length and a first timeslot identifier; determining a second timeslot length and a second timeslot identifier according to the first timeslot length and the first timeslot identifier; and in response to that a preset waiting time elapses after the target message enters a cache queue corresponding to the second timeslot length and the second timeslot identifier, forwarding the target message. The present disclosure further provides a message forwarding device, and a computer-readable medium.

Abstract: A plant extraction method includes the following steps: 1) preparation of a crude plant extraction solution; 2) separation of the crude extraction solution through a cation resin and an optional anion resin to obtain a collection solution; 3) concentration of the collection solution obtained in step 2); 4) alcohol precipitation of the concentration solution obtained in step 3); and optionally, step 5) concentration and drying. The method can effectively reduce the content of heavy metals in an extract, and reduce the amount of ethanol used in extraction, thereby improving the product quality and lowering the production cost, and the efficiency and safety of industrial production are improved. The extract obtained by this method can be used to prepare drugs for lowering blood lipid, treating abnormal glucose tolerance, treating diseases related to abnormal blood glucose, or regulating intestinal flora, and can be processed into food products, health-care products or drinks.

Abstract: The present application provides a redundant path resource reservation method, a network device, and a storage medium. The method includes: acquiring, from a received attribute declaration packet of a talker device, a TSN service targeted by the attribute declaration packet and an indication of whether to provide redundant propagation for the attribute declaration packet; duplicating the attribute declaration packet in response to the indication of providing the redundant propagation for the attribute declaration packet, and there are at least two spanning tree instances maintained in a bridge device; propagating the received attribute declaration packet and the duplicated attribute declaration packet, to establish a redundant path for the TSN service between the talker device and a listener device; and performing, in response to receiving a resource reservation request packet for the TSN service from the listener device, redundant path resource reservation for the TSN service.

Abstract: An apparatus to simulate biocide performance in crude oil pipeline conditions is disclosed. The apparatus includes: a reactor to simulate a two-phase crude oil pipeline which includes a crude oil phase above a water phase. The reactor has an agitator to control a flow of the water phase in the reactor in response to a motor that drives an agitation rate of the agitator. A crude oil inlet supplies crude oil to the reactor for the crude oil phase. A water inlet supplies water to the reactor for the water phase. A control circuit is configured by code to control a proportion of the water to the crude oil supplied to the reactor and to control the motor to drive a desired agitation rate of the agitator. A biocide inlet supplies biocide to the reactor. A water sample outlet enables sampling of the water phase of the reactor.

Abstract: Systems and methods for a lithium-ion battery cell are disclosed. In one example, a method for forming a cathode for a lithium-ion battery cell includes forming a pre-lithiated cathode with a pre-lithiation reagent and positioning the pre-lithiated cathode in contact with an electrolyte. An electrolyte additive is injected into the electrolyte to form a passivation layer at the pre-lithiated cathode, the passivation layer inhibiting continued decomposition of the pre-lithiation reagent of the pre-lithiated cathode after completion of a formation cycle of the lithium-ion battery cell.

Abstract: Provided is a separated antigen-binding protein. The antigen-binding protein comprises at least one CDR in a heavy chain variable region VH, and the VH comprises an amino acid sequence shown in SEQ ID NO: 55. Also provided are an anti-TIGIT antibody, and a preparation method and an application thereof. The antigen-binding protein can specifically bind with a TIGIT antigen to block the binding of TIGIT and a ligand thereof, and can be used for preparing drugs for preventing or treating TIGIT-related diseases.

Abstract: The present application relates to the field of network communication technologies, and provides a packet processing method and device, an advertisement method and device, a bridge node, a source apparatus, a packet processing system, and a computer-readable storage medium. The packet processing method includes: receiving a time sensitive networking (TSN) service packet; querying, according to a packet header of the TSN service packet, a mapping table of service stream IDs and TSN-profiles, where the mapping table of service stream IDs and TSN-profiles is established according to advertisement information of a source apparatus; and processing the TSN service packet according to a result of the querying on the mapping table of service stream IDs and TSN-profiles.

Abstract: The embodiments of the present disclosure provide a data packet processing method and apparatus, a storage medium and an electronic device. The method includes that: a Bit Index Explicit Replication (BIER) Multicast Identifier (BMID) information of a data packet is set, wherein the BMID information is used for indicating a multicast channel to which the data packet belongs; and the BMID information is sent to a Bit-Forwarding Ingress Router (BFIR). Through the solution in the embodiments of the present disclosure, the technical problem in the related art that a node receives duplicate data packets is solved, duplicate data packets may be prevented, and data transmission efficiency is improved.

Abstract: A port resource reservation method, an electronic device, and a storage medium are disclosed. The method may include, receiving a request message for reserving a resource for traffic, and determining a mode for resource reservation according to the request message; in response to a determination that resource reservation is to be performed in an extended mode, acquiring, according to a predetermined first mapping relationship, an egress port queue corresponding to an extended priority carried in the request message, and performing resource reservation for the traffic on the egress port queue corresponding to the extended priority, wherein the first mapping relationship refers to a mapping relationship between the extended priority and the egress port queue; and acquiring a traffic identifier from the request message, and establishing a second mapping relationship, wherein the second mapping relationship refers to a mapping relationship between the traffic identifier and the extended priority.

Abstract: An apparatus for in-situ monitoring and measuring of general corrosion and localized microbiologically influenced corrosion (MIC) in a simulated environment is provided. The apparatus includes a chamber containing an electrolyte solution and a microbe specimen. The chamber includes a pair of electrical resistance (ER) probes that measure a current flowing through the electrolyte solution and a general corrosion rate on the surface of the ER probes. The chamber also includes a pair of electrochemical noise (EN) probes. The EN probes are aligned to face one another such that the EN probes measure a localized corrosion rate on the surface of the EN probes and measure the influence of gravity on MIC. The apparatus measures the general and localized corrosion rates simultaneously without polarizing the surface of the ER and EN probes.