Patents by Inventor Xiangyu HE

Xiangyu HE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240177435
    Abstract: The present application provides a method, apparatus, device and medium for virtual interaction, wherein the method includes: presenting a media content stream in a virtual space, wherein the media content stream includes at least one interactive object; switching a current camera position to a target camera position according to interactive indication information; presenting an interactive trigger zone and the interactive object in interactive space of the target camera position; and interacting with the interactive object according to the interactive trigger zone. The present application makes interactive operations of the user in the virtual space more vivid and rich, and thus enhances interactivity of the user in the virtual space and improves interactive quality of the virtual interaction.
    Type: Application
    Filed: November 30, 2023
    Publication date: May 30, 2024
    Inventors: Lichen Huang, Xiangyu Huang, Liyue Ji, Pingfei Fu, Fan Yang, Yixin Sun, Li Lu, Hongxiao Pang, Cheng Zeng, Jingqi Qin, Tan He, Qiang Chen, Jinping Xu, Kang Li
  • Publication number: 20230312704
    Abstract: Provided are an antibody against claudin 18.2 (CLDN18.2) and a use thereof in diagnosing and treating cancer of the stomach, pancreas and esophagus.
    Type: Application
    Filed: February 10, 2021
    Publication date: October 5, 2023
    Inventors: Qing Zhou, Chuanying Xu, Weihong Nian, Xiangyu He, Xinmin Zhang, Xintong Zheng, Feng He, Jing Xiao
  • Publication number: 20230171667
    Abstract: A terminal roaming method, an apparatus, and a wireless local area network are disclosed, and belong to the field of WLAN technologies. A session parameter used when a terminal performs data exchange with an original associated AP is migrated to a roaming target AP. After the terminal is associated with the roaming target AP, the roaming target AP can continue data exchange with the terminal based on the migrated session parameter, and the terminal can also continue data exchange with the roaming target AP based on the session parameter used when the terminal performs data exchange with the original associated AP. The terminal and the roaming target AP do not need to perform session negotiation again, to shorten a data service recovery time required after a roaming handover of the terminal, and reduce a service transmission delay. This improves smoothness of roaming handover of the terminal.
    Type: Application
    Filed: November 28, 2022
    Publication date: June 1, 2023
    Inventors: Shuaishuai Zhang, Baokun Ding, Chun Pan, Xiangyu He, Rihai Wu, Liangliang Chen
  • Publication number: 20230096452
    Abstract: The present invention relates to a claudin 18.2 (CLDN18.2) antibody and the use thereof in treating cancers, such as gastric cancer, pancreatic cancer, and esophageal cancer.
    Type: Application
    Filed: February 10, 2021
    Publication date: March 30, 2023
    Inventors: Qing Zhou, Chuanying Xu, Weihong Nian, Xiangyu He, Xintong Zheng, Xinmin Zhang, Feng He, Jing Xiao
  • Publication number: 20230086530
    Abstract: The present application relates to an anti-CD47 single-domain antibody and a use thereof, and a method for preparing the antibody. The single-domain antibody comprises a CDR selected from the following CDRs: (1) CDR1, CDR2, and CDR3 shown by SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO:3; or (2) CDR1, CDR2, and CDR3 shown by SEQ ID NO: 6, SEQ ID NO: 7, and SEQ ID NO: 8.
    Type: Application
    Filed: February 10, 2021
    Publication date: March 23, 2023
    Inventors: Xiangyu He, Weihong Nian, Chuanying Xu, Xintong Zheng, Xinmin Zhang, Jing Xiao, Feng He, Qing Zhou
  • Patent number: 10227324
    Abstract: Disclosed is a 2-morpholin-4,6-disubstituted pyrimidine derivative as shown in formula (1) below, and a pharmaceutically acceptable salt, solvate, stereoisomer or prodrug thereof, and a pharmaceutical composition thereof and a use thereof, wherein the definition of each group is as shown in the description. The compound has a PI3K kinase inhibition activity, and has a relatively high inhibitive ability and a low cytotoxicity against PIK3CA mutant breast cancer cell strains T47D and MCF-7.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: March 12, 2019
    Assignees: SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD., YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Sida Shen, Xiaojing Ni, Zhiyuan Zhang, Zheng Yang, Xiangyu He, Weiwei Wang, Fusheng Zhou
  • Patent number: 10085983
    Abstract: Azabicyclo derivatives, a preparation process, and medical use thereof are provided. In particular, azabicyclo derivatives of formula (I), pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs thereof are described. The azabicyclo derivatives of formula (I) are useful as Epidermal Growth Factor Receptor (EGFR) inhibitors. The definitions of the variable R groups in the azabicyclo derivatives of formula (I) are described in the specification.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: October 2, 2018
    Assignees: Shanghai Haiyan Pharmaceutical Technology Co., Ltd., Yangtze River Pharmaceutical Group Co., Ltd.
    Inventors: Yunzhou Jin, Ping Bu, Qi He, Jiong Lan, Fusheng Zhou, Liang Zhang, Xiangyu He
  • Patent number: 9890168
    Abstract: The present invention relates to a 2,4-disubstituted 7H-pyrrolo[2,3-d]pyrimidine derivative, a preparation method and a medicinal use thereof. In particular, the present invention discloses a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and use thereof. For the definition of each group in formula (I), see the description tbr details.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: February 13, 2018
    Assignees: Shanghai Haiyan Pharmaceutical Technology Co., Ltd., Yangtze River Pharmaceutical Group Co., Ltd.
    Inventors: Jiong Lan, Yunzhou Jin, Fusheng Zhou, Jing Lei, Chong Wen, Zhiyuan Zhang, Xiangyu He
  • Patent number: 9879008
    Abstract: The present invention relates to 2,3,4,6-tetra-substituted benzene-1,5-diamine derivatives, a preparation method therefor and a medicinal use thereof. Specifically, disclosed are compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs, preparation method therefor and application thereof. Definition of each group in the formula can be found in the specification for details.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: January 30, 2018
    Assignees: SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD., YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Jiong Lan, Yunzhou Jin, Fusheng Zhou, Qi He, Xiangyu He, Qiang Lv
  • Publication number: 20170349568
    Abstract: Disclosed is a 2-morpholin-4,6-disubstituted pyrimidine derivative as shown in formula (1) below, and a pharmaceutically acceptable salt, solvate, stereoisomer or prodrug thereof, and a pharmaceutical composition thereof and a use thereof, wherein the definition of each group is as shown in the description. The compound has a PI3K kinase inhibition activity, and has a relatively high inhibitive ability and a low cytotoxicity against PIK3CA mutant breast cancer cell strains T47D and MCF-7.
    Type: Application
    Filed: December 17, 2015
    Publication date: December 7, 2017
    Inventors: Sida SHEN, Xiaojing NI, Zhiyuan ZHANG, Zheng YANG, Xiangyu HE, Weiwei WANG, Fusheng ZHOU
  • Publication number: 20170296537
    Abstract: Azabicyclo derivatives, a preparation process, and medical use thereof are provided. In particular, azabicyclo derivatives of formula (I), pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs thereof are described. The azabicyclo derivatives of formula (I) are useful as Epidermal Growth Factor Receptor (EGFR) inhibitors. The definitions of the variable R groups in the azabicyclo derviatives of formula (I) are described in the specification.
    Type: Application
    Filed: September 24, 2015
    Publication date: October 19, 2017
    Inventors: Yunzhou JIN, Ping BU, Qi HE, Jiong LAN, Fusheng ZHOU, Liang ZHANG, Xiangyu HE
  • Publication number: 20170233395
    Abstract: The present invention relates to a 2,4-disubstituted 7H-pyrrolo[4,3-d]pyrimidin derivative, a preparation method and a medicinal use thereof. In particular, the present invention discloses a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and use thereof. For the definition of each group in formula (I), see the description tbr details.
    Type: Application
    Filed: July 24, 2015
    Publication date: August 17, 2017
    Inventors: Jiong LAN, Yunzhou JIN, Fusheng ZHOU, Jing LEI, Chong WEN, Zhiyuan ZHANG, Xiangyu HE
  • Publication number: 20170057957
    Abstract: The present invention relates to 2,3,4,6-tetra-substituted benzene-1,5-diamine derivatives, a preparation method therefor and a medicinal use thereof. Specifically, disclosed are compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs, preparation method therefor and application thereof. Definition of each group in the formula can be found in the specification for details.
    Type: Application
    Filed: April 13, 2015
    Publication date: March 2, 2017
    Inventors: Jiong LAN, Yunzhou JIN, Fusheng ZHOU, Qi HE, Xiangyu HE, Qiang LV