Patents by Inventor Xianyan Wang
Xianyan Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11883650Abstract: A implantable neural electrode assembly is described. The implantable neural electrode assembly includes a plurality of open-ended rings alternatingly connected to a spine. An inner layer of the open-ended rings is formed from a drug-loaded material (e.g., silicone that has been loaded with a steroid) and an outer layer is formed from a drug-free material. One or more electrode assemblies are connected to the inner layer and oriented towards a center of a cylinder defined by the plurality of open-ended rings.Type: GrantFiled: June 23, 2020Date of Patent: January 30, 2024Assignee: Verily Life Sciences, LLCInventors: Xianyan Wang, Cindy Au
-
Publication number: 20230346266Abstract: Examples of invasive biosensor alignment and retention features and methods are described. One example biosensor includes a housing comprising: a first surface defining a first opening, and a second surface opposite the first surface, the second surface defining a second opening, the first and second openings defining a substantially unobstructed pathway through the housing; a biosensor wire partially disposed within the housing and having an exterior portion extending through the first opening; a hollow insertion needle positioned within the pathway and extending through the first opening, the hollow insertion needle at least partially encircling the biosensor wire; and a biosensor retention feature collapsible against the first surface of the housing, the biosensor retention feature encircling and contacting the hollow insertion needle.Type: ApplicationFiled: June 26, 2023Publication date: November 2, 2023Inventors: Arthur Lin, Xianyan Wang, Pey-Jiun Ko
-
Patent number: 11717193Abstract: Examples of invasive biosensor alignment and retention features and methods are described. One example biosensor includes a housing comprising: a first surface defining a first opening, and a second surface opposite the first surface, the second surface defining a second opening, the first and second openings defining a substantially unobstructed pathway through the housing; a biosensor wire partially disposed within the housing and having an exterior portion extending through the first opening; a hollow insertion needle positioned within the pathway and extending through the first opening, the hollow insertion needle at least partially encircling the biosensor wire; and a biosensor retention feature collapsible against the first surface of the housing, the biosensor retention feature encircling and contacting the hollow insertion needle.Type: GrantFiled: February 2, 2021Date of Patent: August 8, 2023Assignee: DexCom, Inc.Inventors: Arthur Lin, Xianyan Wang, Pey-Jiun Ko
-
Publication number: 20230233118Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.Type: ApplicationFiled: March 28, 2023Publication date: July 27, 2023Inventors: Ohseung KWON, Xianyan Wang, Timothy Stowe
-
Patent number: 11642054Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.Type: GrantFiled: June 2, 2020Date of Patent: May 9, 2023Assignee: DexCom, Inc.Inventors: Ohseung Kwon, Xianyan Wang, Timothy Stowe
-
Publication number: 20210290163Abstract: Examples of invasive biosensor alignment and retention features and methods are described. One example biosensor includes a housing comprising: a first surface defining a first opening, and a second surface opposite the first surface, the second surface defining a second opening, the first and second openings defining a substantially unobstructed pathway through the housing; a biosensor wire partially disposed within the housing and having an exterior portion extending through the first opening; a hollow insertion needle positioned within the pathway and extending through the first opening, the hollow insertion needle at least partially encircling the biosensor wire; and a biosensor retention feature collapsible against the first surface of the housing, the biosensor retention feature encircling and contacting the hollow insertion needle.Type: ApplicationFiled: February 2, 2021Publication date: September 23, 2021Inventors: Arthur Lin, Xianyan Wang, Pey-Jiun Ko
-
Patent number: 10932699Abstract: Examples of invasive biosensor alignment and retention features and methods are described. One example biosensor includes a housing comprising: a first surface defining a first opening, and a second surface opposite the first surface, the second surface defining a second opening, the first and second openings defining a substantially unobstructed pathway through the housing; a biosensor wire partially disposed within the housing and having an exterior portion extending through the first opening; a hollow insertion needle positioned within the pathway and extending through the first opening, the hollow insertion needle at least partially encircling the biosensor wire; and a biosensor retention feature collapsible against the first surface of the housing, the biosensor retention feature encircling and contacting the hollow insertion needle.Type: GrantFiled: September 13, 2017Date of Patent: March 2, 2021Assignee: DEXCOM, INC.Inventors: Arthur Lin, Xianyan Wang, Pey-Jiun Ko
-
Publication number: 20200297254Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.Type: ApplicationFiled: June 2, 2020Publication date: September 24, 2020Inventors: Ohseung Kwon, Xianyan Wang, Timothy Stowe
-
Patent number: 10709384Abstract: Wearable heat flux devices are disclosed that can detect heat flux based on evaporative cooling for determining a core body temperature of a user, and that can heat or cool a surface of a user for reaching a steady-state heat flux to determine the core body temperature of the user. Exemplary heat flux devices can include a heat flux sensor and a wicking layer. The heat flux sensor can be configured to detect heat flux at a location on a user. The wicking layer can be configured to absorb moisture at the location and to transport the moisture above the heat flux sensor. The heat flux subsequently detected by the heat flux sensor includes the evaporative cooling from the evaporation of the moisture.Type: GrantFiled: August 16, 2016Date of Patent: July 14, 2020Assignee: MC10, INC.Inventors: Hoi-Cheong Steve Sun, Milan Raj, Xianyan Wang, Brian Murphy, Valerie Susan Hanson
-
Patent number: 10702198Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.Type: GrantFiled: November 29, 2016Date of Patent: July 7, 2020Assignee: DexCom, Inc.Inventors: Ohseung Kwon, Xianyan Wang, Timothy Stowe
-
Patent number: 10653332Abstract: A device includes a flexible printed circuit board and one or more conductive stiffeners. The conductive stiffeners include a conductive surface that can be electrically connected to contact pads on the flexible printed circuit board. The wearable device can further include an adhesive layer or an encapsulation layer. The adhesive layer and the encapsulation layer can include conductive portions surrounded by non-conductive portions. The conductive portions can be aligned with the conductive stiffeners and together transmit electrical energy to the contact pads of the flexible printed circuit board.Type: GrantFiled: July 12, 2016Date of Patent: May 19, 2020Assignee: MC10, Inc.Inventors: Bryan McGrane, Milan Raj, PingHung Wei, Briana Morey, Roozbeh Ghaffari, Monica Lin, Jeffrey Model, Xianyan Wang, Bryan Keen, Stephen Lee
-
Patent number: 10410962Abstract: Encapsulated conformal electronic devices, encapsulated conformal integrated circuit (IC) sensor systems, and methods of making and using encapsulated conformal electronic devices are presented herein. A conformal integrated circuit device is disclosed which includes a flexible substrate with electronic circuitry attached to the flexible substrate. A flexible encapsulation layer is attached to the flexible substrate. The flexible encapsulation layer encases the electronic circuitry between the flexible substrate and the encapsulation layer. For some configurations, the encapsulation layer and flexible substrate arc fabricated from stretchable and bendable non-conductive polymers. The electronic circuitry may comprise an integrated circuit sensor system with multiple device islands that are electrically and physically connected via a plurality of stretchable electrical interconnects.Type: GrantFiled: January 6, 2015Date of Patent: September 10, 2019Assignee: MC10, Inc.Inventors: Nicholas McMahon, Xianyan Wang, Brian Elolampi, Bryan D. Keen, David G. Garlock
-
Publication number: 20190076069Abstract: Examples of invasive biosensor alignment and retention features and methods are described. One example biosensor includes a housing comprising: a first surface defining a first opening, and a second surface opposite the first surface, the second surface defining a second opening, the first and second openings defining a substantially unobstructed pathway through the housing; a biosensor wire partially disposed within the housing and having an exterior portion extending through the first opening; a hollow insertion needle positioned within the pathway and extending through the first opening, the hollow insertion needle at least partially encircling the biosensor wire; and a biosensor retention feature collapsible against the first surface of the housing, the biosensor retention feature encircling and contacting the hollow insertion needle.Type: ApplicationFiled: September 13, 2017Publication date: March 14, 2019Inventors: Arthur Lin, Xianyan Wang, Pey-Jiun Ko
-
Publication number: 20180146894Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.Type: ApplicationFiled: November 29, 2016Publication date: May 31, 2018Inventors: Ohseung Kwon, Xianyan Wang, Timothy Stowe
-
Publication number: 20180111353Abstract: The present invention describes multilayered adhesive structures that can be used as adhesives to mount wearable devices onto the skin. The multilayered adhesive structures can comprise a buffer layer sandwiched between two adhesive layers, a first adhesive layer adhering the multilayered adhesive structure to the wearable device and a second adhesive layer adhering the buffer layer to the skin. The buffer layer separates or isolates the wearable device from the skin. By mechanically buffering the wearable device from the skin, the multilayered adhesive structures permit the devices to be skin-mounted for an extended period of time (e.g., a few hours or days) without causing moisture-associated skin injuries such as erythema, maceration, and irritation or inflammation.Type: ApplicationFiled: December 21, 2017Publication date: April 26, 2018Inventors: Gilbert Lee Huppert, Xianyan Wang, Roozbeh Ghaffari, Pinghung Wei, Ji Hyung Suzy Hong, Hakan Mutlu, Brian Murphy, David G. Garlock
-
Patent number: 9808557Abstract: Described are tubular silk fibroin compositions and methods for their manufacture and use. Tubular compositions as described herein can be produced in a range of high burst strengths, can easily be made in a range of inner diameters, can be derivatized with functional moieties, and can be produced in a range of permeabilities suitable for particularized uses. In one aspect, the tubular compositions can be used in the repair or replacement of damaged or diseased blood vessels, including, but not limited to vessels smaller than about 6 mm.Type: GrantFiled: August 11, 2008Date of Patent: November 7, 2017Assignees: Trustees of Tufts College, The Trustees of Columbia University in the City of New York, Massachussets Institute of TechnologyInventors: Michael L. Lovett, Xianyan Wang, Christopher M. Cannizzaro, Gordana Vunjak-Novakovic, David L. Kaplan
-
Patent number: 9731052Abstract: The invention provides a method for the controlled assembly of layered silk fibroin coatings using aqueous silk fibroin material. The methods described herein can be used to coat substrates of any material, shape, or size. Importantly, the described methods enable control of the biomaterial surface chemistry, thickness, morphology and structure using layered thin film coatings, or bulk coatings. Furthermore, the methods can be performed in all water and do not require intensive chemical processing enabling controlled entrapment of labile molecules such as, drugs, cytokines, and even cells or viruses to generate functional coatings that can be used in a variety of applications.Type: GrantFiled: May 6, 2015Date of Patent: August 15, 2017Assignee: Trustees of Tufts CollegeInventors: David L. Kaplan, Xianyan Wang
-
Publication number: 20170049397Abstract: Wearable heat flux devices are disclosed that can detect heat flux based on evaporative cooling for determining a core body temperature of a user, and that can heat or cool a surface of a user for reaching a steady-state heat flux to determine the core body temperature of the user. Exemplary heat flux devices can include a heat flux sensor and a wicking layer. The heat flux sensor can be configured to detect heat flux at a location on a user. The wicking layer can be configured to absorb moisture at the location and to transport the moisture above the heat flux sensor. The heat flux subsequently detected by the heat flux sensor includes the evaporative cooling from the evaporation of the moisture.Type: ApplicationFiled: August 16, 2016Publication date: February 23, 2017Inventors: Hoi-Cheong Steve Sun, Milan Raj, Xianyan Wang, Brian Murphy, Valerie Susan Hanson
-
Publication number: 20170019988Abstract: A wearable device includes a flexible printed circuit board and one or more conductive stiffeners. The conductive stiffeners include a conductive surface that can be electrically or thermally connected to contact pads on the flexible printed circuit board. The wearable device can further include an adhesive layer or an encapsulation layer. The adhesive layer and the encapsulation layer can include conductive portions surrounded by non-conductive portions. The conductive portions can be aligned with the conductive stiffeners and together transmit electrical and/or thermal energy to the contact pads of the flexible printed circuit board.Type: ApplicationFiled: July 12, 2016Publication date: January 19, 2017Inventors: Bryan McGrane, Milan Raj, PingHung Wei, Briana Morey, Roozbeh Ghaffari, Monica Lin, Jeffrey Model, Xianyan Wang, Bryan Keen, Stephen Lee
-
Publication number: 20160361015Abstract: The present invention describes breathable multilayered adhesive structures that can be used as adhesives to mount devices onto the skin. The breathable multilayered adhesive structures can comprise moisture-wicking layers adhered to the skin by a porous adhesion layer. The pores allow moisture released from the skin to be transferred away through the moisture-wicking layer. The adhesive structures permit the devices to be skin-mounted for an extended period of time (e.g., a few hours or days) without causing moisture-associated skin injuries such as erythema, maceration, and irritation or inflammation.Type: ApplicationFiled: June 15, 2016Publication date: December 15, 2016Inventors: Xianyan Wang, Roozbeh Ghaffari, Pinghung Wei, Ji Hyung Suzy Hong, Hakan Mutlu, Brian Murphy, David G. Garlock