Patents by Inventor Xiaoqun ZHAO

Xiaoqun ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240076701
    Abstract: Provided are a recombinant strain with modified gene BBD29_14900, and a method for constructing the same and use thereof, with the production of L-glutamic acid as a specific application. Further provided is a method for introducing a point mutation into the BBD29_14900 gene coding sequence in Corynebacterium or improving the expression thereof. The method can cause a bacterial strain with the mutation to increase the fermentation yield of glutamic acid. The point mutation involves a mutation of the base at position 1114 in the sequence of the BBD29_14900 gene from guanine (G) to adenine (A), and thus a substitution of aspartic acid at position 372 in the coded corresponding amino acid sequence with asparagine.
    Type: Application
    Filed: December 29, 2022
    Publication date: March 7, 2024
    Applicant: NINGXIA EPPEN BIOTECH CO., LTD
    Inventors: Fengyong MA, Aiying WEI, Gang MENG, Chunguang ZHAO, Huiping JIA, Houbo SU, Lipeng YANG, Xiaowei GUO, Bin TIAN, Xiaoqun ZHOU
  • Publication number: 20240067998
    Abstract: Disclosed are strain having enhanced L-glutamic acid production capacity, and method for constructing the same and use thereof. A nucleotide sequence is provided by introducing a point mutation to a wild-type BBD29-00405 gene in Corynebacterium glutamicum so that the base at position 597 of SEQ ID NO: 1 is mutated from guanine (G) into adenine (A). Also provided is a recombinant strain obtained by introducing the polynucleotide sequence into L-glutamic acid-producing Corynebacterium glutamicum, the recombinant strain comprising a BBD29-00405 gene containing a point mutation. Compared with an unmodified strain, the resulting strain facilitates production of L-glutamic acid at a higher concentration.
    Type: Application
    Filed: December 29, 2021
    Publication date: February 29, 2024
    Applicant: NINGXIA EPPEN BIOTECH CO., LTD
    Inventors: Houbo SU, Aiying WEI, Gang MENG, Lipeng YANG, Fengyong MA, Huiping JIA, Xiaoqun ZHOU, Chunguang ZHAO
  • Publication number: 20240067999
    Abstract: A recombinant strain with modified gene BBD29_11265 and a method for constructing the same are provided. The recombinant strain is a bacterium that generates L-glutamic acid, and has an improved expression of a polynucleotide encoding an amino acid sequence of SEQ ID NO: 3 or a homologous sequence thereof; the improved expression can be having a point mutation in, and an enhanced expression of the polynucleotide encoding an amino acid sequence of SEQ ID NO: 3 or a homologous sequence thereof. A genetically engineered bacterium in which the base at position 70 in the BBD29_112665 gene sequence is mutated to adenine from guanine, causing alanine at position 24 in the coded corresponding amino acid sequence to be substituted with threonine, and an engineered bacterium overexpressing the BBD29_112665 gene or BBD29_11265G70A gene are constructed in the present invention, facilitating an increase in the production and conversion rate of L-glutamic acid.
    Type: Application
    Filed: December 28, 2021
    Publication date: February 29, 2024
    Applicant: NINGXIA EPPEN BIOTECH CO., LTD
    Inventors: Aiying WEI, Gang MENG, Chunguang ZHAO, Huiping JIA, Houbo SU, Lipeng YANG, Xiaowei GUO, Bin TIAN, Fengyong MA, Xiaoqun ZHOU
  • Publication number: 20140164002
    Abstract: A Joint Source-Channel Decoding (JSCD) apparatus, method, necessity judging method, and a receiver includes: a source coding rate change judging unit configured to judge whether a source coding rate of the current frame is the same as the previous frame; a source coding rate eligibility judging unit configured to judge whether the source coding rate of the current frame is less than a predetermined source coding rate threshold; a current frame SIR eligibility judging unit configured to judge whether an SIR of the current frame is lower than a predetermined SIR threshold, a necessity result determining unit configured to determine that a JSCD is necessary, when the source coding rate of the current frame is the same as the previous frame, the source coding rate of the current frame is less than the source coding rate threshold, and the SIR of the current frame is lower than the SIR threshold.
    Type: Application
    Filed: November 26, 2013
    Publication date: June 12, 2014
    Applicant: FUJITSU LIMITED
    Inventors: Lei ZHANG, Xin WANG, Hua ZHOU, Jianming WU, Xiaolei HAN, Xiaoqun ZHAO, Nan ZHANG, Tenglong FANG