Patents by Inventor Xiaohe Liu
Xiaohe Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230393140Abstract: An example binding assay includes a plurality of sub-regions, a plurality of synthetic compounds on beads, wherein each of the plurality of sub-regions includes one of the plurality of synthetic compounds, a biological target labeled with a first detectable label in each of the plurality sub-regions, and a biological counter target labeled with a second detectable label in each of the plurality of sub-regions. The biological counter target is configured to bind to the biological target when the biological target is in a first orientation. And, wherein a first subset of the plurality of synthetic compounds bind to the biological target and effect interactions between the biological target and the biological counter target.Type: ApplicationFiled: October 15, 2021Publication date: December 7, 2023Applicant: SRI InternationalInventors: Peter Madrid, Nathan Collins, Michal Avital-Shmilovici, Xiaohe Liu, Thomas Shaler
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Publication number: 20230298021Abstract: A method for acquiring a random number for a blockchain includes: in a process of executing a business transaction request, calling an oracle contract to generate a random number acquisition request; processing the random number acquisition request through the oracle contract, and making at least two oracle nodes arranged outside the blockchain generate random factors based on private keys of the at least two oracle nodes; acquiring the random factors fed back by the at least two oracle nodes through the oracle contract; aggregating the random factors through the oracle contract to form an aggregation factor, and generating a random number according to the aggregation factor and an on-chain random algorithm; and feeding back the random number to the business transaction request through the oracle contract.Type: ApplicationFiled: March 14, 2023Publication date: September 21, 2023Inventor: Xiaohe LIU
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Publication number: 20230297557Abstract: Provided are a method and apparatus for monitoring a state of an external data source, a device, and a medium, relating to the field of computer technology and, in particular, to blockchain technology. The method is applied by a blockchain node and includes acquiring a data subscription transaction request initiated by a client; invoking an oracle contract to perform the data subscription transaction request to record a target data subject subscribed by a user and control an oracle node to monitor a change of target data of the target data subject provided by the external data source; acquiring a change event of the target data subject fed back by the oracle node and uploading the change event to a chain to enable the client to monitor the change event. The preceding technical solution implements the monitoring of the state change of the external data source.Type: ApplicationFiled: March 15, 2023Publication date: September 21, 2023Inventor: Xiaohe LIU
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Patent number: 11349638Abstract: Embodiments of the present disclosure provide a privacy transaction processing method, an electronic device and a storage medium, and relates to a field of blockchain technologies. The method includes: obtaining a business transaction request to be executed; if the business transaction request is a privacy business transaction request, obtaining a corresponding privacy key, in which the privacy key is an organization privacy key of a privacy organization to which the privacy business transaction request belongs; decrypting and executing the privacy business transaction request according to the privacy key to generate privacy business transaction data, in which the privacy business transaction data comprises at least associated information of privacy content data and the privacy business transaction request; and storing the privacy business transaction data in a blockchain, and storing the privacy content data locally.Type: GrantFiled: July 9, 2020Date of Patent: May 31, 2022Assignee: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.Inventors: Jingqi Cao, Silei Cheng, Lei Zhang, Xiaohe Liu, Haodong Chen, Hui Wang
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Publication number: 20210184835Abstract: Embodiments of the present disclosure provide a privacy transaction processing method, an electronic device and a storage medium, and relates to a field of blockchain technologies. The method includes: obtaining a business transaction request to be executed; if the business transaction request is a privacy business transaction request, obtaining a corresponding privacy key, in which the privacy key is an organization privacy key of a privacy organization to which the privacy business transaction request belongs; decrypting and executing the privacy business transaction request according to the privacy key to generate privacy business transaction data, in which the privacy business transaction data comprises at least associated information of privacy content data and the privacy business transaction request; and storing the privacy business transaction data in a blockchain, and storing the privacy content data locally.Type: ApplicationFiled: July 9, 2020Publication date: June 17, 2021Inventors: Jingqi CAO, Silei CHENG, Lei ZHANG, Xiaohe LIU, Haodong CHEN, Hui WANG
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Publication number: 20210088523Abstract: Disclosed herein are methods of detecting circulating tumor cells by detecting one or more of pan-cytokeratin, epidermal growth factor receptor, human epidermal growth factor receptor 2, mucin 1, plastin 3, circulating cancer associated fibroblast and programmed death-ligand using fiber-optic array scanning technology and automated digital microscopy. The methods disclosed herein can also be used for cancer diagnosis, prognosis, and in the design of cancer treatments.Type: ApplicationFiled: April 2, 2020Publication date: March 25, 2021Inventors: Xiaohe Liu, Lidia C. Sambucetti, Peter B. Madrid, Zheng Ao
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Patent number: 10620112Abstract: Devices, systems and methods detect latent HIV in a patient on anti-retroviral therapy (ART), the method comprising using optical scanning to identify in a cell sample of the patient Gag+ CD4 downregulated cells as in indication of latent HIV.Type: GrantFiled: July 19, 2017Date of Patent: April 14, 2020Assignees: SRI INTERNATIONAL, THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIAInventors: Lidia Sambucetti, Xiaohe Liu, Una O'Doherty
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Publication number: 20190056398Abstract: Embodiments in accordance with the present disclosure include apparatuses, devices, and methods. For example, a method is directed to method exposing immobilized white blood cells from a blood sample to an antigen. And, scanning the immobilized white blood cells and, therefrom, identify and isolate white blood cells from among the immobilized white blood cells that produce an antibody in response to the exposure to the antigen.Type: ApplicationFiled: February 24, 2017Publication date: February 21, 2019Inventors: Feng Wang-Johanning, Gary L. Johanning, Nathan Collins, Xiaohe Liu, Zheng Ao, Lidia Sambucetti
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Publication number: 20170322141Abstract: Devices, systems and methods detect latent HIV in a patient on anti-retroviral therapy (ART), the method comprising using optical scanning to identify in a cell sample of the patient Gag+CD4 downregulated cells as in indication of latent HIV.Type: ApplicationFiled: July 19, 2017Publication date: November 9, 2017Applicants: SRI INTERNATIONAL, THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIAInventors: Lidia Sambucetti, Xiaohe Liu, Una O'Doherty
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Publication number: 20160257986Abstract: Antibiotic susceptibility profile and the bacterial species identification are reported and determined in a single diagnostic test. The method simultaneously reports for a sample of bacteria the identities of the bacteria and their respective antibiotic susceptibilities, the method comprising step(s): contacting the bacteria with antibiotics, a phenotypic fluorescent sensor of antibiotic susceptibility and species- or strain-specific affinity probes, wherein the probes and sensor simultaneously report, respectively, the identities of the bacteria and their respective antibiotic susceptibilities.Type: ApplicationFiled: May 12, 2016Publication date: September 8, 2016Applicant: SRI INTERNATIONALInventors: Peter B. Madrid, Xiaohe Liu
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Patent number: 7591346Abstract: A sound absorptive multilayer composite having an air-impermeable barrier, an air-permeable reinforcing core having an airflow resistance of at least about 100 mks Rayls and a thickness at least about ? the final composite thickness, an air-permeable open cell foam or fibrous pad having an airflow resistance less than about 2000 mks Rayls and a thickness at least about 1/10 the final composite thickness and a semipermeable airflow-resistive membrane having an airflow resistance of about 500 to about 4000 mks Rayls can provide improved acoustic performance. For example, existing vehicular headliner designs may be improved by adding a properly chosen and properly positioned semipermeable airflow-resistive membrane, a properly chosen and properly positioned air-impermeable barrier, or a properly chosen and properly positioned open cell foam layer.Type: GrantFiled: December 4, 2007Date of Patent: September 22, 2009Assignee: 3M Innovative Properties CompanyInventors: Delton R. Thompson, Jr., Xiaohe Liu
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Publication number: 20080073146Abstract: A sound absorptive multilayer composite having an air-impermeable barrier, an air-permeable reinforcing core having an airflow resistance of at least about 100 mks Rayls and a thickness at least about ? the final composite thickness, an air-permeable open cell foam or fibrous pad having an airflow resistance less than about 2000 mks Rayls and a thickness at least about 1/10 the final composite thickness and a semipermeable airflow-resistive membrane having an airflow resistance of about 500 to about 4000 mks Rayls can provide improved acoustic performance. For example, existing vehicular headliner designs may be improved by adding a properly chosen and properly positioned semipermeable airflow-resistive membrane, a properly chosen and properly positioned air-impermeable barrier, or a properly chosen and properly positioned open cell foam layer.Type: ApplicationFiled: December 4, 2007Publication date: March 27, 2008Inventors: Delton Thompson, Xiaohe Liu
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Patent number: 7320739Abstract: A sound absorptive multilayer composite having an air-impermeable barrier, an air-permeable reinforcing core having an airflow resistance of at least about 100 mks Rayls and a thickness at least about ? the final composite thickness, an air-permeable open cell foam or fibrous pad having an airflow resistance less than about 2000 mks Rayls and a thickness at least about 1/10 the final composite thickness and a semipermeable airflow-resistive membrane having an airflow resistance of about 500 to about 4000 mks Rayls can provide improved acoustic performance. For example, existing vehicular headliner designs may be improved by adding a properly chosen and properly positioned semipermeable airflow-resistive membrane, a properly chosen and properly positioned air-impermeable barrier, or a properly chosen and properly positioned open cell foam layer.Type: GrantFiled: July 1, 2004Date of Patent: January 22, 2008Assignee: 3M Innovative Properties CompanyInventors: Delton R. Thompson, Jr., Xiaohe Liu
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Publication number: 20040231914Abstract: A sound absorptive multilayer composite having an air-impermeable barrier, an air-permeable reinforcing core having an airflow resistance of at least about 100 mks Rayls and a thickness at least about ⅔ the final composite thickness, and a semipermeable airflow-resistive decorative membrane having an airflow resistance of about 500 to about 4000 mks Rayls can provide improved acoustic performance while maintaining a low thickness.Type: ApplicationFiled: July 1, 2004Publication date: November 25, 2004Applicant: 3M Innovative Properties CompanyInventors: Delton R. Thompson, Xiaohe Liu
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Publication number: 20040231915Abstract: A sound absorptive multilayer composite having an air-impermeable barrier, an air-permeable reinforcing core having an airflow resistance of at least about 100 mks Rayls and a thickness at least about ⅓ the final composite thickness, an air-permeable open cell foam or fibrous pad having an airflow resistance less than about 2000 mks Rayls and a thickness at least about {fraction (1/10)} the final composite thickness and a semipermeable airflow-resistive membrane having an airflow resistance of about 500 to about 4000 mks Rayls can provide improved acoustic performance. For example, existing vehicular headliner designs may be improved by adding a properly chosen and properly positioned semipermeable airflow-resistive membrane, a properly chosen and properly positioned air- impermeable barrier, or a properly chosen and properly positioned open cell foam layer.Type: ApplicationFiled: July 1, 2004Publication date: November 25, 2004Applicant: 3M Innovative Properties CompanyInventors: Delton R. Thompson, Xiaohe Liu