Patents by Inventor Xiaohong Zhu
Xiaohong Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11981630Abstract: Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I: Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.Type: GrantFiled: January 31, 2023Date of Patent: May 14, 2024Assignee: HANGZHOU NORMAL UNIVERSITYInventors: Mingfeng Xu, Xiaohong Deng, Jinfeng Liang, Yidi Chen, Jing Ren, Qin Zhu
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Publication number: 20240150273Abstract: Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I: Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.Type: ApplicationFiled: January 31, 2023Publication date: May 9, 2024Inventors: Mingfeng XU, Xiaohong DENG, Jinfeng LIANG, Yidi CHEN, Jing REN, Qin ZHU
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Patent number: 11973337Abstract: This invention relates to the technical field of harmonic elimination for ferromagnetic resonance for a voltage transformer (abbreviated as PT), in particular, to a harmonic elimination method for ferromagnetic resonance for an active resistance-matching voltage transformer based on PID-adjustment, including compiling a resistance matching algorithm; designing and building a harmonic elimination control system based on the PID control strategy; presetting an active resistance-matching strategy; designing an engineering scheme for placing resistors.Type: GrantFiled: August 17, 2023Date of Patent: April 30, 2024Assignee: Qujing Power Supply Bureau of Yunnan Power Grid Co., LtdInventors: Xiaohong Zhu, Lianjing Yang, Fei Mao, Rong Zhang, Yang Yang, Jiangyun Su, Wenfei Feng, Zhe Li, Pengjin Qiu, Jianbin Li, Zhikun Hong, Weirong Yang, Changjiu Zhou, Yingqiong Zhang, Rui Xu, Guibing Duan
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Patent number: 11919906Abstract: Crystalline forms of ACP-196, preparation methods, pharmaceutical compositions and uses thereof in the preparation of drugs for treatment and/or prevention of Bruton's tyrosine kinase (BTK)-mediated disorders such as autoimmune diseases or disorders, heteroimmune diseases or disorders, cancers including lymphoma and inflammatory diseases or disorders. As compared with the known solid form of ACP-196, the crystalline forms of the present invention have advantages in crystallinity.Type: GrantFiled: December 23, 2020Date of Patent: March 5, 2024Assignee: Hangzhou SoliPharma Co., Ltd.Inventors: Xiaohong Sheng, Xiaoxia Sheng, Tao Zhu
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Publication number: 20240069426Abstract: A projection curtain is provided in the present invention. The projection curtain at least comprises a reflective layer and one of a colored layer, a diffusion layer, and a Fresnel lens layer. The Fresnel lens layer is a spherical Fresnel lens layer or an aspherical Fresnel lens layer. The Fresnel lens layer comprises a plurality of annular protrusions protruding from a plane, the plurality of annular protrusions are arranged in circular bands. A cross-sectional shape of each annular protrusion along a cross section perpendicular to the plane is a triangular shape or a multi-step shape or a free surface shape. The width of one side of each cross-sectional shape parallel to the plane gradually changes, and gradual change of the cross-sectional shape and the width thereof determines light gathering characteristics of the spherical Fresnel lens layer or the aspherical Fresnel lens layer. A surface of each annular protrusion has scattered microstructures.Type: ApplicationFiled: January 18, 2022Publication date: February 29, 2024Applicants: IVTECH JIANGSU CO., LTD., IVTOUCH CO., LTD., SVG TECH GROUP CO., LTD.Inventors: Xiaohong ZHOU, Ming ZHU, Donglin PU, Pengfei ZHU, Haoshu ZHU, Rubin SUN, Linsen Chen
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Publication number: 20240072531Abstract: This invention relates to the technical field of harmonic elimination for ferromagnetic resonance for a voltage transformer (abbreviated as PT), in particular, to a harmonic elimination method for ferromagnetic resonance for an active resistance-matching voltage transformer based on PID-adjustment, including compiling a resistance matching algorithm; designing and building a harmonic elimination control system based on the PID control strategy; presetting an active resistance-matching strategy; designing an engineering scheme for placing resistors.Type: ApplicationFiled: August 17, 2023Publication date: February 29, 2024Inventors: Xiaohong ZHU, Lianjing YANG, Fei MAO, Rong ZHANG, Yang YANG, Jiangyun SU, Wenfei FENG, Zhe LI, Pengjin QIU, Jianbin LI, Zhikun HONG, Weirong YANG, Changjiu ZHOU, Yingqiong ZHANG, Rui XU, Guibing DUAN
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Patent number: 11824348Abstract: The present disclosure relates to the technical field of potential transformer (PT) ferromagnetic resonance elimination, in particular to a PT ferromagnetic resonance elimination method implemented by actively inputting resistance through an electronic load, including the following steps: setting up a PT, and determining a mapping relationship; constructing a resonance elimination control system; and designing the electronic load as an active resonance elimination device. The present disclosure overcomes a contradiction between a magnitude of resonance elimination resistance and winding overload in a PT open delta during single-phase-to-earth fault and fault clearance, and effectively avoids the technical problems of difficult distinguishing between single-phase-to-earth fault characteristics and power frequency resonance characteristics and causing resonance in a single-phase-to-earth fault process.Type: GrantFiled: May 25, 2023Date of Patent: November 21, 2023Assignee: QUJING POWER SUPPLY BUREAU OF YUNNAN POWER GRID CO., LTDInventors: Xiaohong Zhu, Yin Yang, Sirao Lu, Yuan Shan, Juntao Zeng, Weirong Yang, Zhe Li, Yu Gong, Wenfei Feng, Shoudong Xu, Yongsheng Ning, Rong Zhang, Qibin Mei, Lianjing Yang, Dekai Chen
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Publication number: 20230322785Abstract: The present invention provides compounds of the structural Formula (I) and pharmaceutically acceptable salts thereof, wherein, are as defined herein, pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other therapeutically active agents), and methods for their preparation and use, alone and in combination with other therapeutic agents, as antagonists of A2a and/or A2b receptors, and in the treatment of a variety of diseases, conditions, or disorders that are mediated, at least in part, by the adenosine A2a receptor and/or the adenosine A2b receptor.Type: ApplicationFiled: July 21, 2022Publication date: October 12, 2023Applicant: Merck Sharp & Dohme LLCInventors: Amjad Ali, Christopher W. Boyce, Jared N. Cumming, Duane DeMong, Thomas H. Graham, Subrahmanyam Gudipati, Andrew J. Hoover, Xianhai Huang, Rongze Kuang, Jae-Hun Kim, Joseph M. Kelly, Yeon-Hee Lim, Michael Man-Chu Lo, Jesus Moreno, Jing Su, Heping Wu, Dong Xiao, Younong Yu, Xiaohong Zhu
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Publication number: 20230183275Abstract: The present invention provides a system for continuously producing diethyl methylphosphonite, comprising a rapid mixing reactor and a material circulation subsystem. An inlet of the rapid mixing reactor is provided with a rapid mixing component; the rapid mixing component comprises a first liquid inlet and a second liquid inlet: the second liquid inlet is used for feeding a material containing methylphosphonous dichloride; the material circulation subsystem comprises a filter, a material distribution unit, an acid binding agent premixer and a heat exchanger, which are connected in sequence; the filter is also provided with a solid waste outlet; the material distribution unit is also provided with a diethyl methylphosphonite outlet; the acid binding agent premixer is also provided with a reaction raw material inlet and an acid binding agent inlet; an inlet of the filter is connected to an outlet of the rapid mixing reactor; and an outlet of the heat exchanger is connected to the first liquid inlet.Type: ApplicationFiled: November 18, 2020Publication date: June 15, 2023Applicants: ZHEJIANG WYNCA CHEMICAL INDUSTRY GROUP CO., LTD, TSINGHUA UNIVERSITYInventors: Tiefeng WANG, Shuguang ZHOU, Xiaocheng LAN, Long QIN, Banghao LI, Shenluan YU, Huahai ZHANG, Shengbao JIANG, Minhai TU, Xiaohong ZHU
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Patent number: 11528844Abstract: An automatic harvesting and collecting device for sisal hemp leaves includes an up-and-down moving assembly, a steering device, a braking mechanism, a mechanical vision sensor device, a vehicle traveling and controlling device, a forward-and-backward moving assembly, an omnidirectional automatic positioning and rotating device, a shearing and clamping device, a collecting device and a frame.Type: GrantFiled: November 21, 2020Date of Patent: December 20, 2022Assignee: JIANGXI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Qingkang Liu, Xiaohong Zhu, Sheng Gao, Yao Zhang, Min Chen, Cijun Shuai
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Publication number: 20210153437Abstract: The present invention relates to the technical field of crop harvesting machinery, in particular to an automatic harvesting and collecting device for sisal hemp leaves, which includes an up-and-down moving assembly, a steering device, a braking mechanism, a mechanical vision sensor device, a vehicle traveling and controlling device, a forward-and-backward moving assembly, an omnidirectional automatic positioning and rotating device, a shearing and clamping device, a collecting device and a frame.Type: ApplicationFiled: November 21, 2020Publication date: May 27, 2021Inventors: Qingkang LIU, Xiaohong ZHU, Sheng GAO, Yao ZHANG, Min CHEN, Cijun SHUAI
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Patent number: 10138212Abstract: The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.Type: GrantFiled: February 1, 2016Date of Patent: November 27, 2018Assignee: Merck Sharp & Dohme Corp.Inventors: Amjad Ali, Rongze Kuang, Yeon-Hee Lim, Michael Man-Chu Lo, Pauline C. Ting, Purakkattle Biju, Manuel de Lera Ruiz, Sylvia J. Degrado, Alexander L. Tung, Timothy J. Henderson, Liwu Hong, Jae-Hun Kim, Dong Won-Shik Kim, Joe Lee, Jie Wu, Heping Wu, Yushi Xiao, Tao Yu, Gang Zhou, Xiaohong Zhu, Kevin D. McCormick, Jayaram R. Tagat, Dong Xiao, Tanweer Khan, Jianhua Cao, Michael Berlin, Yonglian Zhang
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Publication number: 20180037554Abstract: The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.Type: ApplicationFiled: February 1, 2016Publication date: February 8, 2018Applicant: Merck Sharp & Dohme Corp.Inventors: Amjad Ali, Rongze Kuang, Yeon-Hee Lim, Michael Man-Chu Lo, Pauline C. Ting, Purakkattle Biju, Manuel de Lera Ruiz, Sylvia J. Degrado, Alexander L. Tung, Timothy J. Henderson, Liwu Hong, Jae-Hun Kim, Dong Won-Shik Kim, Joe Lee, Jie Wu, Heping Wu, Yushi Xiao, Tao Yu, Gang Zhou, Xiaohong Zhu, Kevin D. McCormick, Jayaram R. Tagat, Dong Xiao, Tanweer Khan, Jianhua Cao, Michael Berlin, Yonglian Zhang
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Patent number: 9406439Abstract: The invention relates to a process for forming a lead-based ceramic oxide dielectric material comprising at least one pyrochlore crystalline phase, which process comprises the following steps: a) a step of depositing at least one amorphous layer of said lead-based ceramic oxide material on a substrate; and b) a crystallization annealing step carried out on said amorphous layer at a temperature not exceeding 550° C., by means of which a lead-based ceramic oxide dielectric material comprising at least one pyrochlore phase is obtained. Application to the fabrication of capacitors on integrated circuits.Type: GrantFiled: September 22, 2009Date of Patent: August 2, 2016Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUEInventors: Xiaohong Zhu, Emmanuel Defay, Eric Fribourg-Blanc
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Patent number: 8836535Abstract: A mobile network terminal device and method for monitoring the electrophysiological data and a pathological image are provided, including: a baseband processor module, an electrophysiological data collection module, a keyboard module, a graphics and image display module, an image and picture sensor, a voice communication module, an external data memory card, an external data memory, a Bluetooth module, a USB interface module, a GPS receiver module, an application module set and run in the operation system of the baseband processor; an electrophysiological data remote mobile monitoring, a heart pacemaker remote mobile monitoring, a remote consultation appointment, a pathological image remote mobile monitoring, a data exchange, a medical advisory VoIP communication and a network emergency call being performed by the mobile network terminal device under the control of the application module.Type: GrantFiled: April 21, 2009Date of Patent: September 16, 2014Inventors: Jinjing Zhang, Yonggang Zhao, Haiqing Gao, Yujie Zhou, Shaowen Liu, Xiaohong Zhu
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Patent number: 8673900Abstract: In many embodiments, the present invention provides novel heterocyclic compounds which are modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more disease associated with the central nervous system using such compounds or pharmaceutical compositions.Type: GrantFiled: November 12, 2009Date of Patent: March 18, 2014Assignee: Merck Sharp & Dohme Corp.Inventors: Zhaoning Zhu, William J. Greenlee, Xianhai Huang, Jun Qin, Xiaoxiang Liu, Hongmei Li, Wei Zhou, Anandan Palani, Xiaohong Zhu, Monica L. Vicarel, Mihirbaran Mandal, Zhong-Yue Sun, Chad E. Bennett, Troy Michael McCracken, Gioconda V. Gallo
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Patent number: 8580956Abstract: In its many embodiments, the present invention provides a novel class of heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.Type: GrantFiled: May 28, 2008Date of Patent: November 12, 2013Assignee: Merck Sharp & Dohme Corp.Inventors: Zhaoning Zhu, William J. Greenlee, Zhong-Yue Sun, Gioconda Gallo, Ruo Xu, Xianhai Huang, Xiaohong Zhu
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Patent number: 8518975Abstract: This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).Type: GrantFiled: September 4, 2008Date of Patent: August 27, 2013Assignee: Merck Sharp + Dohme Corp.Inventors: Robert G. Aslanian, Xianhai Huang, Anandan Palani, Jun Qin, Wei Zhou, Xiaohong Zhu, Robert D. Mazzola, Jr., Pawan Dhondi, William J. Greenlee
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Patent number: 8450343Abstract: This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I) wherein R2 is a fused bicyclic ring of the formula (II). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I).Type: GrantFiled: December 4, 2008Date of Patent: May 28, 2013Inventors: Xianhai Huang, Anandan Palani, Jun Qin, Robert G. Aslanian, Zhaoning Zhu, William Greenlee, Hubert Josien, Wei Zhou, Xiaohong Zhu, Chad E. Bennett, Dmitri Pissarnitski, Mihirbaran Mandal, Pawan Dhondi, Troy McCracken, Thomas Bara, Zhiqiang Zhao, Duane Burnett, John Clader
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Patent number: 8357682Abstract: The present invention provides a novel class of heterocyclic compounds of Formula (I) as modulators of gamma secretase, wherein the definitions of the variables of Formula (I) are defined herein, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.Type: GrantFiled: May 5, 2008Date of Patent: January 22, 2013Inventors: Zhaoning Zhu, William J. Greenlee, Zhong-Yue Sun, Gioconda Gallo, Theodros Asberom, Xianhai Huang, Xiaohong Zhu, Mark D. McBriar, Dmitri A. Pissarnitski, Zhiqiang Zhao, Ruo Xu, Hongmei Li, Anandan Palani, Johannes H. Voigt, Robert D. Mazzola, Jr., John Clader, Hubert Josien, Jun Qin