Abstract: A process for treating aged oil by electron beam irradiation is disclosed, comprising the following steps: step 1, homogenizing the aged oil and then feeding the aged oil into a distributor; step 2, forming a liquid layer having a certain thickness on the distributor; step 3, installing and debugging an electron beam irradiation device on the distributor; step 4, installing and debugging a phased-array microwave emitter on the distributor after installing and debugging the electron beam irradiation device; step 5, turning on the electron beam irradiation device and the phased-array microwave emitter; and step 6, dividing the treated aged oil and then allowing the aged oil after dividing to enter an oil pool and a water pool for standing. Oil flows out from an upper layer of the oil pool, a lower layer of the oil pool flows back to an aged oil storage pool.

Abstract: The present invention relates to a single-domain antibody against MSLN (mesothelin) and a preparation method therefor and an application thereof. The MSLN antibody has high affinity for MSLN, and therefore can be applied to the preparation of a medicament for treating tumors, etc.

Abstract: An antibody or antigen-binding fragment specifically binding to HER2, a multi-specific antigen binding molecule, a chimeric antigen receptor, an immune effector cell, a nucleic acid fragment, a vector, a host cell, a pharmaceutical composition, a kit, a preparation method, and an application thereof in treatment of tumors or cancers and detection of HER2, which is of great significance for the development of HER2 antibody therapeutic drugs and detection reagents.

Abstract: Provided are an SGLT-2 inhibitor-sarcosine cocrystal, a preparation method therefor and use thereof. Using sarcosine as a ligand, said cocrystal has higher safety and lower costs; a drug cocrystal has higher stability, and during the production process or storage process of a formulation composition, the crystal form is not easily changed; said cocrystal does not melt when heated, does not stick, aggregate or generate static electricity, and has better mixing uniformity. Said cocrystal has uniform distribution in a prepared pharmaceutical composition, causing that the pharmaceutical composition has better in-vivo release, absorption and efficacy, and has small difference between batches; and the pharmaceutical composition has high stability, and is more conducive to storage and transportation.

Abstract: The present invention relates to the field of medicine, in particular to a composition and use of an SGLT-2 inhibitor and angiotensin receptor blockers, and specifically to a fixed-dose compound composition and use of a sodium-glucose cotransporter 2 (SGLT-2) inhibitor and angiotensin receptor blockers (ARBs). The fixed-dose compound composition is used for the treatment of patients with diabetes and hypertension, and also benefits patients with chronic kidney diseases, preventing or delaying the deterioration of renal failure in patients with chronic kidney diseases (CKD), and preventing cardiovascular (CV) death or death from kidney diseases. In addition, the fixed-dose compound composition has good synergy and good stability, is convenient to carry or administer, significantly reduces the cost of medication, also avoids the risk of excessive and missing administration, and improves the compliance of patients with medication.

Abstract: A method and system for configuring regenerative braking energy recovery devices in urban rail transit provided by the present application, successively including the following steps: calculating a preliminarily configured capacity Pn of a regenerative braking energy recovery device predetermined for the traction substation n, then obtaining an optimally configured capacity Qn of the regenerative braking energy recovery devices; further, configuring the total number of the regenerative braking energy recovery devices; finally, configuring the type of the regenerative braking energy recovery devices. By reasonably configure the capacity and number of regenerative braking energy recovery devices in traction substations, the configuring method of the present application allows the regenerative braking energy generated by a train during braking to be completely absorbed, thus reduce the energy consumption of braking resistors.

Abstract: A method and system for configuring regenerative braking energy recovery devices in urban rail transit provided by the present application, successively including the following steps: calculating a preliminarily configured capacity Pn of a regenerative braking energy recovery device predetermined for the traction substation n, then obtaining an optimally configured capacity Qn of the regenerative braking energy recovery devices; further, configuring the total number of the regenerative braking energy recovery devices; finally, configuring the type of the regenerative braking energy recovery devices. By reasonably configure the capacity and number of regenerative braking energy recovery devices in traction substations, the configuring method of the present application allows the regenerative braking energy generated by a train during braking to be completely absorbed, thus reduce the energy consumption of braking resistors.

Abstract: A free-space optical hybrid is provided. The free-space optical hybrid includes a polarizing beam splitter that split the light beams S and L into horizontal polarization light beams Sx, Lx and orthogonal polarization light beams Sy, Ly, respectively, at least one birefringent crystal splits the horizontal polarization light beams Sx, Lx and orthogonal polarization light beams Sy, Ly into light beams Sxo, Sxe, Lxo, Lxe, Syo, Sye, Lyo, Lye, a light combiner that combine the light beams Sxo+Lxo, Sxo?Lxo, Sxe+jLxe, Sxe?jLxe, Syo+Lyo, Syo?Lyo, Sye+jLye, Sye?jLye and output the light beams at ports. The present invention can realize an optical hybrid in free-space by using a birefringent crystal and can split light beams of different polarization statuses in free-space well. The optical hybrid offers a compact structure and good stability.

Abstract: The present patent application provides a demodulator using MEMS chip for adjusting the phase, which comprises a first interferometer. The difference of the first optical path and the second optical path is an integer multiple of the light speed. A MEMS chip is arranged in at least one optical path of the first interferometer, the MEMS chip is used to adjust the phase of the interference light. The present patent application using MEMS chip for adjusting the phase and phase difference, and also monitor the location of the output beam waveform of the first interferometer and the second interferometer to guide the MEMS chip adjusting the phase difference of the two optical paths. Therefore the adjusting of the phase is more precise by using MEMS chip.

Abstract: A free-space optical hybrid is provided. The free-space optical hybrid includes a polarizing beam splitter that split the light beams S and L into horizontal polarization light beams Sx, Lx and orthogonal polarization light beams Sy, Ly, respectively, at least one birefringent crystal splits the horizontal polarization light beams Sx, Lx and orthogonal polarization light beams Sy, Ly into light beams Sxo, Sxe, Lxo, Lxe, Syo, Sye, Lyo, Lye, a light combiner that combine the light beams Sxo+Lxo, Sxo?Lxo, Sxe+jLxe, Sxe?jLxe, Syo+Lyo, Syo?Lyo, Sye+jLye, Sye?jLye and output the light beams at ports. The present invention can realize an optical hybrid in free-space by using a birefringent crystal and can split light beams of different polarization statuses in free-space well. The optical hybrid offers a compact structure and good stability.