Patents by Inventor Xiaojie Yu

Xiaojie Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10300169
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: May 28, 2019
    Assignee: Allergan, Inc.
    Inventors: Xiaojie Yu, Darin J. Messina, Elizabeta Pavlovic, Cunqi Cui, Kate M. Smither
  • Patent number: 10207725
    Abstract: A method and a device for transmitting signals among compartments of a train are provided. The method comprises: receiving a first signal transmitted via a jumper cable, and extracting first data carried in the first signal; receiving a second signal transmitted wirelessly corresponding to the first signal, and extracting second data carried in the second signal; and determining whether the first data is identical with the second data, and outputting the first signal in a case that it is determined that the first data is identical with the second data, or outputting the second signal in a case that it is determined that the first data is not identical with the second data. The method and the device improve the reliability of transmission of signals among compartments of a train.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: February 19, 2019
    Assignee: CRRC QINGDAO SIFANG CO., LTD.
    Inventors: Miao Wang, Jianying Liang, Huiqing Zhang, Qing Tian, Qingjun Han, Chanjuan Xiao, Mingkun Liu, Baoqiang Shan, Xiaojie Yu
  • Publication number: 20190023222
    Abstract: Disclosed is an alarming and unlocking device. The alarming and unlocking device is installed in a passenger carriage and includes a control switch (10), a communication device, and a locking device, wherein the control switch (10) is provided with an alarming position (11) and an unlocking position (12); the control switch (10) is in signal connection with the communication device; when the control switch (10) is located at the alarming position (11), the communication device is started to receive and send a voice signal; the locking device is installed on a door so as to control the door to lock or unlock; the control switch (10) is in signal connection with the locking device; and when the control switch (10) is located at the unlocking position (12), the locking device performs an unlocking operation. According to the alarming and unlocking device, the problem that a structure for an alarming and unlocking device on a vehicle is relatively complex in the conventional art is solved.
    Type: Application
    Filed: December 5, 2016
    Publication date: January 24, 2019
    Inventors: Bo CHEN, Xiaojie YU, Lijun MA, Qing TIAN, Huiqing ZHANG, Qingjun HAN, Xin JIANG, Jianying LIANG
  • Patent number: 10154951
    Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: December 18, 2018
    Assignee: ALLERGAN, INC.
    Inventors: Elizabeta Pavlovic, Monica A. Serban, Xiaojie Yu, Nicholas J. Manesis
  • Publication number: 20180305453
    Abstract: The present disclosure relates to monovalent antibodies and chimeric proteins (comprising the monovalent antibodies) for the treatment of an auto-immune inflammatory disorder or condition. The monovalent antibody moiety lacks a Fc region, is specific for an activating Fc receptor and is for limiting or avoiding the activation of an immune cell induced in the presence and upon the binding of a ligand of the activating Fc receptor to the activating Fc receptor. The monovalent antibodies and chimeric proteins are especially useful for the prevention, treatment or alleviation of symptoms associated with an auto-immune inflammatory disorder caused or maintained by the engagement of an auto-antibody having a Fc region capable of engaging the activating Fc receptor to mediate the pathological destructions of cells or tissues.
    Type: Application
    Filed: October 20, 2016
    Publication date: October 25, 2018
    Applicant: Canadian Blood Services
    Inventors: Alan H. Lazarus, Xiaojie Yu, William Peter Sheffield
  • Publication number: 20180303742
    Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.
    Type: Application
    Filed: June 29, 2018
    Publication date: October 25, 2018
    Inventors: Elizabeta Pavlovic, Monica A. Serban, Xiaojie Yu, Nicholas J. Manesis
  • Publication number: 20180236215
    Abstract: Microneedle arrays for introducing an active ingredient through a skin surface of a subject can include a base layer, a plurality of microneedles projecting from the base layer, and an active ingredient. Each of the microneedles comprises an elongate body having a proximal portion and a distal portion, in which the proximal portion is attached to the base layer. Each of the microneedles comprises at least one dissolvable polymer. The active ingredient is incorporated in the elongate body, and the active ingredient is present only in the distal portion and at least internally in the distal portion.
    Type: Application
    Filed: February 16, 2018
    Publication date: August 23, 2018
    Inventors: Futian LIU, Xiaojie YU, Lance E. STEWARD, Guang Wei LU, Patrick M. HUGHES, Sheshadri NEERVANNAN
  • Publication number: 20180214601
    Abstract: Provided are injectable, hyaluronic acid-based dermal filler compositions including conjugated vitamin C derivatives. The compositions provide for extended release of active vitamin C into tissue, promoting collagenesis and other benefits to skin.
    Type: Application
    Filed: March 26, 2018
    Publication date: August 2, 2018
    Inventors: Futian Liu, Xiaojie Yu, Jessamine P. Winer-Jones, Nicholas J. Manesis, Hengli Liu, Gabriel Njikang, Athene Wan Chie Chan
  • Publication number: 20180193523
    Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.
    Type: Application
    Filed: March 7, 2018
    Publication date: July 12, 2018
    Inventors: Gabriel N. Njikang, Xiaojie Yu, Futian Liu, Sumit Paliwal, Nicholas J. Manesis
  • Publication number: 20180147307
    Abstract: Method for sterilizing a hydrogel composition include subjecting the composition to pulsed light comprising broadband spectrum radiation, the pulsed light being at a dose effective to sterilize the composition without causing significant change in rheology of the composition.
    Type: Application
    Filed: January 26, 2018
    Publication date: May 31, 2018
    Inventors: Kaustubh S. Chitre, Xiaojie Yu, Nicholas J. Manesis
  • Patent number: 9962464
    Abstract: Provided are injectable, hyaluronic acid-based dermal filler compositions including conjugated vitamin C derivatives. The compositions provide for extended release of active vitamin C into tissue, promoting collagenesis and other benefits to skin.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: May 8, 2018
    Assignee: Allergan, Inc.
    Inventors: Futian Liu, Xiaojie Yu, Jessamine P. Winer-Jones, Nicholas J. Manesis, Hengli Liu, Gabriel Njikang, Athene Wan Chie Chan
  • Patent number: 9950092
    Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: April 24, 2018
    Assignee: Allergan, Inc.
    Inventors: Gabriel N. Njikang, Xiaojie Yu, Futian Liu, Sumit Paliwal, Nicholas J. Manesis
  • Publication number: 20180055971
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Application
    Filed: August 24, 2017
    Publication date: March 1, 2018
    Inventors: Xiaojie YU, Darin J. MESSINA, Elizabeta PAVLOVIC, Cunqi CUI, Kate M. SMITHER
  • Publication number: 20170348463
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Application
    Filed: August 25, 2017
    Publication date: December 7, 2017
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • Patent number: 9821086
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: November 21, 2017
    Assignee: Allergan, Inc.
    Inventors: Xiaojie Yu, Nicholas J. Manesis, Jacob Pollock
  • Patent number: 9795711
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: October 24, 2017
    Assignee: Allergan, Inc.
    Inventors: Xiaojie Yu, Nicholas J. Manesis, Jacob Pollock
  • Patent number: 9782517
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: October 10, 2017
    Assignee: Allergan, Inc.
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • Publication number: 20170266344
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.
    Type: Application
    Filed: May 31, 2017
    Publication date: September 21, 2017
    Inventors: Xiaojie Yu, Nicolas J. Manesis, Jacob Pollock
  • Patent number: 9737633
    Abstract: Provided are injectable, hyaluronic acid-based hydrogel compositions including conjugated vitamins.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: August 22, 2017
    Assignee: Allergan, Inc.
    Inventors: Futian Liu, Xiaojie Yu, Nicholas J. Manesis, Athene Wan Chie Chan
  • Publication number: 20170224873
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Application
    Filed: April 24, 2017
    Publication date: August 10, 2017
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina