Patents by Inventor Xiaokun Li
Xiaokun Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240101600Abstract: The present disclosure discloses a fibroblast growth factor receptor (FGFR)-targeting antagonistic short peptide, namely a short peptide compound P48 with the amino acid sequence of Ser-Pro-Pro-Arg-Tyr-Pro-Gly-Gly-Gly-Ser-NH2, where the short peptide compound P48 inhibits an FGFR pathway to inhibit cell proliferation and migration.Type: ApplicationFiled: December 8, 2020Publication date: March 28, 2024Inventors: Xiaokun Li, Jianzhang Wu, Wulan Li, Lingzi Chen, Lei Fan, Yuepiao Cai
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Publication number: 20240095272Abstract: Provided are a search request processing method, an apparatus, a computer device, a storage medium, a computer product, and a computer program. The method includes: in response to a search instruction, sending a search request comprising a target question; acquiring a plurality of sets of answer information corresponding to the target question, wherein each set of answer information includes answer summary information and a multimedia content supporting the answer summary information; the genre of the multimedia content is determined on the basis of a category of the target question, and the answer summary information is extracted on the basis of the multimedia content; and displaying the answer summary information in each set of answer information on a search result page, and displaying, when any piece of answer summary information is selected, at least part of the multimedia content supporting the selected answer summary information.Type: ApplicationFiled: November 30, 2023Publication date: March 21, 2024Inventors: Yating Lin, Yujie Wu, Mulan Hou, Xiaokun Jiang, Pengshuai Li, Zijian Zhang, Chaoyang Wang
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Patent number: 11858914Abstract: Disclosed are a pyrimidine small-molecule compound and an application thereof. The pyrimidine small-molecule compound has efficient inhibitory activity towards PDGFR? and PDGFR? kinases, but has relatively weak inhibitory activity towards other kinases. Therefore, the compound has very high selectivity and is capable of being used as a potential drug for resisting tumors or relieving ophthalmic diseases such as wet age-related macular degeneration or uveitis.Type: GrantFiled: June 8, 2023Date of Patent: January 2, 2024Assignee: WENZHOU MEDICAL UNIVERSITYInventors: Xiaokun Li, Zhiguo Liu, Li Lin, Xiaohui Zheng, Jianchang Qian
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Publication number: 20230312529Abstract: Disclosed are a pyrimidine small-molecule compound and an application thereof. The pyrimidine small-molecule compound has efficient inhibitory activity towards PDGFR? and PDGFR? kinases, but has relatively weak inhibitory activity towards other kinases. Therefore, the compound has very high selectivity and is capable of being used as a potential drug for resisting tumors or relieving ophthalmic diseases such as wet age-related macular degeneration or uveitis.Type: ApplicationFiled: June 8, 2023Publication date: October 5, 2023Inventors: Xiaokun LI, Zhiguo LIU, Li LIN, Xiaohui ZHENG, Jianchang QIAN
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Publication number: 20230187126Abstract: A high-frequency rotary transformer, a machine and a high frequency transformer are defined that are simpler to manufacture and less expensive than existing transformers and machines. The high-frequency rotary transformer includes: a primary transformer core comprising a plurality of primary core elements, each defining a primary transformer winding portion; a secondary transformer core comprising a plurality of secondary core elements, each defining a secondary transformer winding portion; a primary winding associated with each of the primary core elements; and a secondary winding associated with each of the secondary core elements. The primary transformer core and the secondary transformer core together define a transformer core having a flux pathway linking the primary and secondary windings, and the primary transformer core and the secondary transformer core are configured to rotate relative to each other.Type: ApplicationFiled: May 7, 2021Publication date: June 15, 2023Inventors: Junwei Lu, Xiaokun Li
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Publication number: 20210301660Abstract: The disclosure belongs to the field of tunnel construction technologies, and more particularly, relates to a construction method for making a water-rich sand layer shield over cross an existing line and underneath cross a sewage push pipe at a close range. The method specifically includes the following steps of: S1) before construction, using MIDAS GTS NX software and FLAC3D to optimize a tunneling scheme antecedently by numerical simulation to determine a part of unfavourable stress; S2) tunneling a test section, the test section being a stratum crossing a front shield direction by 45 m to 60 m; and S3) performing shield crossing construction, wherein a shield crossing construction process includes the steps of: 1) controlling a soil pressure; 2) controlling a shield thrust; 3) performing synchronous grouting; 4) performing a ballasting measure in a tunnel; and 5) performing automatic monitoring in the tunnel.Type: ApplicationFiled: January 13, 2021Publication date: September 30, 2021Inventors: Gangzhu LI, Wei LIU, Yapeng LI, Hongbo DU, Bole SUN, Xinlong ZHAO, Haidong WANG, Liang QIN, Xiaohui CHU, Bo LI, Qingkai LIANG, Xingkai SHI, Lei WU, Xiaokun LI, Lihao CUI, Zhaoxu LI, Xianbin DAI, Lanying HE, Shiwei ZHAN, Yu LIU
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Publication number: 20170184593Abstract: This invention publicizes a chronic renal disease diagnostic kit, comprised of FGF23 monoclonal antibody, biotin labeling reagent Sulfo-NHS-LC-Biotin, PBS buffer solution (pH7.0, 0.1M), casein saline solution, streptomycin avidin and substrate TMB. The labeling condition is the weight ratio of FGF23 antibody and Sulfo-NHS-LC-Biotin, which is 1:5-1:12. The dilution ratio of streptomycin avidin is 1:3000. The lowest testing threshold limit value of FGF23 kit is 10 pg/ml, whose sensitivity is 10 times higher than that of common monoclonal antibody, which is very significant for early diagnose of chronic renal disease.Type: ApplicationFiled: December 18, 2015Publication date: June 29, 2017Inventors: Xiaokun Li, Guang Liang, Xiaojie Wang, Shijun Li, Peisheng Hu
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Patent number: 9634540Abstract: A magnetic suspension planar motor comprises a structure of superconductor excitation. A primary base plate is in a shape of board. Armature windings are fixed on an air gap side of the primary base plate. A secondary base plate in a secondary structure is evenly divided into 2 h*2 h magnet cells. 2 h2 superconducting magnets are respectively fixed in the magnet cells on the secondary base plate, which resembles a checkerboard pattern. The superconducting magnets are adjacent to each other, neither in a horizontal direction nor in a vertical direction. The superconducting magnets are magnetized parallelly, and magnetization directions of the superconducting magnets are perpendicular to a surface on an air gap side of the secondary base plate. The superconducting magnets in a same row or column have same magnetization directions, and the superconducting magnets in adjacent rows columns have contrary magnetization directions. A cooling container shields all of the superconducting magnets.Type: GrantFiled: July 3, 2012Date of Patent: April 25, 2017Assignee: HARBIN INSTITUTE OF TECHNOLOGYInventors: Baoquan Kou, Xiaokun Li, Lu Zhang, He Zhang
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Patent number: 9356160Abstract: A flat panel sensor and a flat panel detector are provided on the basis of a top-gate TFT structure. The flat panel sensor comprises a base substrate, and a top-gate TFT and a storage capacitor that are formed on the base substrate; the storage capacitor includes a first conductive layer, a second conductive layer disposed in opposition to the first conductive layer, a third conductive layer for output of an electric signal, and a ground line; the first conductive layer is directly connected to a drain electrode and an active layer of the top-gate TFT, the second conductive layer is directly connected to the ground line, and the third conductive layer is connected to the first conductive layer through a via hole.Type: GrantFiled: July 31, 2013Date of Patent: May 31, 2016Assignee: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventor: Xiaokun Li
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Patent number: 9105525Abstract: The embodiment of the present invention discloses a touch unit, an array substrate, a liquid crystal cell substrate and a touch display device. The touch unit comprise a plurality of touch sub-units, each of which comprising a sensor thin film transistor (TFT), an sensing capacitor, a reading induction line and a memory capacitor, the capacitance of the memory capacitor being less than that of the sensing capacitor. Due to the memory capacitor is added to stabilize the voltage of the sensor TFT, the interference of noise upon the voltage of the sensor TFT is reduced, thus effectively improving the signal stability of the touch unit.Type: GrantFiled: October 30, 2012Date of Patent: August 11, 2015Assignee: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Cheng Li, Xiaokun Li, Dong Chen, Yang Pei
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Publication number: 20150171119Abstract: The embodiment of the present invention discloses a touch unit, an array substrate, a liquid crystal cell substrate and a touch display device. The touch unit comprise a plurality of touch sub-units, each of which comprising a sensor thin film transistor (TFT), an sensing capacitor, a reading induction line and a memory capacitor, the capacitance of the memory capacitor being less than that of the sensing capacitor. Due to the memory capacitor is added to stabilize the voltage of the sensor TFT, the interference of noise upon the voltage of the sensor TFT is reduced, thus effectively improving the signal stability of the touch unit.Type: ApplicationFiled: October 30, 2012Publication date: June 18, 2015Inventors: Cheng Li, Xiaokun Li, Dong Chen, Yang Pei
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Publication number: 20140327327Abstract: A magnetic suspension planar motor comprises a structure of superconductor excitation. A primary base plate is in a shape of board. Armature windings are fixed on an air gap side of the primary base plate. A secondary base plate in a secondary structure is evenly divided into 2 h*2 h magnet cells. 2 h2 superconducting magnets are respectively fixed in the magnet cells on the secondary base plate, which resembles a checkerboard pattern. The superconducting magnets are adjacent to each other, neither in a horizontal direction nor in a vertical direction. The superconducting magnets are magnetized parallelly, and magnetization directions of the superconducting magnets are perpendicular to a surface on an air gap side of the secondary base plate. The superconducting magnets in a same row or column have same magnetization directions, and the superconducting magnets in adjacent rows columns have contrary magnetization directions. A cooling container shields all of the superconducting magnets.Type: ApplicationFiled: July 3, 2012Publication date: November 6, 2014Inventors: Baoquan Kou, Xiaokun Li, Lu Zhang, He Zhang
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Publication number: 20140034950Abstract: A flat panel sensor and a flat panel detector are provided on the basis of a top-gate TFT structure. The flat panel sensor comprises a base substrate, and a top-gate TFT and a storage capacitor that are formed on the base substrate; the storage capacitor includes a first conductive layer, a second conductive layer disposed in opposition to the first conductive layer, a third conductive layer for output of an electric signal, and a ground line; the first conductive layer is directly connected to a drain electrode and an active layer of the top-gate TFT, the second conductive layer is directly connected to the ground line, and the third conductive layer is connected to the first conductive layer through a via hole.Type: ApplicationFiled: July 31, 2013Publication date: February 6, 2014Applicant: Beijing BOE Optoelectronics Technology Co., Ltd.Inventor: Xiaokun Li
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Publication number: 20120133613Abstract: Embodiments of the present disclosure provide a capacitive touch panel capable of simplifying a manufacture process thereof. The capacitive touch panel comprises a first substrate and a second substrate provided opposite to each other, wherein a common electrode and at least two parallel electrode lines are disposed between the first substrate and the second substrate, at least two touch electrodes are connected in series by each of the electrode lines, any two of the touch electrodes connected by a same electrode line have an area different from each other, varying sequentially, the touch electrode and the common electrode form a capacitor, and the electrode line is connected to a touch signal sensing device. The capacitive touch panel provided by embodiments of the present disclosure may achieve one-dimensioned positioning.Type: ApplicationFiled: November 29, 2011Publication date: May 31, 2012Applicant: Beijing BOE Optoelectronics Technology Co., Ltd.Inventors: Xiaochuan CHEN, Wei LI, Xiaokun LI
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Patent number: 7403664Abstract: A method detects traffic events in a compressed video. Feature vectors are extracted from the compressed video. The feature vector are provided to a Gaussian mixture hidden Markov model. Then, a maximum likelihood of the Gaussian mixture hidden Markov model is determined to classify the plurality of feature vector as traffic events.Type: GrantFiled: February 26, 2004Date of Patent: July 22, 2008Assignee: Mitsubishi Electric Research Laboratories, Inc.Inventors: Faith M. Porikli, Xiaokun Li
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Publication number: 20050190975Abstract: A method detects traffic events in a compressed video. Feature vectors are extracted from the compressed video. The feature vector are provided to a Gaussian mixture hidden Markov model. Then, a maximum likelihood of the Gaussian mixture hidden Markov model is determined to classify the plurality of feature vector as traffic events.Type: ApplicationFiled: February 26, 2004Publication date: September 1, 2005Inventors: Fatih Porikli, Xiaokun Li