Abstract: A formulation includes a carrier agent formed by conjugating at least one biologically active hydrophobic compound with at least one hydrophilic compound, the at least one biologically active hydrophobic compound selected from the group of farnesylthiosalicylic acid and a derivative of farnesylthiosalicylic acid which is biologically active as an RAS antagonist, wherein a plurality of the carrier agents are adapted to assemble into a structure and the at least one biologically active hydrophobic compound is conjugated with the at least one hydrophilic compound via a linkage which is labile in vivo, and a biologically active compound associated with the carrier agent.

Abstract: A method of forming or creating a formulation for a compound to be delivered includes creating a carrier agent by conjugating at least one hydrophobic domain or hydrophobic compound with at least one hydrophilic domain or hydrophilic compound and associating the compound to be delivered with the carrier agent to create the formulation. The at least one hydrophobic compound has the formula: wherein R1 is a farnesyl group, a geranyl group or geranyl-geranyl group, X is O, S, SO, SO2, NH or Se, Z is C—R2 or N, R2 is H, CN, CO2R7, SO3R7, CONR7R8 or SO2NR7R8, wherein R7 and R8 are each independently H, an alkyl group, an alkenyl group, CO2M or SO3M, wherein M is a cation and R3, R4, and R5 are independently H, a carboxyl group, an alkyl group, an alkenyl group, an aminoalkyl group, a nitroalkyl group, a nitro group, a halo atom, an amino group, a mono-alkylamino group, a di-alkylamino group, mercapto group, a mercaptoalkyl group, an azido group or a thiocyanato group.

Abstract: An arbitrary customer instance is transferred from a customer environment to a target managed-infrastructure-as-a-service cloud environment as a transferred image. An image adjustment plan, capturing at least one adjustment required to render the transferred image compliant with standards of the target managed-infrastructure-as-a-service cloud environment, is formulated. The image adjustment plan is executed to adjust the transferred image to obtain an adjusted image compliant with standards of the target managed-infrastructure-as-a-service cloud environment. The adjusted image is on-boarded into the managed-infrastructure-as-a-service cloud environment as a standard image thereof.

Abstract: An arbitrary customer instance is transferred from a customer environment to a target managed-infrastructure-as-a-service cloud environment as a transferred image. An image adjustment plan, capturing at least one adjustment required to render the transferred image compliant with standards of the target managed-infrastructure-as-a-service cloud environment, is formulated. The image adjustment plan is executed to adjust the transferred image to obtain an adjusted image compliant with standards of the target managed-infrastructure-as-a-service cloud environment. The adjusted image is on-boarded into the managed-infrastructure-as-a-service cloud environment as a standard image thereof.

Abstract: During a process of migrating a source system into a standardized virtual environment, virtual machine instances of the source system executing in a hypervisor are snapshotted as virtual machine images in an operational repository of the hypervisor. The virtual machine images in the operational repository are short-term snapshots. From time to time during the migration process, long-term snapshots of the source system are created by checking given ones of the virtual machine images from the hypervisor operational repository into an image library as image objects.

Abstract: A conformance checker is received on a system that contains hostable content, and is executed. One or more results provided by the conformance checker are evaluated; and the hostable content is migrated to a destination host in accordance with the evaluating step.

Abstract: A foreign instance is transferred from a customer environment to a target infrastructure-as-a-service cloud environment as an image. The foreign instance is adjusted to standards of the infrastructure-as-a-service cloud environment to obtain an adjusted instance. The adjusted instance is registered into a management system of the infrastructure-as-a-service cloud environment.

Abstract: At least one target virtual disk descriptor that describes at least one virtual disk associated with an existing target virtual machine in a target virtualized environment is merged with at least one source virtual disk descriptor that describes at least one virtual disk associated with a source. The merging is carried out to obtain at least one merged virtual disk descriptor compatible with the target virtualized environment. The at least one virtual disk associated with the existing target virtual machine in the target virtualized environment is replaced with the at least one virtual disk associated with the source, in accordance with the at least one merged virtual disk descriptor.

Abstract: During a process of migrating a source system into a standardized virtual environment, virtual machine instances of the source system executing in a hypervisor are snapshotted as virtual machine images in an operational repository of the hypervisor. The virtual machine images in the operational repository are short-term snapshots. From time to time during the migration process, long-term snapshots of the source system are created by checking given ones of the virtual machine images from the hypervisor operational repository into an image library as image objects.

Abstract: At least one target virtual disk descriptor that describes at least one virtual disk associated with an existing target virtual machine in a target virtualized environment is merged with at least one source virtual disk descriptor that describes at least one virtual disk associated with a source. The merging is carried out to obtain at least one merged virtual disk descriptor compatible with the target virtualized environment. The at least one virtual disk associated with the existing target virtual machine in the target virtualized environment is replaced with the at least one virtual disk associated with the source, in accordance with the at least one merged virtual disk descriptor.

Abstract: A method of checking file system compliance including receiving a plurality of compliance rules corresponding to a file system of a production system, collecting, by a collector, file system meta data from the file system, analyzing, by an analyzer, the file system meta data using the plurality of compliance rules to determine at least one compliance deviation of the file system, and throttling the collector and the analyzer independently of one-another, wherein the collector and the analyzer are configured according to a model of performance for the production system and a schedule for the collection and analyzing.

Abstract: Access is obtained to a plurality of information technology services problem tickets. At least a first subset of the tickets include free text tickets with server names embedded in unstructured text fields. The server names are extracted from the first subset of the tickets via a statistical machine learning technique. Using the extracted server names, those of the first subset of the tickets from which the server names have been extracted are linked to corresponding server entries in a configuration information database to facilitate resolution of problems associated with the first subset of the tickets from which the server names have been extracted; and/or at least one of the extracted server names is identified as missing from a list of known server names.

Abstract: At least one target virtual disk descriptor that describes at least one virtual disk associated with an existing target virtual machine in a target virtualized environment is merged with at least one source virtual disk descriptor that describes at least one virtual disk associated with a source. The merging is carried out to obtain at least one merged virtual disk descriptor compatible with the target virtualized environment. The at least one virtual disk associated with the existing target virtual machine in the target virtualized environment is replaced with the at least one virtual disk associated with the source, in accordance with the at least one merged virtual disk descriptor.

Abstract: In an approach for detecting one or more applications in a VM, one or more processors establish a time duration. One or more processors detect two or more files, each file in the two or more files having a time stamp time that differs from a last modified time stamp time of at least one other file in the two or more files by no more than the time duration. One or more processors record an identifier for each file of the two or more files, a location, a name, and a last modified time stamp time of each file of the two or more files. One or more processors map the two or more files to an application installed on the VM.

Abstract: A composite software stack is distributed as a virtual appliance. A new virtual appliance is published by obtaining a parent virtual appliance; configuring the new virtual appliance; obtaining file level differences between the parent virtual appliance and the new virtual appliance; and publishing the new virtual appliance as a patch comprising the file level differences relative to the parent virtual appliance. The file level differences comprise additions, deletions and/or modifications to the parent virtual appliance. An update to a given virtual appliance can be published as a fix pack, wherein the fix pack comprises file level differences relative to the given virtual appliance. An end user obtains a desired virtual appliance by selecting the desired virtual appliance; obtaining metadata for the desired virtual appliance comprising an identifier of a patch file and a parent virtual appliance; and applying the patch file to the parent virtual appliance to get a modified virtual appliance.

Abstract: During a process of migrating a source system into a standardized virtual environment, virtual machine instances of the source system executing in a hypervisor are snapshotted as virtual machine images in an operational repository of the hypervisor. The virtual machine images in the operational repository are short-term snapshots. From time to time during the migration process, long-term snapshots of the source system are created by checking given ones of the virtual machine images from the hypervisor operational repository into an image library as image objects.

Abstract: A conformance checker is received on a system that contains hostable content, and is executed. One or more results provided by the conformance checker are evaluated; and the hostable content is migrated to a destination host in accordance with the evaluating step.

Abstract: One or more requirements of a target hosting environment are captured in a specification. The specification is automatically checked against a source content of a source environment with a conformance checker, where the source content is to be migrated to the target hosting environment. It is determined whether the source content conforms to the specification.

Abstract: Techniques for composing an application resource model are disclosed.

Abstract: A method of forming or creating a formulation for a compound to be delivered includes creating a carrier agent by conjugating at least one hydrophobic domain or hydrophobic compound with at least one hydrophilic domain or hydrophilic compound and associating the compound to be delivered with the carrier agent to create the formulation. The at least one hydrophobic compound has the formula: wherein R1 is a farnesyl group, a geranyl group or geranyl-geranyl group, X is O, S, SO, SO2, NH or Se, Z is C—R2 or N, R2 is H, CN, CO2R7, SO3R7, CONR7R8 or SO2NR7R8, wherein R7 and R8 are each independently H, an alkyl group, an alkenyl group, CO2M or SO3M, wherein M is a cation and R3, R4, and R5 are independently H, a carboxyl group, an alkyl group, an alkenyl group, an aminoalkyl group, a nitroalkyl group, a nitro group, a halo atom, an amino group, a mono-alkylamino group, a di-alkylamino group, mercapto group, a mercaptoalkyl group, an azido group or a thiocyanato group.