Abstract: A bioartificial liver (BAL) based on human induced pluripotent stem cells (iPSCs)-derived hepatocyte-like cells (HLCs) and a multilayer porous bioreactor is provided. The plasma separation/retransfusion loop part includes a blood input pipe, an exhaust pipe spring clamp, a blood input peristaltic pump, a heparin pump, a plasma separation column, a first pressure monitor, and a heater. The cell reactor/plasma component exchange double-loop part includes a plasma input peristaltic pump, and a semipermeable membrane exchange column, a plasma exchange peristaltic pump, a red blood cell (RBC) pool, a membrane lung, a multilayer porous bioreactor, a second pressure monitor, and a third pressure monitor arranged in a 37° C. dedicated incubator. An outlet of the third pressure monitor and a blood cell outlet are connected to an inlet of the first pressure monitor, and then connected to the heater and a blood output pipe in sequence.

Abstract: A method for additively printing extension segments on workpieces using an additive manufacturing machine includes controlling, with a computing system, an operation of a print head of the machine such that a region of interest of a build plate of the machine is scanned with an electromagnetic radiation beam. Additionally, the method includes receiving, with the computing system, data associated with reflections of the beam off of the build plate as the region interest is scanned. Furthermore, the method includes receiving, with the computing system, data associated with a location of the beam relative to the build plate. Moreover, the method includes determining, with the computing system, a location of a workpiece interface based on the received data. In addition, the method includes controlling, with the computing system, the operation of the print head such that an extension segment is additively printed on the determined workpiece interface.

Abstract: A bioartificial liver (BAL) based on human induced pluripotent stem cells (iPSCs)-derived hepatocyte-like cells (HLCs) and a multilayer porous bioreactor is provided. The plasma separation/retransfusion loop part includes a blood input pipe, an exhaust pipe spring clamp, a blood input peristaltic pump, a heparin pump, a plasma separation column, a first pressure monitor, and a heater. The cell reactor/plasma component exchange double-loop part includes a plasma input peristaltic pump, and a semipermeable membrane exchange column, a plasma exchange peristaltic pump, a red blood cell (RBC) pool, a membrane lung, a multilayer porous bioreactor, a second pressure monitor, and a third pressure monitor arranged in a 37° C. dedicated incubator. An outlet of the third pressure monitor and a blood cell outlet are connected to an inlet of the first pressure monitor, and then connected to the heater and a blood output pipe in sequence.

Abstract: An isolated power converter and a hydrogen production system are provided. An electrical connection structure in the isolated power converter includes N secondary winding output bus bars, N rectifier circuit input bus bars, and a positive-negative bus bar, where N is greater than or equal to 1. A secondary winding may include M tapping points, and the secondary winding output bus bar and the rectifier circuit input bus bar that correspond to the secondary winding each include M copper bars that are insulated and stacked. The M tapping points of the secondary winding overlap the M copper bars of the secondary winding output bus bar at input ends of the M copper bars, respectively. The positive-negative bus bar includes two copper bars that are insulated and stacked.

Abstract: The present disclosure relates to support structures for three dimensional (3D) printing, methods of preparing the support structures, and methods of using the support structures. In particular, the support structures comprise a hydrogel comprised of a cellulose derivative. Preferably, the support structures are biodegradable and easily removed without generating toxic waste.

Abstract: A case heat dissipation structure is provided, which includes a case, a heat exchange assembly and a fan assembly. The case has a first heat dissipation chamber and a second heat dissipation chamber that are communicated with each other, and multiple heat sources are mounted in the first heat dissipation chamber and the second heat dissipation chamber, a liquid inlet for cooling liquid to flow in and a liquid outlet for cooling liquid to flow out are provided on the case. The heat exchange assembly is mounted in the first heat dissipation chamber, the heat exchange assembly comprises a heat exchanger, which is arranged between the liquid inlet and the liquid outlet. The fan assembly is mounted in the first heat dissipation chamber or the second heat dissipation chamber, and is used for driving the air in the first heat dissipation chamber and the second heat dissipation chamber to circulate mutually in operation.

Abstract: An additive manufacturing system includes a build platform and at least two laser heads. Each laser head includes at least one laser device, an optical sensor, and a computing device. The build platform includes a plurality of calibration marks. The laser device is configured to generate a laser beam. The laser beam is directed toward the plurality of calibration marks and the build platform. The optical sensor is configured to detect a scattering signal of the laser beam generated by reflecting off of the plurality of calibration marks and the build platform. The computing device is configured to receive the scattering signal from the optical sensor. The computing device is configured to align the laser heads such that the scattering signal aligns with the plurality of calibration marks and such that the laser heads align with each other.

Abstract: Determining a quality score for a part manufactured by an additive manufacturing machine based on build parameters and sensor data without the need for extensive physical testing of the part. Sensor data is received from the additive manufacturing machine during manufacture of the part using a first set of build parameters. The first set of build parameters is received. A first algorithm is applied to the first set of build parameters and the received sensor data to generate a quality score. The first algorithm is trained by receiving a reference derived from physical measurements performed on at least one reference part built using a reference set of build parameters. The quality score is output via the communication interface of the device.

Abstract: The present invention provides a biomarker PCDH9 for molecular classification of prostate cancer and for evaluation of prostate cancer prognosis and uses thereof. The biomarker PCDH9 can be DNA or mRNA of PCDH9 or a protein encoded thereby. The present invention also provides a prostate cancer in vitro diagnostic product comprising a detection reagent of the biomarker PCDH9.

Abstract: The present approach generally relates to systems and methods for implementing energy modulated tomographic imaging of nanoparticles. In certain embodiments, a first energy is used to activate probe particles labeling an anatomy or tissue of interest. The probe particles, once activated, emit photons at a different rate and/or spectrum in response to an underlying physiological event, such as action potentials propagating in the labeled anatomy or tissue. The emitted photons may then be detected and used to map or image the occurrence of the physiological event.

Abstract: The present invention provides an application of PLXNA1 as a biomarker for predicting the occurrence, development, and prognosis of prostate cancer and for distinguishing prostate cancer being progressive and with high malignancy. By detecting a change in a PLXNA1 DNA copy number, and expression levels of mRNA and a protein encoded thereby, a diagnosis and prognosis of prostate cancer are performed. The present invention also provides an application of PLXNA1 as a therapeutic target for prostate cancer. The present invention also provides a kit for diagnosing and predicting prostate cancer.

Abstract: An electronical connector includes an insulation body and first and second conductive terminals. The insulation body includes a basal part, a middle part and a front end part defining a socketing space. The insulation body defines first and second terminal slots, with both communicating with the socketing space. The first terminal slot is positioned in the middle part and on an inner surface of a lower wall of the front end part. The second terminal slot is positioned in the middle part and on an inner surface of an upper wall of the front end part. The first and second conductive terminals are individually positioned in the first and second terminal slots. The first and second conductive terminals each include a contact part, a connection part, and a welding part. The contact part is positioned in the socketing space and the welding part protrudes out of the basal part.

Abstract: An electronical connector includes an insulation body and first and second conductive terminals. The insulation body includes a basal part, a middle part and a front end part defining a socketing space. The insulation body defines first and second terminal slots, with both communicating with the socketing space. The first terminal slot is positioned in the middle part and on an inner surface of a lower wall of the front end part. The second terminal slot is positioned in the middle part and on an inner surface of an upper wall of the front end part. The first and second conductive terminals are individually positioned in the first and second terminal slots. The first and second conductive terminals each include a contact part, a connection part, and a welding part. The contact part is positioned in the socketing space and the welding part protrudes out of the basal part.

Abstract: Systems and method for ultrasound probe guidance are provided. One system includes a probe guide with a body having at least one engagement portion for coupling an ultrasound probe to the body. The system also includes at least one sensor configured to communicate with an ultrasound imaging system, wherein the at least one sensor coupled to the body and configured to determine at least one of a spatial position, an orientation, a probe head movement speed, a temperature, a scan speed of the body relative to an object being scanned, or a contact pressure relative to the body and the object being scanned.

Abstract: The present approach generally relates to systems and methods for implementing energy modulated tomographic imaging of nanoparticles. In certain embodiments, a first energy is used to activate probe particles labeling an anatomy or tissue of interest. The probe particles, once activated, emit photons at a different rate and/or spectrum in response to an underlying physiological event, such as action potentials propagating in the labeled anatomy or tissue. The emitted photons may then be detected and used to map or image the occurrence of the physiological event.

Abstract: Optoelectronic devices with enhanced internal outcoupling include a substrate, an anode, a cathode, an electroluminescent layer, and an electron transporting layer comprising inorganic nanoparticles dispersed in an organic matrix.

Abstract: The present techniques provide methods and systems for recording micro-holograms on a holographic disk using a plurality of counter-propagating light beams in parallel. The parallel counter-propagating light beams overlap to form interference patterns on a data layer and over multiple data tracks in the holographic disk. Rotating the disk enables the parallel recording of micro-holograms over multiple data tracks, thus reducing recording time. Further, the illumination pattern may include illuminated spots and non-illuminated regions, such that each illumination spot may cover a relatively small fraction of the data layer plane, possibly controlling the depth spread of the recorded micro-hologram. In some embodiments, data in the parallel signal beams may be retrieved from a master holographic disk or may be modulated into the parallel signal beams.

Abstract: A method for treatment of coke wastewater, including (1) introducing wastewater into a regulating reservoir into which an acid liquor is added until the pH value of the wastewater ranges between about 5.5 and about 6.5; (2) introducing the wastewater into a three-dimensional electrode treatment device for electrolysis treatment; and (3) introducing the wastewater into a coagulation reaction tank into which an alkali liquor is added until the pH value of the wastewater ranges between 8 and 10, and as a coagulant polysilicate ferric magnesium is added into the wastewater for a hybrid reaction of between 5 and 15 mins; allowing the wastewater to flow into a sedimentation basin for plain sedimentation of between 4 and 6 hrs; and extracting a supernatant liquor to yield a processed effluent.

Abstract: A system and method of operating a dual-beam detection system of a holographic data storage disc, including: impinging a data beam on a data layer of the holographic data storage disc; impinging a tracking beam on a tracking element of the holographic data storage disc; detecting a reflection of the tracking beam from the tracking element; and coordinating position of the data beam relative to the tracking beam.

Abstract: Techniques are provided for increasing spectral efficiency over data channels in a storage or communication system. In some embodiments, data may be encoded and transmitted over multiple channels. The transmitted data from the multiple channels may be considered together as a channel bundle, thereby increasing the edge transitions of the group of signals to improve clock recovery and reduce coding constraints. In some embodiments, the channel bit size is reduced to maximize data rates based on the reduced coding constraints. Furthermore, the channel bundle has only one channel with timing markers, so that a receiver may receive information from the channel bundle and recover clocking based on the timing markers in the one channel.