Abstract: Example methods and apparatus for determining a timing advance are described. One example method includes obtaining ephemeris information of a satellite, where the ephemeris information includes coordinates of the satellite and an ephemeris error of the satellite. A timing advance is determined according to a preset rule based on the ephemeris information and location information of a terminal device, where the location information includes coordinates of the terminal device and a positioning error of the terminal device. The preset rule is determined by using a first horizontal distance, a first vertical distance, the ephemeris error, and the positioning error.

Abstract: The invention provides an N-benzyl-N-arylsulfonamide derivative, which is an N-benzyl-N-arylsulfonamide compound represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof. The N-benzyl-N-arylsulfonamide derivative is obtained by condensing a substituted nitrobenzene with 5- or 6-membered nitrogen-containing aliphatic heterocycle (the ring B), reducing the nitro group to an amino group, and subjecting the amino group to reductive amination, sulfonamidation; or by subjecting a substituted nitrobenzene to nitro reduction, reductive amination and sulfonamidation, and condensing the resultant intermediate with 5- or 6-membered nitrogen-containing aliphatic heterocycle (the ring B). It has been experimentally demonstrated that the N-benzyl-N-arylsulfonamide derivative of the invention can specifically bind to Kv1.3 potassium channel and inhibit or decrease its activity, and is useful in the treatment of autoimmune diseases caused by abnormal activation of the Kv1.

Abstract: Embodiments of this application provide a side information transmission method and apparatus. Data to be transmitted by a transmit end includes at least one first data sub-block and at least one second data sub-block. A first modulated signal is obtained based on a first phase rotation factor. A second modulated signal is obtained based on a second phase rotation factor. Side information is generated based on the first phase rotation factor and the second phase rotation factor. The first data sub-block is carried on a first subcarrier, and the side information is also mapped to the first carrier. The first modulated signal corresponding to the at least one first data sub-block, the second modulated signal corresponding to the at least one second data sub-block, and a modulated signal corresponding to the side information are superposed to obtain a to-be-transmitted signal.

Abstract: A phototherapy apparatus with interactive user interface for treating biological tissue of an animal or human target. The user interface comprises intuitive graphic menus which allow the clinicians or practitioners to define the properties of the biological tissue through easily observable physical characteristics such as weight, skin color, and hair color of the patient. The central control unit of the phototherapy apparatus then automatically optimizes the parameters of the light source according to the properties of the biological tissue and generates an appropriate treatment protocol to produce the optimum phototherapy result.

Abstract: The present disclosure discloses a mutant of a lycopene epsilon cyclase (Lcye) gene crucial in a wheat carotenoid synthesis pathway and use thereof. The present disclosure provides the following proteins: (1) a protein obtained by substituting serine at position 253 of an Lcye-D1 protein with phenylalanine; (2) a derived protein that is obtained by subjecting the protein in (1) to substitution and/or deletion and/or addition of one or more amino acid residues and has the same ability as the protein in (1); (3) a protein that has a homology of more than 99%, more than 95%, more than 90%, more than 85%, or more than 80% with the amino acid sequence defined in any one of (1) and (2) and has the same function as the amino acid sequence; and (4) a fusion protein obtained by attaching a tag to N-terminus and/or C-terminus of the protein in any one of (1) to (3).

Abstract: The present application provides use of Monascinol in preparation of a fat-reducing product, a method for preventing or treating a disease related to abnormal lipid metabolism, and a fat-reducing product including Monascinol. The fat-reducing product includes a fat-reducing functional food and a fat-reducing drug, the fat-reducing functional food is used for preventing or improving a sub-health state related to obesity in an individual, the fat-reducing drug is used for preventing or treating a disease related to abnormal lipid metabolism in an individual. It is found that in the solution of the present application the Monascinol has new functions of significantly lowering blood lipid, controlling weight gain, and inhibiting body fat accumulation; and has low cytotoxicity, thereby having high use safety when serving as a fat-reducing product.

Abstract: This invention discloses a cold plasma therapy device with enhanced safety. The plasma therapy device comprises a dielectric barrier made of a material with high dielectric constant (i.e., relative permittivity). Hence the thickness of the dielectric barrier can be increased to produce similar plasma intensity in comparison to a dielectric barrier with a low dielectric constant. The increased thickness enhances the mechanical durability of the dielectric barrier. When the thickness of the dielectric barrier is larger than the maximum discharge gap of the ambient air (or the supplied gas medium) under the voltage applied, no arc discharge will be produced even when there is a crack across the thickness of the dielectric barrier. This minimizes the risk of subject tissue damage from possible electric shocks.

Abstract: A phototherapy apparatus with interactive user interface for treating biological tissue of an animal or human target. The user interface comprises intuitive graphic menus which allow the clinicians or practitioners to define the properties of the biological tissue through easily observable physical characteristics such as weight, skin color, and hair color of the patient. The central control unit of the phototherapy apparatus then automatically optimizes the parameters of the light source according to the properties of the biological tissue and generates an appropriate treatment protocol to produce the optimum phototherapy result.

Abstract: There is provided a phototherapy apparatus, in which the therapeutic light is delivered through or in proximity to one or more massage components. The massage component provides mechanical massage to the subject biological tissue and modifies the properties of the subject tissue in thickness, density, etc. to facilitate the absorption of the therapeutic light and enhance the effect of the phototherapy procedure.

Abstract: This invention discloses a reconfigurable cold plasma therapy device with enhanced safety. The plasma therapy device comprises a dielectric barrier discharge (DBD) probe connected to a high voltage power supply, which supplies a high voltage to the DBD probe. The DBD probe comprises a handle having a designated handling area for the operator, whose material and thickness are selected such that when the high voltage is supplied to the DBD probe, the voltage charged onto the body of the operator is below a safety voltage. The low voltage prevents spark generation even when the operator is in close proximity to conductive subjects. As an additional feature, the dielectric barrier of the DBD probe is switchable, allowing both the material and the thickness of the dielectric barrier to be changed to control the property of the plasma discharge for treating different medical conditions.

Abstract: This invention discloses a DBD plasma therapy device with replaceable dielectric barrier for treating different patients with different medical conditions. The plasma therapy device is equipped with a variety of dielectric barriers. The dielectric barriers may have different electrical characteristics (which are determined by their materials as well as physical dimensions and shapes) to adapt for the treatment of different types of biological tissues. The dielectric barrier of the plasma therapy device can be replaced to avoid contamination and cross-infection. As an additional feature, the plasma device further comprises an optical sensor, such as a spectroscopic sensor, for monitoring the emission spectrum of the plasma discharge. The emission spectrum can be utilized to analyze the composition of the reactive species generated by the plasma discharge and provide feedback control to the plasma therapy device.

Abstract: There is provided a phototherapy apparatus, in which the therapeutic light is delivered through or in proximity to one or more massage components. The massage component provides mechanical massage to the subject biological tissue and modifies the properties of the subject tissue in thickness, density, etc. to facilitate the absorption of the therapeutic light and enhance the effect of the phototherapy procedure.

Abstract: The present invention embodies a technique, referred to as Secure QR Codes, which not only provides aesthetically enhanced QR codes but also allows for security. It can embed a standard black and white QR code, referred to as a public QR code, and a secret QR code, both into a secure QR code. The secure QR code produced is composed of colored cells. The public black and white QR code must first be, either aesthetically enhanced into an enhanced colored QR code, or transformed into a colored QR code with cells of uniform color obtained by transforming each of the black and white cells of the public QR code into cells that takes a color from a subset of possible colors, such that the luminance of each colored cell approximates accurately the black or white luminance values of the public QR code.

Abstract: There is provided a phototherapy apparatus, in which the therapeutic light is delivered through one or more massage components. The massage component provides mechanical massage to the subject biological tissue and modifies the properties of the subject tissue in thickness, density, etc. to facilitate the absorption of the therapeutic light and enhance the effect of the phototherapy procedure. The light source of the phototherapy apparatus is actively cooled by a synthetic jet cooler.

Abstract: This invention discloses a method for material identification by analyzing the LIBS spectrum of the sample. The LIBS spectrum is pre-processed to equalize the contribution of elements with strong and weak emission lines. In the meantime, the number of spectral variables is reduced to enhance the specificity and minimize the influence of instrument noise. Commonly used spectrum identification and library search algorithms are then applied to the pre-processed LIBS spectrum for material identification.

Abstract: There is provided a phototherapy apparatus, in which the therapeutic light is delivered through one or more massage components. The massage component provides mechanical massage to the subject biological tissue and modifies the properties of the subject tissue in thickness, density, etc. to facilitate the absorption of the therapeutic light and enhance the effect of the phototherapy procedure. The light source of the phototherapy apparatus is actively cooled by a synthetic jet cooler.

Abstract: Disclosed are a method and apparatus for embedding a graphic representation into a two dimensional matrix code by modifying the luminance of individual pixels in the image according the values of a provided QR code image. The modified luminance values are determined by an optimization procedure which minimizes a visual distortion metric with respect to the original graphic representation while maintaining the value of a model for the probability of decoding and detection error below a specified limit.

Abstract: A phototherapy apparatus with interactive user interface for treating biological tissue of an animal or human target. The user interface comprises intuitive graphic menus which allow the clinicians or practitioners to define the properties of the biological tissue through easily observable physical characteristics such as weight, skin color, and hair color of the patient. The central control unit of the phototherapy apparatus then automatically optimizes the parameters of the light source according to the properties of the biological tissue and generates an appropriate treatment protocol to produce the optimum phototherapy result.

Abstract: There is provided a phototherapy apparatus, in which the therapeutic light is delivered through or in proximity to one or more massage components. The massage component provides mechanical massage to the subject biological tissue and modifies the properties of the subject tissue in thickness, density, etc. to facilitate the absorption of the therapeutic light and enhance the effect of the phototherapy procedure.

Abstract: There is provided a phototherapy apparatus, in which the therapeutic light is delivered through or in proximity to one or more massage components. The massage component provides mechanical massage to the subject biological tissue and modifies the properties of the subject tissue in thickness, density, etc. to facilitate the absorption of the therapeutic light and enhance the effect of the phototherapy procedure.