Patents by Inventor Xiaomei Lu

Xiaomei Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132492
    Abstract: The present disclosure provides a class of Pyridopyrimidine compounds having a structure shown in Formula (I) or their pharmaceutically acceptable salts, or stereoisomers or prodrug molecules and applications thereof. The compounds in the present disclosure can efficiently and selectively degrade AKT3 protein in cells without affecting AKT1/2, thereby significantly inhibiting tumor cell proliferation mediated by high expression of AKT3 protein. It can be used to prepare therapeutic drugs for cancer and other diseases related to abnormal expression of AKT3 protein.
    Type: Application
    Filed: September 6, 2023
    Publication date: April 25, 2024
    Applicants: JINAN UNIVERSITY, SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES
    Inventors: Ke DING, Xin ZHANG, Fang XU, Xiaomei REN, Xiaoyun LU, Dawei MA, Weixue HUANG
  • Patent number: 9903943
    Abstract: Disclosed is a method of estimating the distance between two nodes.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: February 27, 2018
    Assignee: RICOH COMPANY, LTD.
    Inventors: Xiaomei Lu, Bin Da, Wei Wang, Linju Yang, Ke Liao
  • Publication number: 20160131750
    Abstract: Disclosed is a method of estimating the distance between two nodes.
    Type: Application
    Filed: October 29, 2015
    Publication date: May 12, 2016
    Applicant: RICOH COMPANY, LTD.
    Inventors: Xiaomei Lu, Bin Da, Wei Wang, Linju Yang, Ke Liao
  • Patent number: 7269133
    Abstract: The HA IS-IS system provides a redundant backup IS-IS protocol instance that can seamlessly assume the function of the active IS-IS instance in the event of active MCP failure. Once the backup is online, the active synchronizes its global, interface, adjacency, neighbor, and LSP system state information. In the ongoing synchronization phase, the active and the backup maintain synchronization using a combination of explicit message updates from active to backup together with message flow-through. In the recovery phase, the operating system detects the failure of the active and notifies the backup, which assumes the active function as a standalone system without reconfiguring or interrupting traffic among peer network routers, and starts computing forwarding tables and updating routing tables.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: September 11, 2007
    Inventors: Xiaomei Lu, Ronald P. Folkes, Lance A. Visser
  • Publication number: 20040042395
    Abstract: The HA IS-IS system provides a redundant backup IS-IS protocol instance that can seamlessly assume the function of the active IS-IS instance in the event of active MCP failure. Once the backup is online, the active synchronizes its global, interface, adjacency, neighbor, and LSP system state information. In the ongoing synchronization phase, the active and the backup maintain synchronization using a combination of explicit message updates from active to backup together with message flow-through. In the recovery phase, the operating system detects the failure of the active and notifies the backup, which assumes the active function as a standalone system without reconfiguring or interrupting traffic among peer network routers, and starts computing forwarding tables and updating routing tables.
    Type: Application
    Filed: September 3, 2002
    Publication date: March 4, 2004
    Inventors: Xiaomei Lu, Ronald P. Folkes, Lance A. Visser