Abstract: The present disclosure provides adamantyl compounds having one or more amine groups and one or more nitrate groups. The aminoadamantyl nitrate compounds can be used to treat disorders of the central nervous system, including neurodegenerative and non-neurodegenerative diseases.

Abstract: A magnetic resonance imaging (MRI) contrast agent and a preparation method and a use thereof is provided, which belong to the technical field of Magnetic Resonance Imaging contrast agent. The MRI contrast agent is prepared by the compound having a structure of formula I; and it also may include the compound having a structure of formula II or a pharmaceutically acceptable salt thereof, wherein M1 is a divalent ion or a trivalent ion of a paramagnetic metal selected from Mn, Fe, Eu, or Dy; M2 is selected from Na+, K+ or meglumine cation; when M1 is a divalent ion, a is 2; when M1 is a trivalent ion, a is 3. The MRI contrast agent has good water solubility, high relaxivity, and low toxic and side effect.

Abstract: A system for simultaneously and microscopically measuring vapor cell coating film energy transfer and relaxation characteristics at nanometer scales includes a space relaxation characteristic detection unit which includes a laser, an optical isolator, a spatial light filter, a reflector, a Glan-Taylor polarizer, a first quarter-wave plate, a spatial light modulator, a focusing lens, a second quarter-wave plate, a polarizing film, a PD detection unit, an I/V amplification unit, a data acquisition unit, a spectroscope and an optical chopper, an atomic force microscope detection unit for energy transfer micro-areas, a shielding cylinder, a coated alkali metal atomic vapor cell, a data processing unit and a magnetic field controlled coil.

Abstract: A novel power slide with a motor directly connected to a lead screw includes a left slide and a right slide each including a top rail, a bottom rail, a power motor, a lead screw, a threaded assembly and a retainer ring. A first slot and a second slot are formed in two ends of the top rail, respectively. The power motor is fixed to a lower surface of the top rail through a motor bracket. The lead screw has an end connected to the power motor and another end rotatably fixed to the lower surface of the top rail. A bottom portion of the threaded assembly is fixedly connected to an upper surface of the bottom rail, and the lead screw horizontally penetrates through the threaded assembly and is in threaded fit with the threaded assembly. The retainer ring is located in the first slot, and a gap is formed between the retainer ring and the first slot.

Abstract: Methods and systems to automatically respond to a request for product information are described. In one embodiment, a data collection module may collect product data over a network, identify that the product data is related to a particular product, and store the product data and an association between the product data and the particular product in a database. An instant messaging engine may receive a request for the product data after the product data is stored in the database and an interpreter module may identify, in response to the request, the request to correspond to the particular product and retrieve the product data based on the association between the particular product and the product data. The instant messaging engine may also transmit, using an instant messaging protocol, a response to the request, the response including the product data.

Abstract: Technologies for filtering notification content based on event type are provided. The disclosed techniques include causing a plurality of notifications to be presented on a computing device, where the plurality of notifications includes a first notification of a first event type and a second notification of a second event type that is different than the first event type. A plurality of filters is caused to be presented on the computing device, where the plurality of filters includes a first filter that is associated with one or more first event types and a second filter that is associated with one or more second event types. An input that selects the first filter is then received. In response to receiving the input, the one or more first event types are identified. A strict subset of the plurality of notifications that are of one or more of the one or more first event types is identified from among the plurality of notifications.

Abstract: Methods and systems to automatically respond to a request for product information are described. In one embodiment, a data collection module may collect product data over a network, identify that the product data is related to a particular product, and store the product data and an association between the product data and the particular product in a database. An instant messaging engine may receive a request for the product data after the product data is stored in the database and an interpreter module may identify, in response to the request, the request to correspond to the particular product and retrieve the product data based on the association between the particular product and the product data. The instant messaging engine may also transmit, using an instant messaging protocol, a response to the request, the response including the product data.

Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.

Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.

Abstract: The present disclosure provides adamantyl compounds having one or more amine groups and one or more nitrate groups. The aminoadamantyl nitrate compounds can be used to treat disorders of the central nervous system, including neurodegenerative and non-neurodegenerative diseases.

Abstract: Provided are a lock cylinder and an unlocking key. The lock cylinder includes: a lock housing; a lock core, herein the lock core is rotatably arranged in the lock housing; a locking member, herein the locking member is movably arranged between the lock core and the lock housing and provided with a locking position and an unlocking position; a locking blade, herein the locking blade is movably connected to the lock core and capable of stopping or avoiding the movement of the locking member so as to lock or unlock the locking member; a driving assembly, herein at least part of the driving assembly is movably arranged relative to the locking member, and the driving assembly is capable of stopping or avoiding the movement of the locking member so as to lock or unlock the locking member.

Abstract: A method for removing an undesired coating from a front face of a crystalline silicon solar cell includes: S1: depositing an Al2O3 film, an SiO2 film, and an SiNx film on a back face of a silicon wafer to form a backside passivation film, and forming an undesired coating on an edge of the front face of the silicon wafer; S2: preparing an aqueous film on a surface of the backside passivation film of the product obtained in S1; S3: passing the product obtained in S2 through an acid tank to remove the undesired coating; S4: passing the product obtained in S3 through a water tank to remove a residual treatment solution; and S5: drying the product obtained in S4.

Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.

Abstract: A system for simultaneously and microscopically measuring vapor cell coating film energy transfer and relaxation characteristics at nanometer scales includes a space relaxation characteristic detection unit which includes a laser, an optical isolator, a spatial light filter, a reflector, a Glan-Taylor polarizer, a first quarter-wave plate, a spatial light modulator, a focusing lens, a second quarter-wave plate, a polarizing film, a PD detection unit, an I/V amplification unit, a data acquisition unit, a spectroscope and an optical chopper, an atomic force microscope detection unit for energy transfer micro-areas, a shielding cylinder, a coated alkali metal atomic vapor cell, a data processing unit and a magnetic field controlled coil.

Abstract: A complex surface three-coordinate measuring device includes a three-degree-of-freedom motion platform and a force control probe, the force control probe is fixedly mounted on the Z-axis sliding block, which is in the same direction as the X-axis direction and used to contact with the workpiece surface with constant force. A six-axis force sensor is used to collect the contact force between the stylus and the workpiece surface. In this method, the force control is realized in the measurement to make the stylus in constant force contact with the workpiece surface. The error compensation direction is determined according to the direction of the contact force, and then the effective radius of the stylus spherical head is compensated in this direction, thus the actual contact point of stylus and workpiece can be obtained.

Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.

Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.

Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.

Abstract: A system server includes a database of two-dimensional images and a processor coupled to a hardware memory with instructions that in response to execution by the processor direct performance of operations. The operations include generating a digital model from the images in the database and communicating a first portion of the digital model as an enhanced view to a user device. The first portion corresponds to a first line of sight orientation of the user device as measured by an orientation sensor. The operations include receiving a signal based on sensor data measured by the orientation sensor. The signal indicates movement of the user device from the first line of sight orientation to a second line of sight orientation. In response, the method includes communicating a second portion of the digital model to the user device that corresponds to the second line of sight orientation of the user device.

Abstract: A method and a device for transaction clearing are used to increase clearing flexibility and reduce server load pressure. The method includes receiving first clearing requests transmitted by a quantity N of terminals, where N>1 (201); according to the first clearing requests, acquiring transaction data of the quantity N of terminals from a database (202); initializing a cache queue, and loading the transaction data into the cache queue (203); reading the transaction data in the cache queue, and performing a clearing process on the transaction data (204); and writing a clearing result into the database and feeding back the terminals with an execution result of the first clearing requests (205).