Patents by Inventor Xiaoxin Chen

Xiaoxin Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10558327
    Abstract: Provided are a method and device for updating an input method system, a computer storage medium, and a device. The method includes: receiving multiple operation logs from multiple user terminals on which the input method system is installed, the operation logs recording log entries which indicate an operations of input corresponding candidate items; extracting log entries from the received operation logs; determining a quantity of log entries of each type; and sending, according to the determined quantity, log entries in a preset type to the user terminals on which the input method system is installed, so as to update the input method system.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: February 11, 2020
    Assignee: BAIDU ONLINE NETWORK TECHNOLOGY (BEIJING) CO., LTD.
    Inventors: Xianchao Wu, Chuang Wu, Xiaoxin Chen, Long Chen, Mianmian Wen
  • Publication number: 20200024235
    Abstract: Disclosed are a crystal form and a salt form of and a preparation method for a tyrosine kinase inhibitor.
    Type: Application
    Filed: September 29, 2017
    Publication date: January 23, 2020
    Inventors: Chaofeng Long, Zhengxia Chen, Xiaoxin Chen, Yang Zhang, Zhuowei Liu, Shuhui Chen, Jian Li
  • Patent number: 10532053
    Abstract: A compound represented by Formula I or pharmaceutically acceptable salt thereof. The present invention relates to a 4-arylamino quinazoline hydroxamic acid compound having a histone deacetylase inhibitory activity, preparation method of the compound, pharmaceutical composition comprising the compound, and use of the compound and the pharmaceutical composition in the preparation of a histone deacetylase inhibitor medicine. The present invention aims at acquiring, via a medicine design and a synthetic technology, a series of selective histone deacetylase inhibitors having good hypotype selectivity and favorable pharmacokinetic characteristics based on optimization of an enzyme surface recognition region and connection region of 4-arylamino quinazoline, thus reducing an effect on normal tissues or cells while improving an antineoplastic activity of the normal tissues or cells. In Formula I, the variables are as described herein.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: January 14, 2020
    Assignee: Guangdong Zhongsheng Pharmaceutical Co., Ltd
    Inventors: Lijuan Chen, Chaofeng Long, Xiaoxin Chen, Zhuowei Liu, Haoyu Ye, Chenshi Xie
  • Patent number: 10526320
    Abstract: The present invention discloses a class of pyrrolidine derivatives as PPAR agonist, and their use for the treatment of some diseases of PPAR receptor-associated pathways (such as nonalcoholic steatohepatitis and concurrent fibrosis, insulin resistance, primary biliary cholangitis, dyslipidemia, hyperlipidemia, hypercholesterolemia, atherosclerosis, hypertriglyceridemia, cardiovascular disease, obesity or the like). In particular, the present invention discloses a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: January 7, 2020
    Assignee: GUANGDONG RAYNOVENT BIOTECH CO., LTD.
    Inventors: Zhiliang Yuan, Chaofeng Long, Zhigan Jiang, Xiaoxin Chen, Haiying He, Xing Liu, Xiao Zhang, Zhiqiang Liu, Yan Wang, Leilei Gao, Zhen Gong, Jian Li, Shuhui Chen
  • Patent number: 10399981
    Abstract: The invention discloses a crystal form A of a compound (I) and a preparation method thereof, and further discloses an application of the crystal form A as a PDE2 or TNF-? inhibitor.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: September 3, 2019
    Assignee: GUANGDONG RAYNOVENT BIOTECH CO., LTD.
    Inventors: Lingyun Wu, Chaofeng Long, Peng Zhang, Xiaoxin Chen, Li Zhang, Zhuowei Liu, Zheng Wang, Shuhui Chen, Lijuan Chen
  • Publication number: 20190225597
    Abstract: The present invention discloses a class of pyrrolidine derivatives as PPAR agonist, and their use for the treatment of some diseases of PPAR receptor-associated pathways (such as nonalcoholic steatohepatitis and concurrent fibrosis, insulin resistance, primary biliary cholgangitis, dyslipidenmia, hyperlipidemia, hypercholesterolemia, atherosclerosis, hypertriglyceridemia, cardiovascular disease, obesity or the like). In particular, the present invention discloses a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 12, 2017
    Publication date: July 25, 2019
    Inventors: Zhiliang Yuan, Chaofeng Long, Zhigan Jiang, Xiaoxin Chen, Haiying He, Xing Liu, Xiao Zhang, Zhiqiang Liu, Yan Wang, Leilei Gao, Zhen Gong, Jian Li, Shuhui Chen
  • Patent number: 10278973
    Abstract: Disclosed are a series of hydroxyl purine compounds and the use thereof as PDE2 or TNF? inhibitors, in particular, the compounds as shown in formula (I), or tautomers thereof or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: May 7, 2019
    Assignee: GUANGDONG RAYNOVENT BIOTECH CO., LTD.
    Inventors: Lingyun Wu, Xiaoxin Chen, Peng Zhang, Xing Liu, Li Zhang, Zhuowei Liu, Shuhui Chen, Chaofeng Long
  • Publication number: 20190119217
    Abstract: The present invention relates to a tyrosine kinase inhibitor and a pharmaceutical composition comprising same.
    Type: Application
    Filed: April 7, 2016
    Publication date: April 25, 2019
    Inventors: Chaofeng LONG, Zhengxia CHEN, Xiaoxin CHEN, Yang ZHANG, Zhuowei LIU, Peng LI, Shuhui CHEN, Guibai LIANG, Cheng XIE, Zhengwei LI, Zhifei FU, Guoping HU, Jian LI
  • Patent number: 10241819
    Abstract: Virtualization software establishes multiple execution environments within a virtual machine, wherein software modules executing in one environment cannot access private memory of another environment. A separate set of shadow memory address mappings is maintained for each execution environment. For example, a separate shadow page table may be maintained for each execution environment. The virtualization software ensures that the shadow address mappings for one execution environment do not map to the physical memory pages that contain the private code or data of another execution environment. When execution switches from one execution environment to another, the virtualization software activates the shadow address mappings for the new execution environment. A similar approach, using separate mappings, may also be used to prevent software modules in one execution environment from accessing the private disk space or other secondary storage of another execution environment.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: March 26, 2019
    Assignee: VMware, Inc.
    Inventors: Xiaoxin Chen, Carl A. Waldspurger, Pratap Subrahmanyam
  • Publication number: 20190004850
    Abstract: A virtual-machine-based system that identifies an application or process in a virtual machine in order to locate resources associated with the identified application. Access to the located resources is then controlled based on a context of the identified application. Those applications without the necessary context will have a different view of the resource.
    Type: Application
    Filed: August 13, 2018
    Publication date: January 3, 2019
    Inventors: Xiaoxin CHEN, Carl A. WALDSPURGER, Pratap SUBRAHMANYAM
  • Patent number: 10169253
    Abstract: A virtual-machine-based system that may protect the privacy and integrity of application data, even in the event of a total operating system compromise. An application is presented with a normal view of its resources, but the operating system is presented with an encrypted view. This allows the operating system to carry out the complex task of managing an application's resources, without allowing it to read or modify them. Different views of “physical” memory are presented, depending on a context performing the access. An additional dimension of protection beyond the hierarchical protection domains implemented by traditional operating systems and processors is provided.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: January 1, 2019
    Inventors: Xiaoxin Chen, Carl A. Waldspurger, Pratap Subrahmanyam, Tal Garfinkel, Dan Boneh
  • Publication number: 20180305361
    Abstract: The invention discloses a crystal form A of a compound (I) and a preparation method thereof, and further discloses an application of the crystal form A as a PDE2 or TNF-? inhibitor.
    Type: Application
    Filed: October 27, 2016
    Publication date: October 25, 2018
    Inventors: Lingyun WU, Chaofeng LONG, Peng ZHANG, Xiaoxin CHEN, Li ZHANG, Zhuowei LIU, Zheng WANG, Shuhui CHEN, Lijuan CHEN
  • Patent number: 10098885
    Abstract: Hydroxyl purine compounds represented by formula (I), tautomers or pharmaceutically acceptable salts thereof, and applications thereof as PDE2 or TNF-? inhibitors.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: October 16, 2018
    Assignee: GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD
    Inventors: Lingyun Wu, Chaofeng Long, Peng Zhang, Xiaoxin Chen, Li Zhang, Zhuowei Liu, Jian Li, Shuhui Chen
  • Publication number: 20180248270
    Abstract: An antenna and a communications device are disclosed. The antenna includes: multiple feeders, a microstrip antenna array, and at least one energy attenuation circuit; the microstrip antenna array includes multiple array elements, where each of the multiple array elements is connected to a cable feeding port by using one of the multiple feeders; each of the at least one energy attenuation circuit is located at a feeder, where the feeder is one of the multiple feeders and is connected to an array element, and the array element is located at a periphery of the multiple array elements; and the energy attenuation circuit includes a resistor, where the resistor is grounded, and the resistor consumes a part of energy in the feeder when the resistor is grounded.
    Type: Application
    Filed: February 15, 2018
    Publication date: August 30, 2018
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Feng DING, Kun ZHANG, Xiaoxin CHEN
  • Patent number: 10048982
    Abstract: A virtual-machine-based system that identifies an application or process in a virtual machine in order to locate resources associated with the identified application. Access to the located resources is then controlled based on a context of the identified application. Those applications without the necessary context will have a different view of the resource.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: August 14, 2018
    Assignee: VMware, Inc.
    Inventors: Xiaoxin Chen, Carl A. Waldspurger, Pratap Subrahmanyam
  • Publication number: 20180148451
    Abstract: Disclosed are a series of hydroxyl purine compounds and the use thereof as PDE2 or TNF? inhibitors, in particular, the compounds as shown in formula (I), or tautomers or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: May 5, 2016
    Publication date: May 31, 2018
    Inventors: Linyun WU, Xiaoxin CHEN, Peng ZHANG, Xing LIU, Li ZHANG, Zhuowei LIU, Shuhui CHEN, Chaofeng LONG
  • Publication number: 20180140607
    Abstract: Disclosed are a series of hydroxyl purine compounds and the use thereof as PDE2 or TNF? inhibitors, in particular, the compounds as shown in formula (I), or tautomers thereof or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: May 5, 2016
    Publication date: May 24, 2018
    Inventors: Lingyun WU, Xiaoxin CHEN, Peng ZHANG, Xing LIU, Li ZHANG, Zhuowei LIU, Shuhui CHEN, Chaofeng LONG
  • Publication number: 20180098990
    Abstract: A compound represented by Formula I or pharmaceutically acceptable salt thereof. The present invention relates to a 4-arylamino quinazoline hydroxamic acid compound having a histone deacetylase inhibitory activity, preparation method of the compound, pharmaceutical composition comprising the compound, and use of the compound and the pharmaceutical composition in the preparation of a histone deacetylase inhibitor medicine. The present invention aims at acquiring, via a medicine design and a synthetic technology, a series of selective histone deacetylase inhibitors having good hypotype selectivity and favorable pharmacokinetic characteristics based on optimization of an enzyme surface recognition region and connection region of 4-arylamino quinazoline, thus reducing an effect on normal tissues or cells while improving an antineoplastic activity of the normal tissues or cells.
    Type: Application
    Filed: March 17, 2016
    Publication date: April 12, 2018
    Inventors: Lijuan CHEN, Chaofeng LONG, Xiaoxin CHEN, Zhuowei LIU, Haoyu YE, Chenshi XIE
  • Patent number: 9938292
    Abstract: Disclosed are quinoline derivatives as hedgehog pathway inhibitors, especially as SMO inhibitors. Compounds of the present invention can be used in treating diseases relating to hedgehog pathway including cancer.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: April 10, 2018
    Assignee: Guangdong Zhongsheng Pharmaceutical Co., Ltd
    Inventors: Hao Wu, Chaofeng Long, Jun Lin, Xiaoxin Chen, Yunhui Li, Zhuowei Liu, Changqing Wei, Lijuan Chen, Shuhui Chen
  • Publication number: 20170344496
    Abstract: A virtual-machine-based system that may protect the privacy and integrity of application data, even in the event of a total operating system compromise. An application is presented with a normal view of its resources, but the operating system is presented with an encrypted view. This allows the operating system to carry out the complex task of managing an application's resources, without allowing it to read or modify them. Different views of “physical” memory are presented, depending on a context performing the access. An additional dimension of protection beyond the hierarchical protection domains implemented by traditional operating systems and processors is provided.
    Type: Application
    Filed: August 21, 2017
    Publication date: November 30, 2017
    Inventors: Xiaoxin CHEN, Carl A. WALDSPURGER, Pratap SUBRAHMANYAM, Tal GARFINKEL, Dan BONEH