Patents by Inventor Xiaoyang Dong

Xiaoyang Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic amides useful as protein modulators
    Patent number: 11970480
    Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Grant
    Filed: May 17, 2022
    Date of Patent: April 30, 2024
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Adam Kenneth Charnley, Michael G. Darcy, Jason W. Dodson, Xiaoyang Dong, Terry V. Hughes, Jianxing Kang, Lara Kathryn Leister, Yiqian Lian, Yue Li, John F. Mehlmann, Neysa Nevins, Joshi M. Ramanjulu, Joseph J. Romano, Gren Z. Wang, Guosen Ye, Daohua Zhang
  • Nitrogen Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors
    Publication number: 20240083896
    Abstract: Compounds of formula (I) are described, wherein each of the variable groups is as defined in the specification. Also described are pharmaceutical compositions containing a compound of formula (I), and uses of the compounds and pharmaceutical compositions for inhibiting Nav1.8 voltage-gated sodium channels and treating Nav1.8 mediated diseases, disorders, and conditions, such as pain and pain-associated diseases, disorders, and conditions and cardiovascular diseases, disorders, and conditions, such as atrial fibrillation.
    Type: Application
    Filed: December 16, 2021
    Publication date: March 14, 2024
    Applicant: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Xiaoyang DONG, Mark Andrew ELBAN, Jie GUANG, Ming-Hsun HO, Tram H. HOANG, Joseph J. ROMANO, David Glenn WASHBURN
  • Heterocyclic Amides Useful as Protein Modulators
    Publication number: 20230071675
    Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Application
    Filed: May 17, 2022
    Publication date: March 9, 2023
    Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Adam Kenneth CHARNLEY, Michael G DARCY, Jason W. DODSON, Xiaoyang DONG, Terry V. HUGHES, Jianxing KANG, Lara LEISTER, Yiqian LIAN, Yue LI, John F. MEHLMANN, Neysa NEVINS, Joshi M. RAMANJULU, Joseph J. ROMANO, Gren Z. WANG, Guosen YE, Daohua ZHANG
  • HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS AND METHODS OF USING THE SAME
    Publication number: 20210238172
    Abstract: The invention relates to combinations comprising a compound of the formula: or a salt thereof; and one or more additional pharmaceutically agents active against HIV, and methods of using the same.
    Type: Application
    Filed: October 4, 2018
    Publication date: August 5, 2021
    Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Adam Kenneth CHARNLEY, Michael Gerard DARCY, Jason W. DODSON, Xiaoyang DONG, David FAVRE, Terry Vincent HUGHES, Jianxing KANG, Lara Kathryn LEISTER, Yuehu LI, Yiqian LIAN, John F. MEHLMANN, Neysa NEVINS, Joshi M. RAMANJULU, Joseph J. ROMANO, Gren Z. WANG, Guosen YE, Daohua ZHANG
  • Amino quinazolines as kinase inhibitors
    Patent number: 10717711
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, and Z are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: July 21, 2020
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Adam K. Charnley, Xiaoyang Dong
  • AMINO QUINAZOLINES AS KINASE INHIBITORS
    Publication number: 20190194145
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: February 27, 2019
    Publication date: June 27, 2019
    Inventors: Adam K. CHARNLEY, Xiaoyang DONG
  • Interactive collectible card games with defense and offence team formations
    Patent number: 10322346
    Abstract: An interactive system is built upon networked computing devices and cloud computing technologies that enables two or more players to prepare for and engage in a battle on a common battle ground. Prior to initiation of the battle, a player can select one or more stationary units and deploy them, as a defense team, in a home territory for the purpose of obstructing the movement or attack of the opponent. During the battle, the player can deploy attacking units that move without further player intervention, to attack the opponent. A garrisoning mode may be turned on by the player, allowing the player to form and organize an offense team of attacking units because they start to move on their own. The option of forming both defense teams and offense teams, which will carry out their mission without further player intervention presents an attractive gameplay strategy.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: June 18, 2019
    Assignee: Gooody Entertainment Co., Ltd.
    Inventor: Xiaoyang Dong
  • INTERACTIVE COLLECTIBLE CARD GAMES WITH DEFENSE AND OFFENCE TEAM FORMATIONS
    Publication number: 20180296920
    Abstract: An interactive system is built upon networked computing devices and cloud computing technologies that enables two or more players to prepare for and engage in a battle on a common battle ground. Prior to initiation of the battle, a player can select one or more stationary units and deploy them, as a defense team, in a home territory for the purpose of obstructing the movement or attack of the opponent. During the battle, the player can deploy attacking units that move without further player intervention, to attack the opponent. A garrisoning mode may be turned on by the player, allowing the player to form and organize an offense team of attacking units because they start to move on their own. The option of forming both defense teams and offense teams, which will carry out their mission without further player intervention presents an attractive gameplay strategy.
    Type: Application
    Filed: April 21, 2017
    Publication date: October 18, 2018
    Inventor: Xiaoyang Dong
  • AMINO QUINAZOLINES AS KINASE INHIBITORS
    Publication number: 20180258056
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 14, 2018
    Publication date: September 13, 2018
    Inventors: Adam K. CHARNLEY, Xiaoyang DONG
  • Amino quinazolines as kinase inhibitors
    Patent number: 9994529
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, and Z are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: June 12, 2018
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam K. Charnley, Michael P. Demartino, Xiaoyang Dong, Patrick M. Eidam, Pamela A. Haile, Robert W. Marquis, Jr., Joshi M. Ramanjulu, Joseph J. Romano, Ami Lakdawala Shah, Robert R. Singhaus, Jr., Gren Wang
  • AMINO QUINAZOLINES AS KINASE INHIBITORS
    Publication number: 20170152233
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: February 14, 2017
    Publication date: June 1, 2017
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam K. CHARNLEY, Michael P. DEMARTINO, Xiaoyang DONG, Patrick M. EIDAM, Pamela A. HAILE, Robert W. MARQUIS, JR., Joshi M. RAMANJULU, Joseph J. ROMANO, Ami Lakdawala SHAH, Robert R. SINGHAUS, JR., Gren WANG
  • Quinazolines as kinase inhibitors
    Patent number: 9650364
    Abstract: Disclosed are compounds that are inhibitors of RIP2 kinase and methods of making and using the same.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: May 16, 2017
    Assignee: GlaxoSmithKline Intellectual Property Development Limted
    Inventors: Linda N. Casillas, Adam Kenneth Charnley, Xiaoyang Dong, Pamela A. Haile, Michael P. Demartino, John F. Mehlmann
  • Amino quinazolines as kinase inhibitors
    Patent number: 9604938
    Abstract: Disclosed are compounds having the formula (Formula I)): wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: March 28, 2017
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam K. Charnley, Michael P. Demartino, Xiaoyang Dong, Patrick M. Eidam, Pamela A. Haile, Robert W. Marquis, Jr., Joshi M. Ramanjulu, Joseph J. Romano, Ami Lakdawala Shah, Robert R. Singhaus, Jr., Gren Wang
  • AMINO-QUINOLINES AS KINASE INHIBITORS
    Publication number: 20160060222
    Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: November 6, 2015
    Publication date: March 3, 2016
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam Kenneth CHARNLEY, Michael P. DeMARTINO, Xiaoyang DONG, Patrick EIDAM, Pamela A. HAILE, Philip Anthony HARRIS, Ami Lakdawala SHAH, Bryan W. KING, Robert W. MARQUIS, JR., John F. MEHLMANN, Joseph J. ROMANO, Clark A. SEHON
  • QUINAZOLINES AS KINASE INHIBITORS
    Publication number: 20150361069
    Abstract: Disclosed are compounds that are inhibitors of RIP2 kinase and methods of making and using the same.
    Type: Application
    Filed: February 19, 2014
    Publication date: December 17, 2015
    Inventors: Linda N. CASILLAS, Adam Kenneth CHARNLEY, Xiaoyang DONG, Pamela A. HAILE, Michael P. DEMARTINO, John F. MEHLMANN
  • AMINO QUINAZOLINES AS KINASE INHIBITORS
    Publication number: 20140206688
    Abstract: Disclosed are compounds having the formula (Formula I)): wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: August 17, 2012
    Publication date: July 24, 2014
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam K. Charnley, Michael P. Demartino, Xiaoyang Dong, Patrick M. Eidam, Pamela A. Haile, Robert W. Marquis, JR., Joshi M. Ramanjulu, Joseph J. Romano, Ami Lakdawala Shah, Robert R. Singhaus, JR., Gren Wang
  • AMINO-QUINOLINES AS KINASE INHIBITORS
    Publication number: 20130053375
    Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 6, 2011
    Publication date: February 28, 2013
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Michael P. DeMartino, Xiaoyang Dong, Patrick Eidam, Pamela A. Haile, Philip Anthony Harris, Ami Lakdawala Shah, Bryan W. King, Robert W. Marquis, JR., John F. Mehlmann, Joseph J. Romano, Clark A. Sehon