Patents by Inventor Xifang Wang

Xifang Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Beta-amino acids
    Patent number: 8772450
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: July 8, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • BETA-AMINO ACIDS
    Publication number: 20130023644
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: May 3, 2012
    Publication date: January 24, 2013
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • Beta-amino acids
    Publication number: 20070123709
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: July 7, 2006
    Publication date: May 31, 2007
    Inventors: Samuel Gellman, Daniel Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • Fibrin targeted therapeutics
    Publication number: 20070111947
    Abstract: Fibrin targeted therapeutic agents for the treatment of thromboembolism, infection, and cancer are provided.
    Type: Application
    Filed: October 16, 2006
    Publication date: May 17, 2007
    Inventors: Thomas McMurry, Andrew Kolodziej, Alan Carpenter, Simon Jones, Philip Graham, Richard Looby, Shrikumar Nair, Xifang Wang, Kirsten Overoye-Chan, John Barrett
  • Peptide-based multimeric targeted contrast agents
    Patent number: 6991775
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: January 31, 2006
    Assignee: Epix Medical, Inc.
    Inventors: Steffi K. Koerner, Andrew Kolodziej, Thomas J. McMurry, Shrikumar Nair, Alexander L. Nivorozhkin, Wei-Chuan Sun, Xifang Wang
  • Antimicrobial compositions containing &bgr;-amino acid oligomers
    Patent number: 6683154
    Abstract: Disclosed are antimicrobial compositions containing &bgr;-peptides and methods of inhibiting microbial growth in mammals using the compositions. The &bgr;-peptides present in the compositions contain ring structures in the peptide backbone which limit the conformational flexibility of the peptide backbone.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: January 27, 2004
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel Helmer Gellman, Bernard Weisblum, Emilie Ann Porter, Xifang Wang
  • Peptide-based multimeric targeted contrast agents
    Publication number: 20030216320
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Application
    Filed: July 30, 2002
    Publication date: November 20, 2003
    Inventors: Steffi K. Koerner, Andrew Kolodziej, Thomas J. McMurry, Shrikumar Nair, Alexander L. Nivorozhkin, Wei-Chuan Sun, Xifang Wang
  • &bgr;-polypeptide foldamers of well-defined secondary structure
    Patent number: 6613876
    Abstract: Disclosed are &bgr;-peptides containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the &agr; and &bgr; carbons of the peptide backbone. The &bgr;-peptides adopt stable helical and sheet structures in both the solid state and in solution. Method of generating combinatorial libraries of peptides containing &bgr;-peptide residues and the libraries formed thereby are disclosed.
    Type: Grant
    Filed: December 15, 1999
    Date of Patent: September 2, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Daniel H. Appella, Laurie A. Christianson, Daniel A. Klein, Susanne Krauthäuser, Yong Jun Chung, Xifang Wang
  • Beta-amino acids
    Publication number: 20020037997
    Abstract: Disclosed are &bgr;-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the &agr; and &bgr; carbons of the peptide backbone and &bgr;-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the &bgr;-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: April 11, 2001
    Publication date: March 28, 2002
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • .beta.-polypeptide foldamers of well-defined secondary structure
    Patent number: 6060585
    Abstract: Disclosed are .beta.-peptides containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the .alpha. and .beta. carbons of the peptide backbone. The .beta.-peptides adopt stable helical and sheet structures in both the solid state and in solution. Method of generating combinatorial libraries of peptides containing .beta.-peptide residues and the libraries formed thereby are disclosed.
    Type: Grant
    Filed: March 4, 1998
    Date of Patent: May 9, 2000
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Daniel H. Appella, Laurie A. Christianson, Daniel A. Klein, Susanne Krauthauser, Yong Jun Chung, Xifang Wang