Abstract: The invention provides a Probiotic microcapsule and a preparation method thereof, relating to the technical field of Probiotic products. The method includes the following steps: (a) preparing a capsule core containing Probiotics: mixing the capsule core materials including Probiotic powder, microcrystalline cellulose and starch, then adding a hydroxypropyl methylcellulose solution thereinto, while mixing evenly, making the obtained mixture materials into spherical particulate capsule cores by the extrusion spherization method; (b) coating by atomization: coating the microcapsule cores with a coating material solution in a single layer or multiple layers by atomization, getting core-shell microcapsules. The Probiotic microcapsules prepared by the present invention have a large encapsulation, uniform microcapsule particles, controllable particle size, storage-resistance, targetability to intestinal tracts, resistance to gastric acids and high temperature stability.

Abstract: A method of acquiring feature information of a detected object is provided, including: controlling the detected object to pass through a detection apparatus; controlling an imaging system to perform radiation scanning on the detected object acquiring a radiation scanning image of the detected object acquiring feature information of the detected object through the radiation scanning image. The detected object includes a first part, a detection part and a second part sequentially in a first direction. The acquiring feature information of the detected object through the radiation scanning image includes: acquiring a first boundary line between the detection part and the first part and a second boundary line between the detection part and the second part through the radiation scanning image; and calculating a dimension between the first boundary line and the second boundary line in the first direction to acquire a dimension of the detection part in the first direction.

Abstract: In a fault image generation method, a processing device obtains a non-fault image and a first fault image, where the non-fault image records a first object that is not faulty, the first fault image records a second object that is faulty, and a type of the first object is different from a type of the second object. The processing device then migrates a fault pattern of the second object in the first fault image to the first object in the non-fault image, to obtain a second fault image, where the second fault image presents the first object in a faulty state.

Abstract: A camera module compensating for loss of focus caused by heat-deformation of a lens assembly above a photosensitive element includes the lens assembly, the photosensitive element, a circuit board, and a focusing assembly. The photosensitive element receives light through the lens assembly. The focusing assembly is arranged to apply deformation when temperature changes by moving the photosensitive element away from or toward the lens assembly, so correcting a focal length of the lens assembly on the photosensitive element. An electronic device is also disclosed.

Abstract: Disclosed are a new AXL-targeting monoclonal antibody and antibody-drug conjugate. Also disclosed is a method for preparing said antibody and antibody-drug conjugate. The AXL antibody of the present invention can bind with purified human AXL protein and multiple AXL on tumor cell surface with high effectiveness and high specificity. Said humanized antibody also has high affinity and low immunogenicity. Said AXL antibody-drug conjugate has markable performance against tumors having high AXL expression.

Abstract: A bubble detection device and a sample processing instrument are provided. The bubble detection device includes a body, a cover and a detection circuit board. The body includes a bottom wall and first and second side walls respectively extending from two sides of the bottom wall. The bottom, first and second side walls define a groove for accommodating a sample pipe of a sample processing instrument, and first and second holes are respectively provided in the first and second side walls to allow light from a light source to pass through the sample pipe. The cover includes a top portion for covering the groove and first and second side portions attached to the body. The detection circuit board includes the light source and a photoelectric sensor and is attached to the body such that they are aligned with the first and second holes respectively to sense intensity of the light passing through the sample pipe. The sample processing instrument includes the bubble detection device.

Abstract: A weeding device for crops having a seedling avoidance function includes a rack connected to a weeding machine. A hydraulic pump and two hydraulic cylinders are mounted to the rack. Bottom ends of each of the two hydraulic cylinders are provided with a vertically arranged support rod. An inter-row weeder is mounted to a bottom end of each of the two support rods. A slider configured to reciprocate in a horizontal direction is positioned on two slide rails that are mounted to the rack. An inter-plant weeder is mounted to a bottom side of the slider. A plurality of weeder blades are arranged side by side on the inter-plant weeder. At the weeding position, an arrangement direction of weeder blades is perpendicular to an advancing direction, and at the weed avoidance position, the arrangement direction of the weeder blades is parallel to the advancing direction, thereby avoiding crops.

Abstract: A method for constructing a multiplex PCR library for high-throughput targeted sequencing: first acquiring a targeted DNA product by means of a high-specificity multiplex PCR reaction, and then digesting with a specific endonuclease, such that a specific molecular barcode is produced at the tail end of the PCR product; thus, the library construction process is more efficient, and the accuracy and sequencing depth of the obtained data are also ensured.

Abstract: A sealing composition for use in unit dose packages is provided, including: 70 to 98 wt % water; 1 to 30 wt % of a hydrogen bonding component; and 1 to 30 wt % of a complex forming component.

Abstract: Described is a free DNA-based disease prediction model and a construction method therefor and an application thereof. The construction method includes the steps of: 1) obtaining sequencing data of free DNA samples of diseased individuals and control individuals, the number of the diseased individuals and the number of the control individuals being both multiple; 2) selecting, according to the coverage of the sequencing data of the free DNA samples of the diseased individuals and the control individuals on a genome, a gene set having a difference in the coverage of a transcription initiation site region between the diseased individuals and the control individuals; and 3) for genes in the gene set, using the coverage of the sequencing data on the gene transcription initiation site region as an input prediction model for training so as to establishing a disease prediction model.

Abstract: A multi-channel static CT device is provided, and the multi-channel static CT device includes: a scanning channel including a plurality of scanning sub-channels; a distributed X-ray source including a plurality of ray emission points arranged around the scanning channel; and a detector module including a plurality of detectors arranged around the scanning channel, wherein the plurality of detectors are arranged corresponding to the plurality of ray emission points.

Abstract: Provided is speaker, including magnetic circuit unit, frame fixed to the magnetic circuit unit, and first and second sound-producing unit both fixed to the frame. The magnetic circuit unit includes magnetically conductive assembly with lower clamping plate and magnet component located on lower clamping plate. A third magnetic conductor is arranged around the magnet component, first magnetic conductor, and second magnetic conductor. A first and a second voice coil are respectively located in magnetic gaps between third magnetic conductor and second magnetic conductor and between third magnetic conductor and first magnetic conductor. The two sound-producing units share the magnetic circuit unit.

Abstract: An electrode assembly, where an outer surface of the electrode assembly includes a first surface, a first end face, a second surface, and a second end face that are connected in sequence, the first surface is provided opposite to the second surface, and the first end face is provided opposite to the second end face; a first adhesive layer, where the first adhesive layer is adhered to the first end face and extends from the first end face to the first surface and the second surface separately, and a side of the first surface provided with the first adhesive layer is defined as a top side; and a second adhesive layer, where the second adhesive layer is adhered to the second end face and extends from the second end face to the first surface and the second surface separately.

Abstract: The present invention relates to the field of biotechnology. A method and system of detecting fetal chromosomal abnormalities are disclosed.

Abstract: A method for generating a video intermediate frame, including obtaining a target video frame pair; constructing an image pyramid for each video frame in the target video frame pair; and generating an intermediate frame of the target video frame pair by using a bidirectional optical flow estimation model and a pixel synthesis model in a layer-by-layer recursive calling manner according to an order of the image pyramid from a high layer to a low layer based on the image pyramid, wherein the generating of the intermediate frame of the target video frame pair comprising: repairing a bidirectional optical flow corresponding to a previous layer using the bidirectional optical flow estimation model, and repairing a previous intermediate frame corresponding to the previous layer using the pixel synthesis model.

Abstract: Disclosed is a nitrogen-containing heterocyclic compound, a method for preparing the same and a use of the same. The present disclosure provides a nitrogen-containing heterocyclic compound of formula I, a pharmaceutically acceptable salt thereof, a stereoisomer thereof, a tautomer thereof or an isotopically labeled compound thereof, and the nitrogen-containing heterocyclic compound is expected to treat and/or prevent various RAS-related diseases.

Abstract: Provided is a method for constructing a prediction model used for predicting a pregnancy status of a pregnant woman. The method includes: step 1 of constructing a training set and an optional test set, the training set and the optional test set each consisting of a plurality of pregnant woman samples, the pregnant woman samples each having a known pregnancy status; step 2 of determining, for each pregnant woman sample in the training set, a predetermined parameter of the pregnant woman sample, the predetermined parameter including differentially expressed gene information of the pregnant woman sample, the differentially expressed gene information being obtained through calculation based on sequencing information of fetal cell-free nucleic acids in peripheral blood of the pregnant woman sample; and step 3 of constructing the prediction model based on the known pregnancy status and the predetermined parameter.

Abstract: A page layout method includes obtaining page information, element information of at least one page element to be laid out, and a layout rule; obtaining at least one candidate page layout policy based on the page information, the element information, and the layout rule using a reinforcement learning algorithm; and determining a target page layout policy from the at least one candidate page layout policy using an imitation learning algorithm.

Abstract: Nucleic acid sequencing methods and systems, the systems including nanochannel chip including: a nanochannel formed in an upper surface of the nanochannel chip and; a roof covering the nanochannel and comprising nanopores and a field enhancement structure; and a barrier disposed in the nanochannel. The method including: introducing a buffer solution including long-chain nucleic acids to the nanochannel chip; applying a voltage potential across the nanochannel chip to drive the nucleic acids through the nanochannel, towards the barrier, and to translocate the nucleic acids through nanopores adjacent to the barrier, such that bases of each of the nucleic acids pass through the field enhancement structure one base at a time and emerge onto an upper surface of the roof; detecting the Raman spectra of the bases of the nucleic acids as each base passes through the electromagnetic-field enhancement structure; and sequencing the nucleic acids based on the detected Raman spectra.