Patents by Inventor Xin Linghu

Xin Linghu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240147164
    Abstract: The present disclosure provides a multifunctional sounding device, which includes a housing body with a containment space, and a sounding unit. The housing body is provided with a sound outlet. The sounding unit includes a frame, a vibration system, and a magnetic circuit system. The multifunctional sounding device also includes a motor assembly accommodated in the containment space. The motor assembly includes a vibration unit having a driving coil. The driving coil is positioned on the side of the first auxiliary magnetic circuit away from the vibration system. The main magnetic circuit and the second auxiliary magnetic circuit are fixed to the vibration unit. The first auxiliary magnetic circuit is fixed to the housing body. Compared with related technologies, the multifunctional sounding device in the present disclosure has a small overall thickness and volume, and has excellent acoustic performance.
    Type: Application
    Filed: June 27, 2023
    Publication date: May 2, 2024
    Inventors: Xin Jin, Fan Zhang, Ronglin Linghu, Wei Song
  • Publication number: 20240147158
    Abstract: The present disclosure provides a multifunctional sounding device, which includes a lower housing, an upper housing and a sounding unit. The sounding unit includes a frame, a vibration system and a magnetic circuit system. The magnetic circuit system includes a main magnetic circuit, a first auxiliary magnetic circuit and a second auxiliary magnetic circuit. The first auxiliary magnetic circuit includes a first auxiliary magnet and a first auxiliary pole plate. The first auxiliary pole plate fixes the first auxiliary magnet to the upper housing. The multifunctional sounding device also includes a motor assembly, and the motor assembly includes a vibration unit and an elastic member. The multifunctional sounding device of the present disclosure not only simplifies the fixing method of the magnetic circuit system, but also reduces the dimensional accuracy requirements of the magnetic circuit system, meeting the needs of mass production.
    Type: Application
    Filed: June 26, 2023
    Publication date: May 2, 2024
    Inventors: Xin Jin, Fan Zhang, Wei Song, Ronglin Linghu
  • Publication number: 20240147157
    Abstract: The present disclosure provides a multifunctional sounding device, which includes a lower housing, an upper housing and a sounding unit. The sounding unit includes a frame, a vibration system and a magnetic circuit system. The magnetic circuit system includes a main magnetic circuit, a first auxiliary magnetic circuit and a second auxiliary magnetic circuit. The first auxiliary magnetic circuit includes a first auxiliary magnet and a first auxiliary pole plate. The multifunctional sounding device also includes a motor assembly having a vibration unit and an elastic member. The main magnetic circuit, the first auxiliary magnetic circuit and the second auxiliary magnetic circuit are respectively fixed in the lower housing or the upper housing. This is not only beneficial to control the magnetic gap, but also improves production accuracy and product consistency.
    Type: Application
    Filed: June 26, 2023
    Publication date: May 2, 2024
    Inventors: Xin Jin, Fan Zhang, Wei Song, Ronglin Linghu
  • Publication number: 20240147165
    Abstract: The present disclosure provides a multifunctional sounding device, including a housing body with a containment space and a sounding unit accommodated in the containment space. The sounding unit includes a frame, a vibration system, and a magnetic circuit system. The sounding device further includes a motor assembly accommodated in the containment space, having a vibration unit with a voice coil disposed on a side of the magnetic circuit system away from the vibration system, and an elastic member suspending the vibration unit in the containment space. The overall thickness of the multifunctional sounding device of the present disclosure is small, the volume is small, and the acoustic performance is excellent; this structure also reduces the cost of parts and assembly costs, making the multifunctional sounding device widely used.
    Type: Application
    Filed: June 26, 2023
    Publication date: May 2, 2024
    Inventors: Xin Jin, Fan Zhang, Ronglin Linghu, Wei Song
  • Publication number: 20240034739
    Abstract: Processes are provided herein for the preparation of a bicyclic ketone compound of formula (I), or a stereoisomer thereof: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and n are as defined herein; and compounds prepared by these processes.
    Type: Application
    Filed: October 2, 2023
    Publication date: February 1, 2024
    Applicants: Genentech, Inc., Hoffmann-La Roche Inc.
    Inventors: Allen Yu HONG, Nicholas WONG, Sean M. KELLY, Lauren Elizabeth SIROIS, Sara SCHWEGLER, Xin LINGHU, Francis GOSSELIN, Katarzyna Aleksandra PIECHOWICZ, Carmela MOLINARO, Dennis WETZL
  • Publication number: 20230303556
    Abstract: Provided herein are compounds of Formula (I): or a pharmaceutically acceptable salt thereof. The provided compounds are useful Poly ADP-ribose glycohydrolase (PARG) inhibitors. Additional utilities and advantages are described herein.
    Type: Application
    Filed: March 22, 2023
    Publication date: September 28, 2023
    Inventors: Paul A. BARSANTI, Michael Patrick DILLON, Firoz Ali JAIPURI, Ying-Zi XU, Xin LINGHU, Monah ABED
  • Patent number: 11702452
    Abstract: Methods for making an arylomycin ring of formula t or salts or solvates thereof, wherein R, R1, R2, R3, R4, R5, R6, R7, R8, R9, R5, R10 and Pg1 are as defined herein.
    Type: Grant
    Filed: November 2, 2021
    Date of Patent: July 18, 2023
    Assignee: Genentech, Inc.
    Inventors: Filip Petronijevic, Ngiap-Kie Lim, Nicholas Wong, Allen Hong, Haiyun Hou, Xin Linghu, Francis Gosselin
  • Publication number: 20220056078
    Abstract: Methods for making an arylomycin ring of formula t or salts or solvates thereof, wherein R, R1, R2, R3, R4, R5, R6, R7, R8, R9, R5, R10 and Pg1 are as defined herein.
    Type: Application
    Filed: November 2, 2021
    Publication date: February 24, 2022
    Applicant: Genentech, Inc.
    Inventors: Filip PETRONIJEVIC, Ngiap-Kie LIM, Nicholas WONG, Allen HONG, Haiyun HOU, Xin LINGHU, Francis GOSSELIN
  • Patent number: 11192924
    Abstract: Methods for making an arylomycin ring of formula t or salts or solvates thereof, wherein R, R1, R2, R3, R4, R5, R6, R7, R8, R9, R5, R10 and Pg1 are as defined herein.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: December 7, 2021
    Assignee: Genentech, Inc.
    Inventors: Filip Petronijevic, Ngiap-Kie Lim, Nicholas Wong, Allen Hong, Haiyun Hou, Xin Linghu, Francis Gosselin
  • Patent number: 11098028
    Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: August 24, 2021
    Assignee: Genentech, Inc.
    Inventors: Jinguang Lin, Alexandra Chestakova, Wei Gu, Hans Iding, Jing Li, Xin Linghu, Patrik Meier, Chunbo Sha, Jeffrey Stults, Youchu Wang, Haiming Zhang, Jianqian Zhang, Tao Zhang
  • Patent number: 11066389
    Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: July 20, 2021
    Assignee: Genentech, Inc.
    Inventors: Jinguang Lin, Alexandra Chestakova, Wei Gu, Hans Iding, Jing Li, Xin Linghu, Patrik Meier, Chunbo Sha, Jeffrey Stults, Youchu Wang, Haiming Zhang, Jianqian Zhang, Tao Zhang
  • Publication number: 20200255476
    Abstract: Methods for making an arylomycin ring of formula t or salts or solvates thereof, wherein R, R1, R2, R3, R4, R5, R6, R7, R8, R9, R5, R10 and Pg1 are as defined herein.
    Type: Application
    Filed: September 24, 2019
    Publication date: August 13, 2020
    Applicant: Genentech, Inc.
    Inventors: Filip PETRONIJEVIC, Ngiap-Kie LIM, Nicholas WONG, Allen HONG, Haiyun HOU, Xin LINGHU, Francis GOSSELIN
  • Patent number: 10689325
    Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 23, 2020
    Assignee: Genentech, Inc.
    Inventors: Stephan Bachmann, Serena Maria Fantasia, Michael Jansen, Stefan Koenig, Xin Linghu, Sebastian Rieth, Nathaniel L. Segraves, Andreas Zogg
  • Publication number: 20200190061
    Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid
    Type: Application
    Filed: December 18, 2019
    Publication date: June 18, 2020
    Applicant: Genentech, Inc.
    Inventors: JINGUANG LIN, ALEXANDRA CHESTAKOVA, WEI GU, HANS IDING, JING LI, XIN LINGHU, PATRIK MEIER, CHUNBO SHA, JEFFREY STULTS, YOUCHU WANG, HAIMING ZHANG, JIANQIAN ZHANG, TAO ZHANG
  • Patent number: 10611753
    Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: April 7, 2020
    Assignee: Genentech, Inc.
    Inventors: Jinguang Lin, Alexandra Chestakova, Wei Gu, Hans Iding, Jing Li, Xin Linghu, Patrik Meier, Chunbo Sha, Jeffrey Stults, Youchu Wang, Haiming Zhang, Jianqian Zhang, Tao Zhang
  • Publication number: 20190367484
    Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid
    Type: Application
    Filed: August 8, 2019
    Publication date: December 5, 2019
    Applicant: Genentech, Inc.
    Inventors: JINGUANG LIN, ALEXANDRA CHESTAKOVA, WEI GU, HANS IDING, JING LI, XIN LINGHU, PATRIK MEIER, CHUNBO SHA, JEFFREY STULTS, YOUCHU WANG, HAIMING ZHANG, JIANQIAN ZHANG, TAO ZHANG
  • Publication number: 20190270695
    Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.
    Type: Application
    Filed: May 17, 2019
    Publication date: September 5, 2019
    Applicant: Genentech, Inc.
    Inventors: Stephan Bachmann, Serena Maria Fantasia, Michael Jansen, Stefan Koenig, Xin Linghu, Sebastian Rieth, Nathaniel L. Segraves, Andreas Zogg
  • Patent number: 10336683
    Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: July 2, 2019
    Assignee: Genentech, Inc.
    Inventors: Stephan Bachmann, Serena Maria Fantasia, Michael Jansen, Stefan Koenig, Xin Linghu, Sebastian Rieth, Nathaniel L. Segraves, Andreas Zogg
  • Publication number: 20180134685
    Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid
    Type: Application
    Filed: January 10, 2018
    Publication date: May 17, 2018
    Applicant: Genentech, Inc.
    Inventors: Jinguang Lin, Alexandra Chestakova, Wei Gu, Hans Iding, Jing Li, Xin Linghu, Patrik Meier, Chunbo Sha, Jeffrey Stults, Youchu Wang, Haiming Zhang, Jianqian Zhang, Tao Zhang
  • Publication number: 20170252457
    Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.
    Type: Application
    Filed: March 3, 2017
    Publication date: September 7, 2017
    Applicant: Genentech, Inc.
    Inventors: Stephan Bachmann, Serena Maria Fantasia, Michael Jansen, Stefan Koenig, Xin Linghu, Sebastian Rieth, Nathaniel L. Segraves, Andreas Zogg