Abstract: The present invention discloses a stereo garage that comprises: a main body provided with a lifting shaft, wherein the lifting shaft is provided with an opening; a lifting platform located in the lifting shaft, wherein the lifting platform can ascend or descend in the lifting shaft along a height direction of the main body, such that the lifting platform can switch between an initial position and an end position, wherein the lifting platform can close the opening when the lifting platform is located in the initial position; an anti-falling device connected to the main body, wherein the anti-falling device comprises a blocking rod which can be switched between a locking position and an unlocking position; wherein, the blocking rod can block a movement of a vehicle when the blocking rod is located in the locking position, and the lifting platform can cause the blocking rod to be switched from the locking position to the unlocking position when the lifting platform comes into the initial position.

Abstract: This application relates to the artificial intelligence field, and discloses a neural network search method and a related apparatus. The neural network search method includes: constructing attention heads in transformer layers by sampling a plurality of candidate operators during model search, to construct a plurality of candidate neural networks, and comparing performance of the plurality of candidate neural networks to select a target neural network with higher performance. In this application, a transformer model is constructed with reference to model search, so that a new attention structure with better performance than an original self-attention mechanism can be generated, and effect in a wide range of downstream tasks is significantly improved.

Abstract: A compound, as represented by formula I, as a TLR7 agonist, a method for preparing the compound, and the use of the compound in treating diseases mediated by the TLR7 agonist are provided. Studies on the activity of a human-derived receptor, a TLR7 agonist, show that compounds have a strong agonistic effect on the human-derived receptor, TLR7, and can be used as a foreground compound for treating diseases mediated by the TLR7 agonist.

Abstract: The present invention relates to a carbide tool cleaning and coating production line and a method, including a cleaning device including a support frame, a cleaning mechanism and a drying mechanism are sequentially disposed under the support frame connected to a moving mechanism, the moving mechanism is connected to a lifting mechanism being capable of being connected to a tool fixture bracket being configured to accommodate the tool fixture; a coating device including a coating chamber which a plane target mechanism and a turntable assembly disposed in, the turntable assembly is capable of being connected to a plurality of tool fixtures being capable of rotating around an axial line of the coating chamber under the driving of the turntable assembly and rotating around an axial line thereof at the same time; and, a manipulator being disposed between the cleaning device and the coating device.

Abstract: Disclosed herein are high Tm RNA nanostructures that can be composed of one or more modules or motifs to build RNA nanostructures with or without layers. The RNA nanostructures can have a core domain and three or more double-stranded arms and formulations thereof to conjugate high copy numbers of therapeutics, pH responsive or enzyme cleavable drug cargo. Also described herein is a design strategy for generation of synthetic RNA oligonucleotides that can self assemble into highly thermostable RNA structures. Also described herein are uses of the RNA nanostructures described herein.

Abstract: A battery and an electrical device are provided. The battery includes at least one first battery cell and at least one second battery cell, an internal resistance of the first battery cell is greater than that of the second battery cell, and a heat transfer rate of the first battery cell is less than that of the second battery cell.

Abstract: A computer-implemented method is provided for model training performed by a processing system. The method comprises determining a set of first weights based on a first matrix associated with a source model, determining a set of second weights based on the set of first weights, forming a second matrix associated with a target model based on the set of first weights and the set of second weights, initializing the target model based on the second matrix, and training the target model.

Abstract: A compound having a structure as shown in general formula (I), a deuterated compound, a stereoisomer, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising same, and use thereof. The compound has a good PIM kinase inhibitory effect, is a novel and ideal PIM inhibitor having high activity and low toxicity, and can be used for treating and/or preventing hematoma such as acute myeloid leukemia, bone marrow fibrosis and chronic lymphocytic leukemia, solid tumors such as gastric cancer and prostate cancer, and other diseases.

Abstract: Described is a method of identifying a short-circuit (SC) like event in a circuit breaker (CB). The method comprises sampling an incoming current to the CB to determine a maximum value of a slope of a curve of the incoming current. The method includes sampling the incoming current again before a level of the incoming current reaches a predetermined, preset, selected, or calculated SC threshold value THSC for the CB. The method involves determining from the sampled incoming current that a value of the slope of the incoming current has changed from its maximum slope value to a lower slope value to thereby determine that the incoming current is indicative of a SC like event and does not comprise a real SC event.

Abstract: The present application relates to a current collector, an electrode plate, a battery cell, a battery, and an electric device. The current collector includes a stainless steel current-collecting portion for collecting a current, where the stainless steel current-collecting portion includes a blank area and a coating area that are arranged adjacent to each other in a preset direction, the coating area is configured to be coated with an active material, and the blank area has a hardness less than that of the coating area.

Abstract: A multi-procedure integrated automatic production line for hard alloy blades under robot control is provided. The production line includes a rail-guided robot. A cutter passivation device and a blade cleaning and drying device are arranged on one side of the rail-guided robot. A blade-coating transfer table, a blade coating device, a blade boxing transfer table, a blade-tooling dismounting device and a blade boxing device are sequentially arranged on another side of the rail-guided robot. The blade-tooling dismounting device is arranged on one side of the blade boxing transfer table. The production line further includes squirrel-cage toolings for carrying the blades. The squirrel-cage tooling that are loaded with the blades can run among the cutter passivation device, the blade cleaning and drying device, the blade-coating transfer table and the blade boxing transfer table. The blades after being treated through the blade-tooling dismounting device are sent to the blade boxing device.

Abstract: A plasma processing chamber for depositing a film on an underside surface of a wafer, includes showerhead pedestal. The showerhead pedestal includes a first zone and a second zone. An upper separator fin is disposed over a top surface of the showerhead pedestal and a lower separator fin is disposed under the top surface of the showerhead pedestal and aligned with the upper separator fin. The first zone is configured for depositing a first film to the underside surface of the wafer and the second zone is configured for depositing a second film to the underside surface of the wafer. In another embodiment, a top surface of the showerhead pedestal may be configured to receive a masking plate instead of the upper separator fin. The masking plate is configured with a first area that has openings and a second area that is masked. The first areas is used to provide the process gas to a portion of the underside surface of the wafer for depositing a film.

Abstract: The audio playing method is provided by embodiments of the present disclosure, applied to on-board audio system (including multiple speaker modules arranged at different positions in a car cabin, the audio playing method includes: obtaining an audio signal to be played; decomposing the audio signal to obtain multiple audio source signals of different categories, where each of the multiple sound source signals includes multiple sub sound source signals of a same category; establishing a route between all sub sound source signals and the multiple speaker modules according to a preset distribution principle indicating rules for playing different sub sound source signals by different speaker modules; and playing each of the multiple sub sound source signals by a corresponding speaker module according to the route. The present disclosure provides more accurate and immersive car multi-channel surround sound playback, which can effectively improve overall acoustic experience of the on-board audio system.

Abstract: Provided are methods and compositions from reprogramming human glial cells into human neurons. The reprogramming is achieved using combinations of compounds that can modify signaling via Transforming growth factor beta (TGF-?), Bone morphogenetic protein (BMP), glycogen synthase kinase 3 (GSK-3), and ?-secretase/Notch pathways. The reprogramming is demonstrated using groups of three or four compounds that are chosen from the group thiazovivin, LDN193189, SB431542, TTNPB, CHIR99021, DAPT, VPA, SAG, purmorphamine. Reprogramming is demonstrated using the group of LDN193189/CHIR99021/DAPT, the group of B431542/CHIR99021/DAPT, the group of LDN193189/DAPT/SB431542, the group of LDN193189/CHIR99021/SB431542, a three drug combination of SB431542/CHIR99021/DAPT. Reprogramming using functional analogs of the compounds is also provided, as are pharmaceutical formulations that contain the drug combinations.

Abstract: A surface cleaning apparatus includes a housing including an upright handle assembly and a base mounted to the upright handle assembly. The surface cleaning apparatus is further provided with a brushroll and a fluid delivery system comprising a fluid supply chamber and a fluid dispenser configured to dispense fluid to the brushroll.

Abstract: The present invention relates to T cell receptors (TCR) against cancer/testis antigens NY-ESO-1 and CT83 presented by multiple HLA molecules. The preferred TCRs of the invention deriving from human T cells demonstrates high affinity and antigen specificity in vitro and in vivo. The present invention also relates to the modulation of TCR-T CAR-T cell signaling and functional persistence in cancer immunotherapy.

Abstract: A method includes performing a plasma activation on a surface of a first package component, removing oxide regions from surfaces of metal pads of the first package component, and performing a pre-bonding to bond the first package component to a second package component.

Abstract: A method for obstacle avoidance in degraded environments of robots based on intrinsic plasticity of an SNN is disclosed. A decision network in a synaptic autonomous learning module takes lidar data, distance from a target point and velocity at a previous moment as state input, and outputs the velocity of left and right wheels of the robot through the autonomous adjustment of the dynamic energy-time threshold, so as to carry out autonomous perception and decision making. The method solves the difficulty of the lack of intrinsic plasticity in the SNN, which leads to the difficulty of adapting to degraded environments due to the homeostasis imbalance of the model, is successfully deployed in mobile robots to maintain a stable trigger rate for autonomous navigation and obstacle avoidance in degraded, disturbed and noisy environments, and has validity and applicability on different degraded scenes.

Abstract: A bio-sample homogenizer with a direct drive motor generating reciprocal motion for sample disruption, following continuous rotation for centrifuge tissue sample dissociation for debris separation. The homogenizer device comprises: a motor, a plurality of sample containers, a frame work to mount the sample containers. The direct drive motor generates constant acceleration/deceleration to drive the platform for producing a horizon reciprocal motion. A plurality of holding slots mounted on the framework for holding the plurality of sample containers containing with beads and tissue sample. The beads in the sample containers cause a blending action on the tissue sample for fully dissociation of the sample. Following continuous rotation generating centrifuge force, the finely dissociated solution is separated from the debris.

Abstract: A plasma processing chamber for depositing a film on an underside surface of a wafer, includes showerhead pedestal. The showerhead pedestal includes a first zone and a second zone. An upper separator fin is disposed over a top surface of the showerhead pedestal and a lower separator fin is disposed under the top surface of the showerhead pedestal and aligned with the upper separator fin. The first zone is configured for depositing a first film to the underside surface of the wafer and the second zone is configured for depositing a second film to the underside surface of the wafer. In another embodiment, a top surface of the showerhead pedestal may be configured to receive a masking plate instead of the upper separator fin. The masking plate is configured with a first area that has openings and a second area that is masked. The first areas is used to provide the process gas to a portion of the underside surface of the wafer for depositing a film.