Patents by Inventor Xingdong ZHANG

Xingdong ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240131222
    Abstract: The present invention relates to a transdermal photocuring forming hydrogel with biological activity. The hydrogel can release recombinant collagen with biological activity, the recombinant collagen includes a sequence as shown in SEQ ID No. 1, an amino acid sequence of the recombinant collagen includes N basic repetitive units, and each basic repetitive unit includes n1 of the following characteristic amino acid sequences: “G-Xaa1-Xaa2-G-E-Xaa3”; the 3? end and the 5? end of the basic repetitive unit are connected to form the above characteristic amino acid sequence. The recombinant collagen provided by the present invention has relatively obvious integrin binding activity, and has the effects of promoting cell adhesion, proliferation and differentiation. The hydrogel of the present invention has good biocompatibility and stable quality, which can be cured and formed in situ in a transdermal photo-crosslinking manner after injection, with simple, convenient and controllable operation.
    Type: Application
    Filed: October 8, 2023
    Publication date: April 25, 2024
    Inventors: Hai LIN, He QIU, Jing WANG, Jian WANG, Yang XU, Lu SONG, Xia YANG, Xingdong ZHANG
  • Publication number: 20240115763
    Abstract: The present invention discloses a recombinant collagen protein and its use in the cartilage repair matrix. The present invention discloses a recombinant collagen protein which contains the sequence shown in SEQ ID No. 1; the amino acid sequence of the stated recombinant collagen protein comprises N basic repetitive units; the basic repetitive unit contains n1 amino acid sequences with the following characteristic: G-Xaa1-Xaa2-G-E-Xaa3; the 3? end and the 5? end of the basic repetitive unit are connected to form the amino acid sequence with the above characteristic. The recombinant collagen protein claimed by the present invention has significant integrin binding activity, has the effect of promoting cell adhesion, proliferation, differentiation, and repairing cartilage tissue defects, etc, and it has promising prospects for application.
    Type: Application
    Filed: October 9, 2023
    Publication date: April 11, 2024
    Inventors: Hai LIN, Yang XU, Jing WANG, Zhanhong LIU, Xia YANG, Xingdong ZHANG
  • Publication number: 20240093472
    Abstract: Disclosed is a water tank drainage volume control structure comprising: a water tank body (1), having a first water storage chamber (11) and a second water storage chamber (12), the first water storage chamber (11) being provided with a first drainage channel, and the second water storage chamber (12) being provided with a second drainage channel; a drainage valve (2), used for controlling the opening/closing of the second drainage channel, the drainage valve (2) being provided with a full-drainage switch and a half-drainage switch for controlling the opening of the second drainage channel; and a water blocking member (3), moving with respect to the water tank body (1) under the control of the full-drainage switch or the half-drainage switch so as to control switching of the first drainage channel between open and closed states. The present invention uses a drainage valve to control drainage, can also achieve half drainage and full drainage of a water tank, and is simple in structure and reliable in function.
    Type: Application
    Filed: January 7, 2021
    Publication date: March 21, 2024
    Inventors: Rongyu ZHANG, Xingdong WANG
  • Patent number: 11844880
    Abstract: A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: December 19, 2023
    Assignees: Sichuan University, Shanxi Jinbo Bio-Pharmaceutical Co., Ltd
    Inventors: Yunbing Wang, Li Yang, Rifang Luo, Lu Lu, Xia Yang, Xingdong Zhang
  • Publication number: 20210369923
    Abstract: A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.
    Type: Application
    Filed: May 26, 2021
    Publication date: December 2, 2021
    Applicants: Sichuan University, Shanxi Jinbo Bio-Pharmaceutical Co., Ltd
    Inventors: Yunbing WANG, Li YANG, Rifang LUO, Lu LU, Xia YANG, Xingdong ZHANG
  • Publication number: 20210322641
    Abstract: An anti-thrombotic and endothelialization-enhanced bioprosthetic valve material and preparation thereof are provided. The preparation method includes the following steps: immersing a glutaraldehyde cross-linked bioprosthetic valve material in functional reagent solution for 1-24 h, adjusting pH value of the solution to 3-8, removing it from solution and cleaning with deionized water. The new valve material of the present invention can effectively reduce the toxicity and side effects of the existing glutaraldehyde cross-linked bioprosthetic valve material and effectively reduce thrombosis, along with enhanced endothelialization. The material prepared can be used for pulmonary valve, aortic valve, mitral valve, tricuspid valve, venous valve and other cardiovascular implantable medical devices.
    Type: Application
    Filed: April 21, 2021
    Publication date: October 21, 2021
    Applicant: Sichuan University
    Inventors: Li YANG, Yunbing WANG, Rifang LUO, Xingdong ZHANG
  • Patent number: 10770251
    Abstract: An alternating current contactor comprises a base and a magnetic yoke. The magnetic yoke is mounted on a bottom plate of the base. A magnetic yoke support for supporting and buffering the magnetic yoke is respectively provided at two sides of the magnetic yoke, wherein sidewalls at two sides of each magnetic yoke support, which are connected with the magnetic yoke are different in thickness. The magnetic yoke support of the alternating current contactor of the utility model has a simple structure due to the arrangement of an asymmetric eccentric structure. The up-down position of the magnetic yoke relative to the bottom plate of the base can be adjusted by changing an assembly direction of the magnetic yoke supports, thereby achieving the purpose of adjusting the total stroke of the product with high flexibility.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: September 8, 2020
    Assignee: ZHEJIANG CHINT ELECTRICS CO., LTD.
    Inventors: Ping Xu, Yujia Hu, Xingdong Zhang, Zhiwen Zhang, Tifeng Xiao
  • Publication number: 20180350543
    Abstract: An alternating current contactor comprises a base and a magnetic yoke. The magnetic yoke is mounted on a bottom plate of the base. A magnetic yoke support for supporting and buffering the magnetic yoke is respectively provided at two sides of the magnetic yoke, wherein sidewalls at two sides of each magnetic yoke support, which are connected with the magnetic yoke are different in thickness. The magnetic yoke support of the alternating current contactor of the utility model has a simple structure due to the arrangement of an asymmetric eccentric structure. The up-down position of the magnetic yoke relative to the bottom plate of the base can be adjusted by changing an assembly direction of the magnetic yoke supports, thereby achieving the purpose of adjusting the total stroke of the product with high flexibility.
    Type: Application
    Filed: October 24, 2016
    Publication date: December 6, 2018
    Applicant: ZHEJIANG CHINT ELECTRICS CO., LTD.
    Inventors: Ping XU, Yujia HU, Xingdong ZHANG, Zhiwen ZHANG, Tifeng XIAO
  • Patent number: 9681494
    Abstract: The present invention provides a split-type mobile terminal which includes a host and at least one sub-device connected to the host. Wherein, the host includes: a state obtaining unit (102A) configured to obtain a real-time state of the host when a communications event occurs in the host; a state determining unit (102B) configured to determine whether or not the real-time state is a preset interactive state; a data interacting unit (102C) configured to send a response command to at least one of the at least one sub-device if the determining result is yes; and a host processing unit (102D) configured to directly respond to the communications event if the determining result is no. Each sub-device includes a sub-device processing unit (1040) configured to respond to the communications event according to the received respond command. The present invention further provides an interaction processing method for a communications event.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: June 13, 2017
    Assignees: YULONG COMPUTER TELECOMMUNICATION SCIENTIFIC (SHENZHEN) CO., LTD., DONGGUAN YULONG TELECOMMUNICATION TECH CO., LTD.
    Inventors: Peng Song, Bin Guo, Xingdong Zhang
  • Publication number: 20160081138
    Abstract: The present invention provides a split-type mobile terminal which includes a host and at least one sub-device connected to the host. Wherein, the host includes: a state obtaining unit (102A) configured to obtain a real-time state of the host when a communications event occurs in the host; a state determining unit (102B) configured to determine whether or not the real-time state is a preset interactive state; a data interacting unit (102C) configured to send a response command to at least one of the at least one sub-device if the determining result is yes; and a host processing unit (102D) configured to directly respond to the communications event if the determining result is no. Each sub-device includes a sub-device processing unit (1040) configured to respond to the communications event according to the received respond command. The present invention further provides an interaction processing method for a communications event.
    Type: Application
    Filed: April 26, 2013
    Publication date: March 17, 2016
    Applicants: YULONG COMPUTER TELECOMMUNICATION SCIENTIFIC (SHENZHEN) CO., LTD., DONGGUAN YULONG TELECOMMUNICATION TECH CO., LTD.
    Inventors: Peng SONG, Bin GUO, Xingdong ZHANG