Patents by Inventor Xingdong ZHANG
Xingdong ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240131222Abstract: The present invention relates to a transdermal photocuring forming hydrogel with biological activity. The hydrogel can release recombinant collagen with biological activity, the recombinant collagen includes a sequence as shown in SEQ ID No. 1, an amino acid sequence of the recombinant collagen includes N basic repetitive units, and each basic repetitive unit includes n1 of the following characteristic amino acid sequences: “G-Xaa1-Xaa2-G-E-Xaa3”; the 3? end and the 5? end of the basic repetitive unit are connected to form the above characteristic amino acid sequence. The recombinant collagen provided by the present invention has relatively obvious integrin binding activity, and has the effects of promoting cell adhesion, proliferation and differentiation. The hydrogel of the present invention has good biocompatibility and stable quality, which can be cured and formed in situ in a transdermal photo-crosslinking manner after injection, with simple, convenient and controllable operation.Type: ApplicationFiled: October 8, 2023Publication date: April 25, 2024Inventors: Hai LIN, He QIU, Jing WANG, Jian WANG, Yang XU, Lu SONG, Xia YANG, Xingdong ZHANG
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Publication number: 20240115763Abstract: The present invention discloses a recombinant collagen protein and its use in the cartilage repair matrix. The present invention discloses a recombinant collagen protein which contains the sequence shown in SEQ ID No. 1; the amino acid sequence of the stated recombinant collagen protein comprises N basic repetitive units; the basic repetitive unit contains n1 amino acid sequences with the following characteristic: G-Xaa1-Xaa2-G-E-Xaa3; the 3? end and the 5? end of the basic repetitive unit are connected to form the amino acid sequence with the above characteristic. The recombinant collagen protein claimed by the present invention has significant integrin binding activity, has the effect of promoting cell adhesion, proliferation, differentiation, and repairing cartilage tissue defects, etc, and it has promising prospects for application.Type: ApplicationFiled: October 9, 2023Publication date: April 11, 2024Inventors: Hai LIN, Yang XU, Jing WANG, Zhanhong LIU, Xia YANG, Xingdong ZHANG
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Publication number: 20240093472Abstract: Disclosed is a water tank drainage volume control structure comprising: a water tank body (1), having a first water storage chamber (11) and a second water storage chamber (12), the first water storage chamber (11) being provided with a first drainage channel, and the second water storage chamber (12) being provided with a second drainage channel; a drainage valve (2), used for controlling the opening/closing of the second drainage channel, the drainage valve (2) being provided with a full-drainage switch and a half-drainage switch for controlling the opening of the second drainage channel; and a water blocking member (3), moving with respect to the water tank body (1) under the control of the full-drainage switch or the half-drainage switch so as to control switching of the first drainage channel between open and closed states. The present invention uses a drainage valve to control drainage, can also achieve half drainage and full drainage of a water tank, and is simple in structure and reliable in function.Type: ApplicationFiled: January 7, 2021Publication date: March 21, 2024Inventors: Rongyu ZHANG, Xingdong WANG
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Patent number: 11844880Abstract: A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.Type: GrantFiled: May 26, 2021Date of Patent: December 19, 2023Assignees: Sichuan University, Shanxi Jinbo Bio-Pharmaceutical Co., LtdInventors: Yunbing Wang, Li Yang, Rifang Luo, Lu Lu, Xia Yang, Xingdong Zhang
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Publication number: 20210369923Abstract: A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.Type: ApplicationFiled: May 26, 2021Publication date: December 2, 2021Applicants: Sichuan University, Shanxi Jinbo Bio-Pharmaceutical Co., LtdInventors: Yunbing WANG, Li YANG, Rifang LUO, Lu LU, Xia YANG, Xingdong ZHANG
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Publication number: 20210322641Abstract: An anti-thrombotic and endothelialization-enhanced bioprosthetic valve material and preparation thereof are provided. The preparation method includes the following steps: immersing a glutaraldehyde cross-linked bioprosthetic valve material in functional reagent solution for 1-24 h, adjusting pH value of the solution to 3-8, removing it from solution and cleaning with deionized water. The new valve material of the present invention can effectively reduce the toxicity and side effects of the existing glutaraldehyde cross-linked bioprosthetic valve material and effectively reduce thrombosis, along with enhanced endothelialization. The material prepared can be used for pulmonary valve, aortic valve, mitral valve, tricuspid valve, venous valve and other cardiovascular implantable medical devices.Type: ApplicationFiled: April 21, 2021Publication date: October 21, 2021Applicant: Sichuan UniversityInventors: Li YANG, Yunbing WANG, Rifang LUO, Xingdong ZHANG
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Patent number: 10770251Abstract: An alternating current contactor comprises a base and a magnetic yoke. The magnetic yoke is mounted on a bottom plate of the base. A magnetic yoke support for supporting and buffering the magnetic yoke is respectively provided at two sides of the magnetic yoke, wherein sidewalls at two sides of each magnetic yoke support, which are connected with the magnetic yoke are different in thickness. The magnetic yoke support of the alternating current contactor of the utility model has a simple structure due to the arrangement of an asymmetric eccentric structure. The up-down position of the magnetic yoke relative to the bottom plate of the base can be adjusted by changing an assembly direction of the magnetic yoke supports, thereby achieving the purpose of adjusting the total stroke of the product with high flexibility.Type: GrantFiled: October 24, 2016Date of Patent: September 8, 2020Assignee: ZHEJIANG CHINT ELECTRICS CO., LTD.Inventors: Ping Xu, Yujia Hu, Xingdong Zhang, Zhiwen Zhang, Tifeng Xiao
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Publication number: 20180350543Abstract: An alternating current contactor comprises a base and a magnetic yoke. The magnetic yoke is mounted on a bottom plate of the base. A magnetic yoke support for supporting and buffering the magnetic yoke is respectively provided at two sides of the magnetic yoke, wherein sidewalls at two sides of each magnetic yoke support, which are connected with the magnetic yoke are different in thickness. The magnetic yoke support of the alternating current contactor of the utility model has a simple structure due to the arrangement of an asymmetric eccentric structure. The up-down position of the magnetic yoke relative to the bottom plate of the base can be adjusted by changing an assembly direction of the magnetic yoke supports, thereby achieving the purpose of adjusting the total stroke of the product with high flexibility.Type: ApplicationFiled: October 24, 2016Publication date: December 6, 2018Applicant: ZHEJIANG CHINT ELECTRICS CO., LTD.Inventors: Ping XU, Yujia HU, Xingdong ZHANG, Zhiwen ZHANG, Tifeng XIAO
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Patent number: 9681494Abstract: The present invention provides a split-type mobile terminal which includes a host and at least one sub-device connected to the host. Wherein, the host includes: a state obtaining unit (102A) configured to obtain a real-time state of the host when a communications event occurs in the host; a state determining unit (102B) configured to determine whether or not the real-time state is a preset interactive state; a data interacting unit (102C) configured to send a response command to at least one of the at least one sub-device if the determining result is yes; and a host processing unit (102D) configured to directly respond to the communications event if the determining result is no. Each sub-device includes a sub-device processing unit (1040) configured to respond to the communications event according to the received respond command. The present invention further provides an interaction processing method for a communications event.Type: GrantFiled: April 26, 2013Date of Patent: June 13, 2017Assignees: YULONG COMPUTER TELECOMMUNICATION SCIENTIFIC (SHENZHEN) CO., LTD., DONGGUAN YULONG TELECOMMUNICATION TECH CO., LTD.Inventors: Peng Song, Bin Guo, Xingdong Zhang
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Publication number: 20160081138Abstract: The present invention provides a split-type mobile terminal which includes a host and at least one sub-device connected to the host. Wherein, the host includes: a state obtaining unit (102A) configured to obtain a real-time state of the host when a communications event occurs in the host; a state determining unit (102B) configured to determine whether or not the real-time state is a preset interactive state; a data interacting unit (102C) configured to send a response command to at least one of the at least one sub-device if the determining result is yes; and a host processing unit (102D) configured to directly respond to the communications event if the determining result is no. Each sub-device includes a sub-device processing unit (1040) configured to respond to the communications event according to the received respond command. The present invention further provides an interaction processing method for a communications event.Type: ApplicationFiled: April 26, 2013Publication date: March 17, 2016Applicants: YULONG COMPUTER TELECOMMUNICATION SCIENTIFIC (SHENZHEN) CO., LTD., DONGGUAN YULONG TELECOMMUNICATION TECH CO., LTD.Inventors: Peng SONG, Bin GUO, Xingdong ZHANG