Patents by Inventor Xingdong Zhao

Xingdong Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for adjusting train diagram
    Patent number: 12002360
    Abstract: The present application discloses a method and apparatus for adjusting a train diagram, the method includes: obtaining a first time of an extra train corresponding to a target passenger flow, and obtaining a set of trains with adjustable departure times based on the first time, in which the set of trains includes at least one train; adjusting a departure time of the at least one train in the set of trains based on a preset minimum departure time interval to obtain an adjusted train diagram; and performing an extra train adding instruction based on the adjusted train diagram.
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: June 4, 2024
    Assignee: Traffic Control Technology Co., Ltd
    Inventors: Kai Lu, Ming Luo, Xingdong Zhao
  • SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20230406856
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 16, 2021
    Publication date: December 21, 2023
    Inventors: Haohan TAN, Qihong LIU, Yunling WANG, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS AS PROTEIN KINASE INHIBITORS
    Publication number: 20230174556
    Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: May 14, 2021
    Publication date: June 8, 2023
    Inventors: Zuwen ZHOU, Rui TAN, Hua XU, Qihong LIU, Huajie ZHANG, Bin LIU, Weipeng ZHANG, Zhifu LI, Yanxin LIU, Shu LIN, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS AS BCL-2 INHIBITORS
    Publication number: 20230159527
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: May 7, 2021
    Publication date: May 25, 2023
    Inventors: Weipeng ZHANG, Hongbin LIU, Rui TAN, Zhifu LI, Yue RONG, Qihong LIU, Zhifang CHEN, Ling CHEN, Hua XU, Zuwen ZHOU, Jinhua YU, Haohan TAN, Bin LIU, Yunling WANG, Lijun YANG, Chengxi HE, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS USEFUL AS KINASE INHIBITORS
    Publication number: 20230145305
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 10, 2021
    Publication date: May 11, 2023
    Inventors: Chengxi HE, Xianlong WANG, Yue RONG, Rui TAN, Huajie ZHANG, Haohan TAN, Yanxin LIU, Shu LIN, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS AS CDK2/4/6 INHIBITORS
    Publication number: 20230135215
    Abstract: Provided are certain CDK2/4/6 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: February 26, 2021
    Publication date: May 4, 2023
    Inventors: Huajie ZHANG, Hua XU, Chengxi HE, Ling CHEN, Lijun YANG, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • METHOD AND APPARATUS FOR ADJUSTING TRAIN DIAGRAM
    Publication number: 20230017198
    Abstract: The present application discloses a method and apparatus for adjusting a train diagram, the method includes: obtaining a first time of an extra train corresponding to a target passenger flow, and obtaining a set of trains with adjustable departure times based on the first time, in which the set of trains includes at least one train; adjusting a departure time of the at least one train in the set of trains based on a preset minimum departure time interval to obtain an adjusted train diagram; and performing an extra train adding instruction based on the adjusted train diagram.
    Type: Application
    Filed: December 28, 2021
    Publication date: January 19, 2023
    Applicant: Traffic Control Technology Co., Ltd.
    Inventors: Kai LU, Ming Luo, Xingdong Zhao
  • Macrocyclic compounds as TRK kinases inhibitors
    Patent number: 11555042
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: January 17, 2023
    Assignee: Fochon Biosciences, Ltd.
    Inventors: Huajie Zhang, Qihong Liu, Chengxi He, Weipeng Zhang, Rui Tan, Bin Liu, Hong Fu, Haohan Tan, Lijun Yang, Hongbin Liu, Yunling Wang, Yuwei Gao, Zongyao Zou, Yanxin Liu, Shu Lin, Tongshuang Li, Xingdong Zhao, Weibo Wang
  • APOPTOSIS-INDUCING AGENTS
    Publication number: 20220402913
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: July 15, 2021
    Publication date: December 22, 2022
    Inventors: Hongbin LIU, Yue RONG, Huajie ZHANG, Zhifang CHEN, Rui TAN, Chengxi HE, Zhifu LI, Zuwen ZHOU, Haohan TAN, Kai RAN, Xianlong WANG, Zongyao ZOU, Lihua JIANG, Yanxin LIU, Xingdong ZHAO, Weibo WANG, Jiemin FU
  • HETEROCYCLIC DERIVATIVES AND USE THEREOF
    Publication number: 20220354860
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: June 15, 2020
    Publication date: November 10, 2022
    Inventors: Zuwen ZHOU, Hua XU, Yue RONG, Ling CHEN, Zhifang CHEN, Rui TAN, Lijun YANG, Xianlong WANG, Haohan TAN, Bin LIU, Chenglin ZHOU, Yuwei GAO, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Deuterated compounds as rock inhibitors
    Patent number: 11485707
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds thereof, and use of these compounds in preparing drugs for inhibiting ROCK.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: November 1, 2022
    Assignee: Fochon Pharmaceuticals, Ltd.
    Inventors: Rui Tan, Weipeng Zhang, Yunling Wang, Xingdong Zhao, Tao Cheng, Shu Lin, Weibo Wang
  • Substituted 2-azabicyclo[3.1.0]hexanes as TRK kinases inhibitors
    Patent number: 11459332
    Abstract: Provided are certain TRK inhibitors of formula (I): pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: October 4, 2022
    Assignee: Fochon Biosciences, Ltd.
    Inventors: Hongbin Liu, Haohan Tan, Chengxi He, Xianlong Wang, Qihong Liu, Zhifu Li, Zuwen Zhou, Yuwei Gao, Lihua Jiang, Li Linghu, Shu Lin, Xingdong Zhao, Weibo Wang
  • SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3,4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20220235049
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: June 1, 2020
    Publication date: July 28, 2022
    Inventors: Haohan TAN, Qihong LIU, Bin LIU, Zhifu LI, Xianlong WANG, Zuwen ZHOU, Weipeng ZHANG, Yunling WANG, Chenglin ZHOU, Yuwei GAO, Lihua JIANG, Yanxin LIU, Zongyao ZOU, Shu LIN, Kai YU, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • PASSENGER-ORIENTED TRANSFER SYNCHRONIZATION OPTIMIZATION METHOD AND PASSENGER-ORIENTED TRANSFER SYNCHRONIZATION OPTIMIZATION DEVICE
    Publication number: 20220135087
    Abstract: A passenger-oriented transfer synchronization optimization method and a passenger-oriented transfer synchronization optimization device, in which minimizing average waiting time of passengers is taken as an optimization objective, and constraint conditions are determined based on the transfer-related information; an arrival time and a departure time of each train is adjusted on an original train diagram of lines to be adjusted, and an adjusted train diagram is determined; and the trains on the lines to be adjusted are controlled based on the adjusted train diagram. Urban rail transit train diagrams for complex lines can be made, and no manual participation is required when adjusting the train diagrams, which can not only improve the adjustment efficiency, but also ensure the adjustment effect by avoiding errors caused by manual adjustments. The transfer efficiency of passengers can be improved when making transfers, and all-day transfer synchronizations can be optimized.
    Type: Application
    Filed: January 7, 2021
    Publication date: May 5, 2022
    Inventors: Nan Cao, Ming Luo, Xingdong Zhao
  • SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
    Publication number: 20220041588
    Abstract: Provided are certain RET inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 26, 2019
    Publication date: February 10, 2022
    Inventors: Chengxi HE, Rui TAN, Zuwen ZHOU, Weipeng ZHANG, Yunling WANG, Qihong LIU, Xingdong ZHAO, Yanxin LIU, Yuwei GAO, Shu LIN, Weibo WANG
  • Sulfoximine, sulfonimidamide, sulfondiimine and diimidosulfonamide compounds as inhibitors of indoleamine 2,3-dioxygenase
    Patent number: 11168078
    Abstract: Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: November 9, 2021
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Zhifang Chen, Rui Tan, Qihong Liu, Lijun Yang, Zhifu Li, Haohan Tan, Hongbin Liu, Xingdong Zhao, Min Lin, Jing Sun, Weibo Wang
  • Apoptosis-inducing agents
    Patent number: 11091478
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: August 17, 2021
    Assignee: Fochon Pharmaceutical Co., Ltd.
    Inventors: Hongbin Liu, Yue Rong, Huajie Zhang, Zhifang Chen, Rui Tan, Chengxi He, Zhifu Li, Zuwen Zhou, Haohan Tan, Kai Ran, Xianlong Wang, Zongyao Zou, Lihua Jiang, Yanxin Liu, Xingdong Zhao, Weibo Wang, Jiemin Fu
  • Compounds as BLC-2-selective apoptosis-inducing agents
    Patent number: 11053239
    Abstract: Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bcl-2 inhibitors can be used to treat cell proliferative disorders.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: July 6, 2021
    Assignee: Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Zuwen Zhou, Chengxi He, Zhifu Li, Yue Rong, Rui Tan, Huajie Zhang, Hongbin Liu, Weipeng Zhang, Haohan Tan, Zhifang Chen, Lihua Jiang, Yanxin Liu, Min Lin, Jing Sun, Weibo Wang
  • Electronic device
    Patent number: D994664
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: August 8, 2023
    Assignee: Elo Touch Solutions, Inc.
    Inventors: David Noppenberger, Wei Wang, Xingdong Zhao, Hui Yang
  • Electronic device
    Patent number: D1015329
    Type: Grant
    Filed: May 30, 2023
    Date of Patent: February 20, 2024
    Assignee: Elo Touch Solutions, Inc.
    Inventors: David Noppenberger, Wei Wang, Xingdong Zhao, Hui Yang