Abstract: Disclosed are a derivative of a 2,5-diketopiperazine compound, and a preparation method therefor, a pharmaceutical composition thereof and the use thereof. Specifically, disclosed are a compound as represented by formula (I), a stereoisomer thereof, a tautomer thereof or a pharmaceutically acceptable salt thereof, or a solvate of any one of the aforementioned. The compound is new in terms of structure, and has good anti-tumor activity and water solubility.

Abstract: Disclosed is an optimal power flow acquiring method for regional distribution network of small hydropower groups based on deep learning, which specifically includes the following steps: generating required data sets by adopting continuous power flow and power flow equation calculation methods; the data set is randomly divided into training data (80 percent) and test data (20 percent); training the built convolutional neural network model with training data to learn the mapping relationship between load and generator output power; inputting test data, and directly obtaining PG and QG from the trained convolutional neural network; and solving residual variables Vi and ?i with traditional power flow solver. The application can accelerate the solving speed of the optimal power flow problem with higher prediction accuracy.

Abstract: A microwave resonant cavity for laser cooling, microwave interrogation, and atomic state detection, comprising a microwave resonant cavity body, two cutoff waveguide end covers, and four waveguides for laser beams and microwave coupling. The cavity feeds not only microwave but also laser beams into the center of the cavity. In a vacuum chamber with target atoms, the target atoms may be trapped and cooled in the center of the cavity. By sequential operation of the resonant microwave and lasers, the microwave resonant cavity of the present invention may manipulate and detect the atomic state population and interrogate the energy level of the cold atoms in situ. The invention may be applied to the fields of atomic frequency standard, interferometer and atomic gyro for developing the miniaturized cold atoms related precision measurement equipment.

Abstract: A microwave resonant cavity for laser cooling, microwave interrogation, and atomic state detection, comprising a microwave resonant cavity body, two cutoff waveguide end covers, and four waveguides for laser beams and microwave coupling. The cavity feeds not only microwave but also laser beams into the center of the cavity. In a vacuum chamber with target atoms, the target atoms may be trapped and cooled in the center of the cavity. By sequential operation of the resonant microwave and lasers, the microwave resonant cavity of the present invention may manipulate and detect the atomic state population and interrogate the energy level of the cold atoms in situ. The invention may be applied to the fields of atomic frequency standard, interferometer and atomic gyro for developing the miniaturized cold atoms related precision measurement equipment.

Abstract: Disclosed is a composition for extracting mycotoxins or aflatoxins from a food sample. The methods using the composition to detect and analyze the aflatoxins are also provided.

Abstract: A polyelectrolyte having multiple exposed functional groups, each such group being capable of covalently bonding to a molecule, is immobilized on a surface for the purpose of bonding to a biomolecule. The biomolecule can be, for example, a nucleic acid, e.g., an amine functionalized oligonucleotide. The polyelectrolyte can include, e.g., BSA (Bovine Serum Albumin) which is bound to a functionalized surface using a covalent immobilization strategy, e.g., reaction with the surface of a tosyl-activated microparticle. Following such reaction, exposed reactive functional groups on the protein, such as amine, carboxyl, thiol, hydroxyl groups can further be utilized to covalently couple the oligonucleotide of interest using suitable chemistry.

Abstract: A polyelectrolyte having multiple exposed functional groups, each such group being capable of covalently bonding to a molecule, is immobilized on a surface for the purpose of bonding to a biomolecule. The biomolecule can be, for example, a nucleic acid, e.g., an amine functionalized oligonucleotide. The polyelectrolyte can include, e.g., BSA (Bovine Serum Albumin) which is bound to a functionalized surface using a covalent immobilization strategy, e.g., reaction with the surface of a tosyl-activated microparticle. Following such reaction, exposed reactive functional groups on the protein, such as amine, carboxyl, thiol, hydroxyl groups can further be utilized to covalently couple the oligonucleotide of interest using suitable chemistry.

Abstract: Disclosed are proteins which are covalently bound to a solid support at a first temperature where they have a first configuration, and then biomolecules are attached to the bound proteins at a higher temperature at which the proteins have more exposed functional groups, each such group being capable of covalently bonding to a biomolecule. The biomolecule can be, for example, a nucleic acid, including an amine functionalized oligonucleotide. The proteins can include, BSA (Bovine Serum Albumin) which can be bound using a reaction with the surface of a tosyl-activated microparticle.

Abstract: A polyelectrolyte having multiple exposed functional groups, each such group being capable of covalently bonding to a molecule, is immobilized on a surface for the purpose of bonding to a biomolecule. The biomolecule can be, for example, a nucleic acid, e.g., an amine functionalized oligonucleotide. The polyelectrolyte can include, e.g., BSA (Bovine Serum Albumin) which is bound to a functionalized surface using a covalent immobilization strategy, e.g., reaction with the surface of a tosyl-activated microparticle. Following such reaction, exposed reactive functional groups on the protein, such as amine, carboxyl, thiol, hydroxyl groups can further be utilized to covalently couple the oligonucleotide of interest using suitable chemistry.

Abstract: Disclosed are proteins which are covalently bound to a solid support at a first temperature where they have a first configuration, and then biomolecules are attached to the bound proteins at a higher temperature at which the proteins have more exposed functional groups, each such group being capable of covalently bonding to a biomolecule. The biomolecule can be, for example, a nucleic acid, e.g., an amine functionalized oligonucleotide. The proteins can include, e.g., BSA (Bovine Serum Albumin) which can be bound using a reaction with the surface of a tosyl-activated microparticle.

Abstract: A polyelectrolyte having multiple exposed functional groups, each such group being capable of covalently bonding to a molecule, is immobilized on a surface for the purpose of bonding to a biomolecule. The biomolecule can be, for example, a nucleic acid, e.g., an amine functionalized oligonucleotide. The polyelectrolyte can include, e.g., BSA (Bovine Serum Albumin) which is bound to a functionalized surface using a covalent immobilization strategy, e.g., reaction with the surface of a tosyl-activated microparticle. Following such reaction, exposed reactive functional groups on the protein, such as amine, carboxyl, thiol, hydroxyl groups can further be utilized to covalently couple the oligonucleotide of interest using suitable chemistry.