Patents by Inventor XIONGBO CHEN

XIONGBO CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BISPECIFIC CS1-BCMA CAR-T CELL AND APPLICATION THEREOF
    Publication number: 20240082401
    Abstract: The present invention provides a bispecific CS1-BCMA CAR-T cell and an application thereof. Specifically, the present invention provides a bispecific CAR, which comprises CS1 scFv and BCMA scFv, and a 4-1BB co-stimulatory domain and a CD3 activation domain. The bispecific CAR-T cell in the present invention has a significant killing effect on CS1 positive target cells and BCMA positive target cells, and can secrete IFN-? against target cells and significantly inhibit the growth of RPMI8226 xenograft tumor in an in vivo experiment. The present invention further provides a preparation method and an application of the bispecific CAR-T cell.
    Type: Application
    Filed: January 26, 2022
    Publication date: March 14, 2024
    Inventors: Lianjun ZHANG, Heng MEI, Tangyi ZHOU, Xiongbo CHEN, Wei XIONG
  • Waste gas purification system and method
    Patent number: 11014044
    Abstract: A waste gas purification system according to an embodiment includes an adsorption-catalysis-oxidation unit, an enhanced absorption unit, an air inducing unit, and a flue gas discharge and heat exchange unit that are sequentially connected. The waste gas enters a heat exchange device of the flue gas discharge and heat exchange unit through a first waste gas delivery pipeline to perform heat exchange, then is converged with waste gas in a second waste gas delivery pipeline and enters a third waste gas delivery pipeline. Waste gas in the third waste gas delivery pipeline is purified after sequentially passing through the adsorption-catalysis-oxidation unit and the enhanced absorption unit. Purified flue gas is introduced into the flue gas discharge and heat exchange unit by the air inducing unit, and the purified flue gas is discharged after performing heat exchange with the heat exchange device.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: May 25, 2021
    Assignee: South China Institute of Environmental Science, MEE
    Inventors: Ping Fang, Chaoping Cen, Zijun Tang, Xiongbo Chen, Jianhang Huang
  • WASTE GAS PURIFICATION SYSTEM AND METHOD
    Publication number: 20200070090
    Abstract: A waste gas purification system according to an embodiment includes an adsorption-catalysis-oxidation unit, an enhanced absorption unit, an air inducing unit, and a flue gas discharge and heat exchange unit that are sequentially connected. The waste gas enters a heat exchange device of the flue gas discharge and heat exchange unit through a first waste gas delivery pipeline to perform heat exchange, then is converged with waste gas in a second waste gas delivery pipeline, and enters a third waste gas delivery pipeline. Waste gas in the third waste gas delivery pipeline is purified after sequentially passing through the adsorption-catalysis-oxidation unit and the enhanced absorption unit. Purified flue gas is introduced into the flue gas discharge and heat exchange unit by the air inducing unit, and the purified flue gas is discharged after performing heat exchange with the heat exchange device.
    Type: Application
    Filed: April 19, 2019
    Publication date: March 5, 2020
    Inventors: PING FANG, CHAOPING CEN, ZIJUN TANG, XIONGBO CHEN, JIANHANG HUANG