Patents by Inventor Xuan S. Bui
Xuan S. Bui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220090994Abstract: An apparatus including a reagent cartridge and a reaction chamber, the reagent cartridge having a reagent capsule removably positioned therein for dispensing of a reagent onto the reaction chamber. A system including a linearly translatable mounting assembly having a plurality of mounting stations dimensioned to receive at least one fluid dispensing cartridge, a linearly translatable bulk reagent dispensing assembly having a plurality of bulk reagent dispensing nozzles coupled thereto and a receiving assembly positioned beneath the mounting assembly and the bulk reagent dispensing assembly, the receiving assembly including a plurality of reaction stations.Type: ApplicationFiled: December 6, 2021Publication date: March 24, 2022Applicant: Sakura Finetek U.S.A., Inc.Inventors: Xuan S. Bui, Anthony L. Hartman, Toshiyuki Fujimaki, Shinji Tokudaiji, Yoshitake Okabe, Yoshitada Mizusawa
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Patent number: 11193859Abstract: An apparatus including a reagent cartridge and a reaction chamber, the reagent cartridge having a reagent capsule removably positioned therein for dispensing of a reagent onto the reaction chamber. A system including a linearly translatable mounting assembly having a plurality of mounting stations dimensioned to receive at least one fluid dispensing cartridge, a linearly translatable bulk reagent dispensing assembly having a plurality of bulk reagent dispensing nozzles coupled thereto and a receiving assembly positioned beneath the mounting assembly and the bulk reagent dispensing assembly, the receiving assembly including a plurality of reaction stations.Type: GrantFiled: May 20, 2019Date of Patent: December 7, 2021Assignee: Sakura Finetek U.S.A., Inc.Inventors: Xuan S. Bui, Anthony L. Hartman, Toshiyuki Fujimaki, Shinji Tokudaiji, Yoshitake Okabe, Yoshitada Mizusawa
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Patent number: 11193950Abstract: An apparatus including a receptacle including a slot for receiving a basket; a push bar disposed in the receptacle, the push bar having an end to contact an edge of a single slide of a plurality of slides in a basket, the push bar including a first position below a bottom surface of a base of a basket that is received in the slot and a second position in the slot; and a sensor focused in a direction of the slot operable to acquire information from a slide in a received basket. A method including placing a slide basket into a slot of a receptacle; individually raising one or more slides from a respective position in the basket; using a sensor, acquiring information from the raised slide in the basket; and after acquiring information, lowering the raised slide.Type: GrantFiled: March 29, 2019Date of Patent: December 7, 2021Assignee: SAKURA FINETEK U.S.A., INC.Inventors: Erico von Bueren, Niccolo von Bueren, Xuan S. Bui
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Patent number: 11187625Abstract: An apparatus having a sample sectioning device including a cutting mechanism that is operable to cut sections from a sample and a sample holder that is operable to hold the sample. The apparatus further includes a drive system coupled with the sample holder to drive movement of the sample holder and a reciprocating member coupled to the drive system to drive vertical movement of the drive system. The reciprocating member to move in a reciprocating manner within an angle of rotation of less than 180 degrees. A surface orientation sensor may further be provided that is operable to sense an orientation of a surface of the sample held by the sample holder.Type: GrantFiled: February 13, 2018Date of Patent: November 30, 2021Assignee: SAKURA FINEIEK U.S.A., INC.Inventors: Hwai-Jyh Michael Yang, Xuan S. Bui
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Patent number: 11112337Abstract: A sample sectioning device including a cutting mechanism that is operable to cut sections from a sample, a sample holder operable to move relative to the cutting mechanism, the sample holder having a first side and a second side, the first side faces the cutting mechanism and is dimensioned to receive a sample, a light source coupled to the sample holder, wherein the light source is operable to emit a light from the first side of the sample holder and through a sample positioned on the first side, and a generator operable to generate an electrical energy for providing power to the light source.Type: GrantFiled: November 13, 2017Date of Patent: September 7, 2021Assignee: SAKURA FINETEK U.S.A., INC.Inventors: Xuan S. Bui, Alyicia Marie Rios, Erico Von Bueren
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Publication number: 20200309800Abstract: An apparatus including a receptacle including a slot for receiving a basket; a push bar disposed in the receptacle, the push bar having an end to contact an edge of a single slide of a plurality of slides in a basket, the push bar including a first position below a bottom surface of a base of a basket that is received in the slot and a second position in the slot; and a sensor focused in a direction of the slot operable to acquire information from a slide in a received basket. A method including placing a slide basket into a slot of a receptacle; individually raising one or more slides from a respective position in the basket; using a sensor, acquiring information from the raised slide in the basket; and after acquiring information, lowering the raised slide.Type: ApplicationFiled: March 29, 2019Publication date: October 1, 2020Applicant: SAKURA FINETEK U.S.A., INC.Inventors: Erico von Bueren, Niccolo von Bueren, Xuan S. Bui
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Patent number: 10466143Abstract: A microtome including a microtome housing having a base portion, a front portion and a top portion, a microtome storage member associated with the top portion of the microtome housing, and a sample sectioning assembly associated with the front portion of the microtome housing, the sample sectioning assembly operable to cut sections from a sample.Type: GrantFiled: November 13, 2017Date of Patent: November 5, 2019Assignee: Sakura Finetek U.S.A., Inc.Inventors: Xuan S. Bui, Alyicia Marie Rios, Erico Von Bueren
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Patent number: 10422724Abstract: A sample sectioning device including a housing having a base member, a cutting mechanism positioned on the base member and operable to cut sections from a sample, a sample holder dimensioned to hold a sample and operable to move with respect to the cutting mechanism during a cutting operation, and a waste removal assembly positioned below the cutting mechanism and the sample holder, the waste removal assembly having a first member and a second member that are dimensioned to remove waste produced during the cutting operation.Type: GrantFiled: November 13, 2017Date of Patent: September 24, 2019Assignee: Sakura Finetek U.S.A., Inc.Inventors: Xuan S. Bui, Alyicia Marie Rios, Erico Von Bueren
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Publication number: 20190271618Abstract: An apparatus including a reagent cartridge and a reaction chamber, the reagent cartridge having a reagent capsule removably positioned therein for dispensing of a reagent onto the reaction chamber. A system including a linearly translatable mounting assembly having a plurality of mounting stations dimensioned to receive at least one fluid dispensing cartridge, a linearly translatable bulk reagent dispensing assembly having a plurality of bulk reagent dispensing nozzles coupled thereto and a receiving assembly positioned beneath the mounting assembly and the bulk reagent dispensing assembly, the receiving assembly including a plurality of reaction stations.Type: ApplicationFiled: May 20, 2019Publication date: September 5, 2019Applicant: SAKURA FINETEK U.S.A., INC.Inventors: Xuan S. Bui, Anthony L. Hartman, Toshiyuki Fujimaki, Shinji Tokudaiji, Yoshitake Okabe, Yoshitada Mizusawa
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Patent number: 10295444Abstract: An apparatus including a reagent cartridge and a reaction chamber, the reagent cartridge having a reagent capsule removably positioned therein for dispensing of a reagent onto the reaction chamber. A system including a linearly translatable mounting assembly having a plurality of mounting stations dimensioned to receive at least one fluid dispensing cartridge, a linearly translatable bulk reagent dispensing assembly having a plurality of bulk reagent dispensing nozzles coupled thereto and a receiving assembly positioned beneath the mounting assembly and the bulk reagent dispensing assembly, the receiving assembly including a plurality of reaction stations.Type: GrantFiled: December 22, 2014Date of Patent: May 21, 2019Assignee: Sakura Finetek U.S.A., Inc.Inventors: Xuan S. Bui, Anthony L. Hartman, Toshiyuki Fujimaki, Shinji Tokudaiji, Yoshitake Okabe, Yoshitada Mizusawa
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Patent number: 10012567Abstract: A microtome chuck including a mounting portion having a mating surface operable to removably attach the mounting portion to a sample sectioning device, and an electrical contact operable to electrically connect the mounting portion to a power source. The chuck further including a sample receiving portion coupled to the mounting portion, the sample receiving portion having a sample receiving surface dimensioned to receive a sample, a light source coupled to the sample receiving portion, the light source operable to emit a light from the sample receiving surface and through a sample positioned along the sample receiving surface, and circuitry electrically connecting the light source to the electrical contact of the mounting portion.Type: GrantFiled: November 13, 2017Date of Patent: July 3, 2018Assignee: Sakura Finetek U.S.A., Inc.Inventors: Xuan S. Bui, Alyicia Marie Rios, Erico Von Bueren
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Publication number: 20180172558Abstract: An apparatus having a sample sectioning device including a cutting mechanism that is operable to cut sections from a sample and a sample holder that is operable to hold the sample. The apparatus further includes a drive system coupled with the sample holder to drive movement of the sample holder and a reciprocating member coupled to the drive system to drive vertical movement of the drive system. The reciprocating member to move in a reciprocating manner within an angle of rotation of less than 180 degrees. A surface orientation sensor may further be provided that is operable to sense an orientation of a surface of the sample held by the sample holder.Type: ApplicationFiled: February 13, 2018Publication date: June 21, 2018Inventors: Hwai-Jyh Michael Yang, Xuan S. Bui
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Publication number: 20180136090Abstract: A microtome chuck including a mounting portion having a mating surface operable to removably attach the mounting portion to a sample sectioning device, and an electrical contact operable to electrically connect the mounting portion to a power source. The chuck further including a sample receiving portion coupled to the mounting portion, the sample receiving portion having a sample receiving surface dimensioned to receive a sample, a light source coupled to the sample receiving portion, the light source operable to emit a light from the sample receiving surface and through a sample positioned along the sample receiving surface, and circuitry electrically connecting the light source to the electrical contact of the mounting portion.Type: ApplicationFiled: November 13, 2017Publication date: May 17, 2018Inventors: Xuan S. Bui, Alyicia Marie Rios, Erico Von Bueren
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Publication number: 20180136087Abstract: A sample sectioning device including a housing having a base member, a cutting mechanism positioned on the base member and operable to cut sections from a sample, a sample holder dimensioned to hold a sample and operable to move with respect to the cutting mechanism during a cutting operation, and a waste removal assembly positioned below the cutting mechanism and the sample holder, the waste removal assembly having a first member and a second member that are dimensioned to remove waste produced during the cutting operation.Type: ApplicationFiled: November 13, 2017Publication date: May 17, 2018Inventors: Xuan S. Bui, Alyicia Marie Rios, Erice Von Bueren
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Publication number: 20180136089Abstract: A sample sectioning device including a cutting mechanism that is operable to cut sections from a sample, a sample holder operable to move relative to the cutting mechanism, the sample holder having a first side and a second side, the first side faces the cutting mechanism and is dimensioned to receive a sample, a light source coupled to the sample holder, wherein the light source is operable to emit a light from the first side of the sample holder and through a sample positioned on the first side, and a generator operable to generate an electrical energy for providing power to the light source.Type: ApplicationFiled: November 13, 2017Publication date: May 17, 2018Inventors: Xuan S. Bui, Alyicia Marie Rios, Erico Von Bueren
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Publication number: 20180136088Abstract: A microtome including a microtome housing having a base portion, a front portion and a top portion, a microtome storage member associated with the top portion of the microtome housing, and a sample sectioning assembly associated with the front portion of the microtome housing, the sample sectioning assembly operable to cut sections from a sample.Type: ApplicationFiled: November 13, 2017Publication date: May 17, 2018Inventors: Xuan S. Bui, Alyicia Marie Rios, Erico Von Bueren
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Patent number: 9921137Abstract: An apparatus having a sample sectioning device including a cutting mechanism that is operable to cut sections from a sample and a sample holder that is operable to hold the sample. The apparatus further includes a drive system coupled with the sample holder to drive movement of the sample holder and a reciprocating member coupled to the drive system to drive vertical movement of the drive system. The reciprocating member to move in a reciprocating manner within an angle of rotation of less than 180 degrees. A surface orientation sensor may further be provided that is operable to sense an orientation of a surface of the sample held by the sample holder.Type: GrantFiled: May 12, 2015Date of Patent: March 20, 2018Assignee: Sakura Finetek U.S.A., Inc.Inventors: Hwai-Jyh Michael Yang, Xuan S. Bui
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Patent number: 9914124Abstract: A fluid dispensing apparatus includes a fluid reservoir and a dispensing assembly. The dispensing assembly includes a housing and a deformable member that define a metering chamber that is configured to receive a predetermined volume of fluid from the fluid reservoir. The deformable member is deformed from a rest position to an eject position and the deformation causes the volume of the metering chamber to change which results in a change in fluid pressure within the metering chamber. An increase in the fluid pressure within metering chamber causes a predetermined volume of fluid within the metering chamber to be ejected and a decrease in the fluid pressure within the metering chamber causes fluid to be drawn into the metering chamber from the reservoir.Type: GrantFiled: June 10, 2013Date of Patent: March 13, 2018Assignee: SAKURA FINETEK U.S.A., INC.Inventor: Xuan S. Bui
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Patent number: 9347857Abstract: A sample sectioning device includes a cutting mechanism, a sample holder, a drive system, and a surface orientation sensor. The sample holder is operable to hold a sample. The cutting mechanism is operable to cut sections from the sample. The drive system is coupled with the sample holder. The drive system is operable to drive movement between the sample held by the sample holder and the cutting mechanism. The surface orientation sensor is operable to sense an orientation of a surface of the sample held by the sample holder.Type: GrantFiled: September 30, 2014Date of Patent: May 24, 2016Assignee: Sakura Finetek U.S.A., Inc.Inventors: Hwai-Jyh Michael Yang, Xuan S. Bui
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Publication number: 20150241861Abstract: An apparatus having a sample sectioning device including a cutting mechanism that is operable to cut sections from a sample and a sample holder that is operable to hold the sample. The apparatus further includes a drive system coupled with the sample holder to drive movement of the sample holder and a reciprocating member coupled to the drive system to drive vertical movement of the drive system. The reciprocating member to move in a reciprocating manner within an angle of rotation of less than 180 degrees. A surface orientation sensor may further be provided that is operable to sense an orientation of a surface of the sample held by the sample holder.Type: ApplicationFiled: May 12, 2015Publication date: August 27, 2015Inventors: Hwai-Jyh Michael Yang, Xuan S. Bui