Abstract: The present disclosure relates to a color-changing composition and to a substrate having the color-changing compositions disposed thereon. The color-changing composition includes a leuco dye, a color-developer and a desensitizer. The color-changing composition changes from a colorless or largely colorless composition to color upon being wetted with an aqueous liquid. The color-changing composition remains colorless or largely colorless prior to exposure to high relative humidity conditions.

Abstract: The present invention relates to a color-changing material and to a multiple-component material that includes a color-changing composition. The color-changing materials and color-changing compositions are capable of changing color in order to indicate a change in condition, such as a change in pH. The color-changing materials and color-changing compositions include a hydrogel-forming composition, a charged colorant and a pH adjuster. The hydrogel-forming composition includes at least one charged species.

Abstract: A lateral flow assay device for determining the relative ionic strength of urine is described. The device includes a buffering zone having a polyelectrolyte disposed therein, and an indicator zone having a pH indicator non-diffusively immobilized therein, the indicator zone being separate from the buffering zone and positioned adjacent to and in fluid communication with the buffering zone. A detection zone is part of the buffering zone, and has a buffering component comprising a weak polymeric acid and weak polymeric base with a pKa ?10?3, and a class of charged polymeric surfactants that are responsive to relative ion concentrations in a sample solution, and a charged pH indicator with a charge opposite to that of the charged polymeric surfactant. The charged polymeric surfactant is soluble in amounts of greater than or equal to about 1% by weight (?1 wt. % solute) in water and aqueous solutions of low ionic concentration of ?0.1 wt. % salts, but insoluble (<1 wt.

Abstract: A lateral flow, membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes phosphorescence to detect the signals generated by excited phosphorescent labels. The labels may have a long emission lifetime so that background interference from many sources, such as scattered light and autofluorescence, is practically eliminated during detection. In addition, the phosphorescent labels may be encapsulated within particles to shield the labels from quenchers, such as oxygen or water, which might disrupt the phosphorescent signal.

Abstract: A diagnostic test kit for detecting the presence or absence of a protease (e.g., aminopeptidase) within a test sample is provided. The test kit comprises a substrate that is capable of being cleaved in the presence of the protease to release a compound. The kit also comprises a lateral flow device that comprises a chromatographic medium. The chromatographic medium defines a detection zone within which is contained a first reagent (e.g., diazonium ion) that is capable of reacting with the compound to form a second reagent (e.g., aromatic azo compound). The second reagent exhibits a color that is different than the color of the first reagent. The lateral flow device also includes an absorbent material located adjacent to the chromatographic medium, the absorbent material receiving the test sample after flowing through the chromatographic medium.

Abstract: A dryness indicator includes a wicking strip continuous between a reservoir end and an opposed open end; a liquid-impermeable top layer disposed on one side of the wicking strip; and a liquid-impermeable bottom layer disposed on the opposite side of the wicking strip, wherein the top layer is affixed to the bottom layer to at least partially enclose the wicking strip, and wherein the indicator is configured such that the open end of the wicking strip can be placed in liquid communication with an object or surface. The dryness indicator also includes a reservoir including an oil-based colorant with the potential to be in liquid communication with the reservoir end of the wicking strip, wherein the wicking strip is configured such that colorant wicking from the reservoir end and an unreacted water-based fluid wicking from the open end meet to define a timing line.

Abstract: An ink formulation that includes a reversible color-developing complex formed from a dye precursor molecule having a triarylmethane derivative structure modified with a leaving-group (L) that disassociates from said dye precursor when subjected to environmental conditions of either a neutral or acidic pH value is described. Also the invention pertains to diagnostic indicators or absorbent personal care products that have the ink formulation applied to at least a part of the product.

Abstract: A lateral flow, membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes phosphorescence to detect the signals generated by excited phosphorescent labels. The labels may have a long emission lifetime so that background interference from many sources, such as scattered light and autofluorescence, is practically eliminated during detection. In addition, the phosphorescent labels may be encapsulated within particles to shield the labels from quenchers, such as oxygen or water, which might disrupt the phosphorescent signal.

Abstract: An absorbent article comprises a signal element having a body-facing surface, a garment-facing surface, a longitudinal direction, a transverse direction and a z-direction. The signal element includes a water-soluble polymeric buffering film and a stimulation material. The water-soluble polymeric buffering film comprises a water-soluble base polymer. In some aspects, the stimulation material comprises a temperature change agent, and the signal element exhibits a surface temperature change of at least +/?2° C. In some aspects, the signal element exhibits a stimulation effect over at least two aqueous insults.

Abstract: Anti-viral tissues are provided with a pH indicator which can communicate to a tissue user by means of visual indicia, via color changes, that the tissue has active ingredients. Furthermore, the pH indicators can be used to illustrate neutralization of the pH of infected nasal discharge, which has a higher pH than healthy nasal discharge, giving the user a reason to believe that the product is working to deactivate virus.

Abstract: A personal absorbent article (e.g., feminine care pad, sanitary napkin, diaper, incontinence pad etc.) has a color change indicator that employs a synergistic combination an acid component and a basic component for signaling to a user when the absorbent article may foster bacterial growth due to moisture absorption. After a certain period of time, the user can visually inspect the color of the color change indicator to obtain an indication of when it is time to replace or remove the article.

Abstract: A dynamic inflatable pillow for toilet training children has a compartment wherein a gas-generating composition disposed. Once water enters the pillow compartment through water permeable sides, gas is generated and bubbles are released from at least one gas-release outlet. Dyes may be added to the gas-generating composition to create colored effluent. Functional dyes may be printed on the pillow surface(s), which may appear or, disappear when wetted.

Abstract: A diagnostic test kit for detecting the presence or quantity of an enzyme or enzyme inhibitor is provided. The diagnostic kit utilizes reactive complexes to facilitate the detection of the enzyme or enzyme inhibitor. The reactive complexes include a substrate joined (e.g., covalently bonded, physically adsorbed, etc.) to a reporter and specific binding member. In one embodiment, for example, a peptide, protein, or glycoprotein substrate is joined to a reporter (e.g., dyed latex particle) and specific binding member (e.g., biotinylated compound). In this embodiment, the substrate provides a cleavage target for a proteolytic enzyme. Specifically, upon contacting the reactive complexes, the proteolytic enzyme cleaves the substrate and releases the reporter and/or specific binding member. The signal exhibited by the released reporters may then be used to indicate the presence or quantity of an enzyme or enzyme inhibitor within the test sample.

Abstract: The invention describes a color-developing composition that contains at least three major components: (1) a leuco dye or a combination of leuco dyes, (2) an color-developer or a combination of color-developers that can form colored complexes with the leuco dyes, and (3) a desensitizer to temporarily remove the effect of the developer so the leuco dye appears in its colorless form. An optional binder may be included so that the composition may be applied to a substrate as an ink. The ink composition may be applied to synthetic polymeric substrates and other substrates that are incorporated into absorbent articles or personal care products.

Abstract: A wetness indicator material may be used on a substrate to form a wetness sensor. The sensor may show either the presence or absence of an aqueous-based fluid or water-containing medium, such as vaginal fluid or urine in a personal hygiene article. The wetness sensor may be incorporated into the article. The wetness indicator material includes a standard colorant that does not change color when wetted. The standard colorant increases the range of hues exhibited by the wetness indicator material.

Abstract: The present invention relates to a color-changing material and to a multiple-component material that includes a color-changing composition. The color-changing materials and color-changing compositions are capable of changing color in order to indicate a change in condition, such as a change in pH. The color-changing materials and color-changing compositions include a hydrogel-forming composition, a charged colorant and a pH adjuster. The hydrogel-forming composition includes at least one charged species.

Abstract: The present invention relates to a color-changing material and to a multiple-component material that includes a color-changing composition. The color-changing materials and color-changing compositions are capable of changing color in order to indicate a change in condition, such as a change in pH. The color-changing materials and color-changing compositions include a hydrogel-forming composition, a charged colorant and a pH adjuster. The hydrogel-forming composition includes at least one charged species.

Abstract: Signaling systems are disclosed that indicate a change in an absorbent article, such as the presence of a body fluid. The various different signaling systems disclosed do not include any conductive elements contained on the interior of the article as were required in the past. Instead, the changes are monitored from the outer cover of the article. In one embodiment, for instance, conductive zones are formed directly into the outer cover for forming the signaling system. Alternatively, a sensor may be mounted to the outer cover of the article for monitoring changes within the article. The sensor may comprise, for instance, a temperature sensor, a conductivity sensor, an optical sensor, a vibration sensor, a humidity sensor, a material expansion sensor, a chemical sensor, or the like.

Abstract: A feminine care absorbent article (e.g., feminine care pad, sanitary napkin, tampon, etc.) is provided that employs a synergistic combination of an antimicrobial composition for inhibiting the growth of microorganisms (e.g., bacteria, protozoa, yeast, fungi, etc.) and a pH sensor for signaling to the user when the antimicrobial composition is no longer operating at its full capacity. In this manner, the user can initially wear the article without fear of infection. After a certain period of time, the user can visually inspect the color of the pH sensor to obtain an indication of whether the antimicrobial composition is still active and effective in inhibiting microorganism growth, or whether it is time to replace or remove the article.

Abstract: In accordance with one embodiment of the present disclosure an absorbent article capable of indicating the presence or absence of urine as well as impending leakage of urine is disclosed. The absorbent article includes a substantially liquid impermeable layer, a liquid permeable layer, and an absorbent core positioned between the substantially liquid impermeable layer and the liquid permeable layer. A plurality of sensors are integrated into the article across the width of the article and positioned such that the sensors are in fluid communication with urine when provided by a wearer of the article. At least one of the sensors comprises a pH indicator. At least one of the sensors is capable of indicating the presence or absence of urine and at least one of the sensors is capable of indicating impending leakage of urine from the article.