Patents by Inventor Xun Liu

Xun Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200069800
    Abstract: The present invention provides a PD-L1 antibody pharmaceutical composition and use thereof. In particular, the present invention provides a pharmaceutical composition comprising the PD-L1 antibody or an antigen-binding fragment thereof in a succinate buffer. In addition, the pharmaceutical composition may also contain a sugar and a nonionic surfactant.
    Type: Application
    Filed: May 15, 2018
    Publication date: March 5, 2020
    Inventors: Zhen Yan, Jianjian Yang, Xiaodan Yan, Shan Wu, Xun Liu
  • Publication number: 20200030453
    Abstract: A method for preparing an antibody-drug conjugate (ADC). In particular, the method mainly utilizes a combination of antibody biomolecules and an ion exchange carrier through electrostatic interaction to realize solid phase preparation of an ADC drug. Elution conditions are optimized, to control a drug-to-antibody coupling ratio (DAR) and separate a polymer-coupled drug, reduce the amount of a drug used in a coupling reaction, and enhance the targeted therapeutic effect of an ADC drug. The preparation method features fewer steps, simple operation, and programmable control, facilitating industrial scale-up production, and also realizing zero retention of reducing agents and organic solvents in the preparation process, significantly improving drug safety and reducing production costs.
    Type: Application
    Filed: March 29, 2018
    Publication date: January 30, 2020
    Inventors: Yupeng Liu, Xiaofei Zhang, Zhi Liang, Ruijun Shi, Jin Zhong, Xun Liu, Weikang Tao, Lianshan Zhang, Piaoyang Sun
  • Publication number: 20190379240
    Abstract: A wireless power adapter uses a passive conversion circuit to convert an incompatible transmitter-receiver pair into a compatible transmitter-receiver pair. The wireless power adapter transfers power between a main transmitter and main receiver that are incompatible with each other. In one aspect, the wireless power adapter includes an auxiliary receiver coil system, a auxiliary transmitter coil system and a passive conversion circuit. The auxiliary receiver coil system is compatible with the main transmitter and can efficiently receive wireless power transmitted by the main transmitter that is external to the adapter. The auxiliary transmitter coil system is compatible with the main receiver and can produce wireless power to be efficiently transmitted to the main receiver. The passive conversion circuit connects the incompatible main transmitter and main receiver by transferring power from the auxiliary receiver coil system to the auxiliary transmitter coil system.
    Type: Application
    Filed: June 11, 2018
    Publication date: December 12, 2019
    Inventor: Xun Liu
  • Publication number: 20190370999
    Abstract: The present invention provides a method, a system and an equipment for automatically detecting and tracking a blade, used for tracking the blade of the wind power generator through an unmanned aerial vehicle. The unmanned aerial vehicle is provided with a cradle head, the cradle head controls a shooting angle of a camera, including the following steps: acquiring a blade video file through a camera, detecting at least one frame of the blade image in the blade video file, and extracting side edges of the blade region in the at least one frame of blade images; tracking and detecting the side edges of the blade region in temporally adjacent multi-frame blade images in the blade video file according to the side edges of the blade region; determining a center point of the blade region in each frame of the blade image; and adjusting the cradle head.
    Type: Application
    Filed: August 27, 2018
    Publication date: December 5, 2019
    Applicant: Shanghai Clobotics Technology Co., Ltd.
    Inventors: Xun LIU, Limin SHANG, Xiaoming CHEN, Hua YE, Yan KE
  • Publication number: 20190366088
    Abstract: The present disclosure discloses a deep brain stimulation system having k focuses, which comprises: a first electrode and a second electrode, used for connecting one side of a brain scalp; a third electrode and a fourth electrode, used for connecting the other side of the brain scalp; and a first signal generation unit, a second signal generation unit, . . . , a (2k?1)th signal generation unit and a 2kth signal generation unit, wherein the k is a positive integer greater than or equal to 2; and each of the signal generation units is used for providing the following currents for the first electrode to the fourth electrode: a first current and a second current, which are interfered at a deep portion of a brain to form a first focus; and a (2k?1)th current and a 2kth current, which are interfered at the deep portion of the brain to form a kth focus; for the first current, the second current, . . .
    Type: Application
    Filed: December 20, 2018
    Publication date: December 5, 2019
    Inventors: Jue WANG, Xiaoqi ZHU, Zi-Gang HUANG, Youjun LI, Liang ZHENG, Tian LIU, Bixin SHAO, Chenxi LI, Xun LIU, Ziwei Xu, Boya Xu
  • Patent number: 10418031
    Abstract: The present disclosure discloses a voice remote controller and a power supplying method thereof. The voice remote controller comprises: a noise gathering module for gathering ambient noise at the periphery of the voice remote controller by using a sound aperture array; a sound-electricity converting module for converting the ambient noise gathered by the noise gathering module into an electrical signal; and an energy storing module for storing the electrical signal converted by the sound-electricity converting module as electric energy and supplying power to the voice remote controller. According to the present disclosure, ambient noise is gathered by a sound aperture array and converted into electricity used as the working energy, thereby avoiding battery replacing or frequent charging. When a voice function of a voice remote controller is turned off, all of the gathered ambient noise is converted into electricity, thereby improving the energy utilization rate.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: September 17, 2019
    Assignee: Qingdao Goertek Technology Co., Ltd.
    Inventors: Xun Liu, Pengpeng Liu, Zhicheng Liu
  • Publication number: 20190213272
    Abstract: A method of operation of a navigation system includes: receiving a navigation external data including a vendor data, a delta data, or a combination thereof; generating a normalization data with a control unit based on transforming the navigation external data according to universal format; generating an aggregation changeset data by splitting the normalization data into each instance of a dimension type; and updating a navigation local data by applying the aggregation changeset data according to a layer prioritization for presenting the navigation local data on a device.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 11, 2019
    Inventors: Shannph Simon Wong, John Andrew Michael Novak, Harald Koertge, Stefan C. Karschti, Xun Liu, Vladimir Lemberg, Md Ahsan Habib
  • Publication number: 20190189716
    Abstract: A display apparatus, an electronic apparatus (4000), a method for treating failure of a light-emitting unit and an apparatus (7000) for treating failure of a light-emitting unit. The display apparatus comprises: a light-emitting device (10), comprising a plurality of light-emitting units (11) that form a matrix arrangement; and a light-transmitting device (20) provided over the light-emitting device (10), wherein the light-transmitting device (20) comprises a plurality of light-transmitting units (21) that form a matrix arrangement and are provided corresponding to the light-emitting units (11), each of the light-transmitting units (21) is of a rectangle shape, and comprises a light-transmitting opening (212) that is formed by enclosing of side walls (213) that have an independent inflating passageway (215), and the side walls (213) are configured to have a light refraction passageway (214).
    Type: Application
    Filed: December 31, 2016
    Publication date: June 20, 2019
    Inventors: Xun LIU, Maoqing TANG
  • Patent number: 10305332
    Abstract: Methods and systems are described for using detection coils to detect metallic or conductive foreign objects that can interfere with the wireless transfer of power from a power transmitter to a power receiver. In particular, the detection coils are targeted to foreign objects that are smaller than a power transmitter coil in the power transmitter.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: May 28, 2019
    Assignee: ConvenientPower HK Ltd.
    Inventors: Xun Liu, Laurens Henricus Swaans, Ka Wai Paul Chan, Ho Kan Low, Wing Kwong Chan
  • Publication number: 20190155536
    Abstract: According to various aspects of the present disclosure, methods, systems, and media for data migration are provided. In some embodiments, the systems may include: at least one computer-readable storage medium including a set of instructions for migrating data records; and at least one processor in communication with the computer-readable storage medium, wherein when executing the set of instructions, the at least one processor is directed to: query data in a data storage system comprising a plurality of slave nodes; determine, from a plurality of data records in the slave nodes, at least one candidate data record that satisfies a first condition; identify, from the slave nodes, at least one candidate slave node that satisfies a second condition; and in response to determining that the number of the at least one candidate slave node is not less than a threshold value, migrate the candidate data record to a target slave node.
    Type: Application
    Filed: January 19, 2019
    Publication date: May 23, 2019
    Applicant: ZHEJIANG DAHUA TECHNOLOGY CO., LTD.
    Inventors: Le HUANG, Xun LIU
  • Patent number: 10141346
    Abstract: The present invention discloses a thin film transistor, a liquid crystal display and the manufacturing method of a thin film transistor. The thin film transistor includes a substrate, a gate electrode formed on the surface of the substrate; a gate insulting layer covered on the gate electrode; a semiconductor layer disposed on the surface of the gate insulating layer and corresponding to the gate electrode; an etching stop layer covered the semiconductor layer and having a first through hole and a second through hole; a passivation layer covered the etching stop layer having a third through hole and a fourth through hole; a source electrode disposed on the passivation layer and connected to the semiconductor layer via the first and the third through hole; and a drain electrode disposed on the passivation layer and connected to the semiconductor layer via the second and the fourth through hole.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: November 27, 2018
    Assignee: Shenzhen China Star Optoelectronics Technology Co., Ltd
    Inventor: Xun Liu
  • Publication number: 20180331584
    Abstract: Methods and systems are described for using detection coils to detect metallic or conductive foreign objects that can interfere with the wireless transfer of power from a power transmitter to a power receiver. In particular, the detection coils are targeted to foreign objects that are smaller than a power transmitter coil in the power transmitter.
    Type: Application
    Filed: July 2, 2018
    Publication date: November 15, 2018
    Inventors: Xun Liu, Laurens Henricus Swaans, Ka Wai Paul Chan, Ho Kan Low, Wing Kwong Chan
  • Publication number: 20180293979
    Abstract: The present disclosure discloses a voice remote controller and a power supplying method thereof. The voice remote controller comprises: a noise gathering module for gathering ambient noise at the periphery of the voice remote controller by using a sound aperture array; a sound-electricity converting module for converting the ambient noise gathered by the noise gathering module into an electrical signal; and an energy storing module for storing the electrical signal converted by the sound-electricity converting module as electric energy and supplying power to the voice remote controller. According to the present disclosure, ambient noise is gathered by a sound aperture array and converted into electricity used as the working energy, thereby avoiding battery replacing or frequent charging. When a voice function of a voice remote controller is turned off, all of the gathered ambient noise is converted into electricity, thereby improving the energy utilization rate.
    Type: Application
    Filed: May 25, 2016
    Publication date: October 11, 2018
    Inventors: Xun Liu, Pengpeng Liu, Zhicheng Liu
  • Patent number: 10044233
    Abstract: Methods and systems are described for using detection coils to detect metallic or conductive foreign objects that can interfere with the wireless transfer of power from a power transmitter to a power receiver. In particular, the detection coils are targeted to foreign objects that are smaller than a power transmitter coil in the power transmitter.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: August 7, 2018
    Assignee: ConvenientPower HK Ltd.
    Inventors: Xun Liu, Laurens Henricus Swaans, Ka Wai Paul Chan, Ho Kan Low, Wing Kwong Chan
  • Publication number: 20180193019
    Abstract: A bidirectional reversible medical skin tension reducing closer is provided. The closer comprises a left substrate and a right substrate, both of which are configured to be horizontally and symmetrically arranged, a left pawl and a right pawl fixedly arranged on adjacent ends of the left and right substrates respectively, and a left rack and a right rack, one end of each of which is fixedly connected to the left and right pawls respectively in an up-down side-by-side arrangement. Ratchets on the left and right pawls tilt towards the left and right substrates respectively, and the other ends of the left and right racks pass through the space beneath the right and left pawls respectively and are engaged with ratchets provided on the bottom of the right and left pawls respectively. Adhesive layers for fixing the left and right substrates onto the surface of the skin are arranged on the bottom surfaces of the left and right substrates.
    Type: Application
    Filed: July 19, 2016
    Publication date: July 12, 2018
    Inventors: Shuai YANG, Tiangang ZHU, Yao LIU, Xun LIU, Xinqin ZHOU
  • Patent number: 9981338
    Abstract: A hybrid Friction Stir Welding approach and device for dissimilar materials joining employing Electro-Plastic Effect. The approach and device include an introduction of high density, short period current pulses into traditional friction stir welding process, which therefore can generate a localized softened zone in the workpiece during plastic stirring without significant additional temperature increase. This material softened zone is created by high density current pulses based on Electro-Plastic Effect and will move along with the friction stir welding tool. Smaller downward force, larger processing window and better joint quality for dissimilar materials are expected to be achieved through this hybrid welding technique.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: May 29, 2018
    Assignee: The Regents of The University of Michigan
    Inventors: Xun Liu, Shuhuai Lan, Jun Ni
  • Patent number: 9973239
    Abstract: The present invention provides a mobile device including: a power receiver for wirelessly coupling with a power transmitter to receive power wirelessly from the power transmitter; and a function that automatically initiates upon the power receiver wirelessly coupling with the power transmitter. Also provided is a transmitter apparatus including a power transmitter for wirelessly coupling with a power receiver in a mobile device to provide power wirelessly to the power receiver, wherein, upon the power receiver wirelessly coupling with the power transmitter, data is transferred between the power transmitter and the power receiver and a function of the mobile device automatically initiates. The mobile device and transmitter apparatus together form a system for operating the mobile device. Methods and computer-readable media storing executable application programs associated with the system are also provided.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: May 15, 2018
    Assignee: ConvenientPower HK Ltd.
    Inventors: Xun Liu, Emmanuel Girma
  • Publication number: 20180102380
    Abstract: The present invention discloses a thin film transistor, a liquid crystal display and the manufacturing method of a thin film transistor. The thin film transistor includes a substrate, a gate electrode formed on the surface of the substrate; a gate insulting layer covered on the gate electrode; a semiconductor layer disposed on the surface of the gate insulating layer and corresponding to the gate electrode; an etching stop layer covered the semiconductor layer and having a first through hole and a second through hole; a passivation layer covered the etching stop layer having a third through hole and a fourth through hole; a source electrode disposed on the passivation layer and connected to the semiconductor layer via the first and the third through hole; and a drain electrode disposed on the passivation layer and connected to the semiconductor layer via the second and the fourth through hole.
    Type: Application
    Filed: April 14, 2016
    Publication date: April 12, 2018
    Applicant: Shenzhen China Star Optoelectronics Technology Co. , Ltd.
    Inventor: Xun LIU
  • Publication number: 20180054091
    Abstract: Methods and systems are described for using detection coils to detect metallic or conductive foreign objects that can interfere with the wireless transfer of power from a power transmitter to a power receiver. In particular, the detection coils are targeted to foreign objects that are smaller than a power transmitter coil in the power transmitter.
    Type: Application
    Filed: October 30, 2017
    Publication date: February 22, 2018
    Inventors: Xun Liu, Laurens Henricus Swaans, Ka Wai Paul Chan, Ho Kan Low, Wing Kwong Chan
  • Patent number: 9825486
    Abstract: Methods and systems are described for using detection coils to detect metallic or conductive foreign objects that can interfere with the wireless transfer of power from a power transmitter to a power receiver. In particular, the detection coils are targeted to foreign objects that are smaller than a power transmitter coil in the power transmitter.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: November 21, 2017
    Assignee: ConvenientPower HK Ltd.
    Inventors: Xun Liu, Laurens Henricus Swaans, Ka Wai Paul Chan, Ho Kan Low, Wing Kwong Chan