Patents by Inventor Yael Webb

Yael Webb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140378437
    Abstract: The present invention relates to 1,4-benzothiazepine derivatives and their use to treat conditions, disorders and diseases associated with ryanodine receptors (RyRs) that regulate calcium channel functioning in cells. The invention also discloses pharmaceutical compositions comprising the compounds and uses thereof to treat diseases and conditions associated with RyRs, in particular cardiac, musculoskeletal and central nervous system (CNS) disorders.
    Type: Application
    Filed: September 3, 2014
    Publication date: December 25, 2014
    Inventors: JIAMING YAN, SANDRO BELVEDERE, YAEL WEBB, MARC BERTRAND, NICOLE VILLENEUVE
  • Patent number: 8853198
    Abstract: The present invention relates to 1,4-benzothiazepine derivatives and their use to treat conditions, disorders and diseases associated with ryanodine receptors (RyRs) that regulate calcium channel functioning in cells. The invention also discloses pharmaceutical compositions comprising the compounds and uses thereof to treat diseases and conditions associated with RyRs, in particular cardiac, musculoskeletal and central nervous system (CNS) disorders.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: October 7, 2014
    Assignees: Les Laboratoires Servier, ARMGO Pharma, Inc.
    Inventors: Jiaming Yan, Sandro Belvedere, Yael Webb, Marc Bertrand, Nicole Villeneuve
  • Publication number: 20140088171
    Abstract: The present invention relates to 1,4-benzothiazepine derivatives and their use to treat conditions, disorders and diseases associated with ryanodine receptors (RyRs) that regulate calcium channel functioning in cells. The invention also discloses pharmaceutical compositions comprising the compounds and uses thereof to treat diseases and conditions associated with RyRs, in particular cardiac, musculoskeletal and central nervous system (CNS) disorders.
    Type: Application
    Filed: November 11, 2013
    Publication date: March 27, 2014
    Applicants: ARMGO PHARMA, INC., LES LABORATOIRES SERVIER
    Inventors: JIAMING YAN, SANDRO BELVEDERE, YAEL WEBB, MARK BERTRAND, NICOLE VILLENEUVE
  • Publication number: 20130281512
    Abstract: The present invention relates to 1,4-benzothiazepine derivatives and their use to treat conditions, disorders and diseases associated with ryanodine receptors (RyRs) that regulate calcium channel functioning in cells. The invention also discloses pharmaceutical compositions comprising the compounds and uses thereof to treat diseases and conditions associated with RyRs, in particular cardiac, musculoskeletal and central nervous system (CNS) disorders.
    Type: Application
    Filed: April 18, 2013
    Publication date: October 24, 2013
    Applicants: ARMGO Pharma, Inc., LES LABORATOIRES SERVIER
    Inventors: Jiaming YAN, Sandro BELVEDERE, Yael WEBB, Mark BERTRAND, Nicole VILLENEUVE
  • Patent number: 6890954
    Abstract: The present invention provides a method of inhibiting Fyn/Lck fatty acylation and protein palmitoylation in a cell in an individual in need of such treatment comprising the step of administering to said individual a pharmacologically effective dose of 2-bromopalmitate. Also provided is a method of treating an individual having an autoimmune disease comprising the step of administering to said individual a pharmacologically effective dose of 2-bromopalmitate.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: May 10, 2005
    Inventors: Marilyn D. Resh, Yael Webb