Patents by Inventor Yaguo Zheng

Yaguo Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of the EGF-receptor tyrosine kinase and methods for their use
    Patent number: 6864286
    Abstract: Novel compounds and pharmaceutical compositions useful as EGFR tyrosine kinase inhibitors. Methods of the invention include administration of the EGFR TK inhibitors to treat diseases characterized by enhanced expression of EGF, including cancers, particularly breast cancer. Additionally, a homology model representing the structure of EGFR kinase domain is provided, which model is useful for the rationally design and screening of compounds predicted to bind favorably to EGFR and to inhibit EGFR TK.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: March 8, 2005
    Assignee: Parker Hughes Institute
    Inventors: Fatih M. Uckun, Yaguo Zheng, Sutapa Ghosh
  • Inhibitors of the EGF-receptor tyrosine kinase and methods for their use
    Publication number: 20020107284
    Abstract: Novel compounds and pharmaceutical compositions useful as EGFR tyrosine kinase inhibitors. Methods of the invention include administration of the EGFR TK inhibitors to treat diseases characterized by enhanced expression of EGF, including cancers, particularly breast cancer. Additionally, a homology model representing the structure of EGFR kinase domain is provided, which model is useful for the rationally design and screening of compounds predicted to bind favorably to EGFR and to inhibit EGFR TK.
    Type: Application
    Filed: September 6, 2001
    Publication date: August 8, 2002
    Applicant: Parker Hughes Institute
    Inventors: Fatih M. Uckun, Yaguo Zheng, Sutapa Ghosh
  • BTK inhibitors and methods for their identification and use
    Patent number: 6365626
    Abstract: The invention provides BTK inhibitors, methods for their identification and use, and pharmaceutical compositions comprising BTK inhibitors.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: April 2, 2002
    Assignee: Parker Hughes Institute
    Inventors: Fatih M. Uckun, Yaguo Zheng, Sutapa Ghosh
  • Inhibitors of the EGF-receptor tyrosine kinase and methods for their use
    Patent number: 6355678
    Abstract: Novel compounds and pharmaceutical compositions useful as EGFR tyrosine kinase inhibitors. Methods of the invention include administration of the EGFR TK inhibitors to treat diseases characterized by enhanced expression of EGF, including cancers, particularly breast cancer. Additionally, a homology model representing the structure of EGFR kinase domain is provided, which model is useful for the rationally design and screening of compounds predicted to bind favorably to EGFR and to inhibit EGFR TK.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: March 12, 2002
    Assignee: Parker Hughes Institute
    Inventors: Fatih M. Uckun, Yaguo Zheng, Sutapa Ghosh
  • BTK inhibitors and methods for their identification and use
    Patent number: 6303652
    Abstract: The invention provides BTK inhibitors, methods for their identification and use, and pharmaceutical compositions comprising BTK inhibitors.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: October 16, 2001
    Assignee: Hughes Institute
    Inventors: Fatih M. Uckun, Yaguo Zheng, Sutapa Ghosh
  • BTK inhibitors and methods for their identification and use
    Patent number: 6294575
    Abstract: The invention provides BTK inhibitors, methods for their identification and use, and pharmaceutical compositions comprising BTK inhibitors.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: September 25, 2001
    Assignee: Parker Hughes Institute
    Inventors: Fatih M. Uckun, Yaguo Zheng, Sutapa Ghosh
  • BTK inhibitors and methods for their identification and use
    Patent number: 6221900
    Abstract: The invention provides BTK inhibitors, methods for their identification and use, and pharmaceutical compositions comprising BTK inhibitors.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: April 24, 2001
    Assignee: Hughes Institute
    Inventors: Fatih M. Uckun, Yaguo Zheng, Sutapa Ghosh
  • BTK inhibitors and methods for their identification and use
    Patent number: 6160010
    Abstract: The invention provides BTK inhibitors, methods for their identification and use, and pharmaceutical compositions comprising BTK inhibitors.
    Type: Grant
    Filed: July 22, 1999
    Date of Patent: December 12, 2000
    Assignee: Parker Hughes Institute
    Inventors: Fatih M. Uckun, Yaguo Zheng, Sutapa Ghosh