Patents by Inventor Yajun Guo

Yajun Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cellular vaccines and immunotherapeutics and methods for their preparation
    Publication number: 20050136066
    Abstract: The present invention provides a method for enhancing the immunogenicity of weakly immunogenic or non-immunogenic cells, resulting in a cellular vaccine that can stimulate T cell activation, which in turn leads to an effective immune response. The cellular vaccines of the present invention are useful for the prevention and treatment of diseases which develop and/or persist by escaping the immune response triggered by T cell activation. Such diseases include, for example, all cancers, natural and induced immune deficiency states, and diseases caused by infections with a variety of pathogens.
    Type: Application
    Filed: September 10, 2004
    Publication date: June 23, 2005
    Inventor: Yajun Guo
  • Antibodies specific for cancer associated antigen SM5-1 and uses thereof
    Publication number: 20050031617
    Abstract: The invention concerns antibodies which is specific for SM5-1 antigen expressed in melanoma, breast cancer and hepatocellular carcinoma, and polynucleotides encoding the antibodies. The invention further concerns use of such antibodies and/or polynucleotides in diagnosing and treating malignancies.
    Type: Application
    Filed: November 26, 2003
    Publication date: February 10, 2005
    Inventors: Jing Ma, Yajun Guo
  • Preparation and application of anti-tumor bifunctional fusion proteins
    Publication number: 20040254108
    Abstract: Provided herein is a chimeric protein, which chimeric protein comprises a Flt3 ligand, or a biologically active fragment thereof, and a proteinuous or peptidyl tumoricidal agent, and uses thereof, particularly in the treatment of malignancy.
    Type: Application
    Filed: November 26, 2003
    Publication date: December 16, 2004
    Inventors: Jing Ma, Yajun Guo
  • Cellular vaccines and immunotherapeutics and methods for their preparation
    Patent number: 6805869
    Abstract: The present invention provides a method for enhancing the immunogenicity of weakly immunogenic or non-immunogenic cells, resulting in a cellular vaccine that can stimulate T cell activation, which in turn leads to an effective immune response. The cellular vaccines of the present invention are useful for the prevention and treatment of diseases which develop and/or persist by escaping the immune response triggered by T cell activation. Such diseases include, for example, all cancers, natural and induced immune deficiency states, and diseases caused by infections with a variety of pathogens.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: October 19, 2004
    Assignee: Shanghai CP Guojian Pharmaceutical Co., Ltd.
    Inventor: Yajun Guo
  • CELLULAR VACCINES AND IMMUNOTHERAPEUTICS AND METHODS FOR THEIR PREPARATION
    Publication number: 20020102278
    Abstract: The present invention provides a method for enhancing the immunogenicity of weakly immunogenic or non-immunogenic cells, resulting in a cellular vaccine that can stimulate T cell activation, which in turn leads to an effective immune response. The cellular vaccines of the present invention are useful for the prevention and treatment of diseases which develop and/or persist by escaping the immune response triggered by T cell activation. Such diseases include, for example, all cancers, natural and induced immune deficiency states, and diseases caused by infections with a variety of pathogens.
    Type: Application
    Filed: December 17, 1998
    Publication date: August 1, 2002
    Inventor: YAJUN GUO