Patents by Inventor Yan Cai

Yan Cai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140264030
    Abstract: A chip-scale, air-clad semiconductor pedestal waveguide can be used as a mid-infrared (mid-IR) sensor capable of in situ monitoring of organic solvents and other analytes. The sensor uses evanescent coupling from a silicon or germanium waveguide, which is highly transparent in the mid-IR portion of the electromagnetic spectrum (e.g., between ?=1.3 ?m and ?=6.5 ?m for silicon and ?=1.3 ?m and ?=12.0 ?m for germanium), to probe the absorption spectrum of the fluid surrounding the waveguide. Launching a mid-IR beam into the waveguide exposed to a particular analyte causes attenuation of the evanescent wave's spectral components due to absorption by carbon, oxygen, hydrogen, and/or nitrogen bonds in the surrounding fluid. Detecting these changes at the waveguide's output provides an indication of the type and concentration of one or more compounds in the surrounding fluid.
    Type: Application
    Filed: November 11, 2013
    Publication date: September 18, 2014
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: PAO TAI LIN, YAN CAI, ANURADHA MURTHY AGARWAL, LIONEL C. KIMERLING
  • Publication number: 20140254620
    Abstract: In a method of forming a photonic device, a first silicon electrode is formed, and then a germanium active layer is formed on the first silicon electrode while including n-type dopant atoms in the germanium layer, during formation of the layer, to produce a background electrical dopant concentration that is greater than an intrinsic dopant concentration of germanium. A second silicon electrode is then formed on a surface of the germanium active layer. The formed germanium active layer is doped with additional dopant for supporting an electrically-pumped guided mode as a laser gain medium with an electrically-activated n-type electrical dopant concentration that is greater than the background dopant concentration to overcome electrical losses of the photonic device.
    Type: Application
    Filed: March 1, 2012
    Publication date: September 11, 2014
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Jonathan T. Bessette, Yan Cai, Rodolfo E. Camacho-Aguilera, Jifeng Liu, Lionel Kimerling, Jurgen Michel
  • Publication number: 20140235200
    Abstract: A system and method provides seamless switchover of a user device (UE) between a mobile data network and a wireless network while providing policy and charging control (PCC) of the data session in the mobile data network. A mobile core network component is made ASF aware to process user data traffic related to an auto switching function (ASF) server from a UE client located on the UE using a special access point name (APN). The mobile core network component then uses a dedicated deep packet inspection (ASF DPI) for all data transfers to the special APN. The core network component is then able to process the UE data traffic seamlessly as the traffic is toggled between the ASF tunnel the WiFi tunnel. By monitoring the data traffic on the ASF tunnel, the core component (GGSN/PGW) is able to provide PCC for the data session.
    Type: Application
    Filed: March 9, 2013
    Publication date: August 21, 2014
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Yan Cai, Canio Cillis, Ting Ding, Ekkart Leschke, Biao Long
  • Patent number: 7579003
    Abstract: The present invention provides a combined vaccine that includes hepatitis B vaccine (HeVac) and Bacille Calmette-Guerin (BCG) for intracutaneous injection and the method of preparation of such vaccine. The combined vaccine changes the now used liquid agent of the HeVac into a cryoprotectant, thus improving the heat stability of the HBsAg. Because of the cryoprotectant in the combined vaccine, the heat stability of the HBsAg is improved, and the efficacy of the vaccine is only slightly decreased after 30 days at 37° C., and the decrease is lower than with the liquid agent of the HeVac. The present invention changes the newborn's inoculation from two injections into one to simultaneously obtain prophylaxis of hepatitis B and tuberculosis.
    Type: Grant
    Filed: May 26, 2004
    Date of Patent: August 25, 2009
    Assignee: Changchun Institute of Biological Products
    Inventors: Lijie Jin, Zhi Wang, Xiaolin Zhao, Lihua Yang, Wange Chen, Aidong Yu, Junye Sun, Fuxue Zou, Yanming Liu, Aihong Liu, Lihong Yu, Yan Cai, Manlun Yu, Yuwu Wang, Changjun Zhou, Tong Yang, Dejuan Li, Xuan Luo, Li Li
  • Publication number: 20080181948
    Abstract: The present invention features solid pharmaceutical dosage formulations comprising ritonavir. As a non-limiting example, a dosage form of the present invention comprises a solid dispersion or solid solution of ritonavir in a matrix, where the matrix comprises at least one water-soluble polymer, such as copovidone, and at least one surfactant, such as polyoxyl 40 hydrogenated castor oil or macrogolglycerol hydroxystearate. Preferably, the solid dispersion or solution does not include, or includes only an insignificant amount of, PEG.
    Type: Application
    Filed: November 14, 2007
    Publication date: July 31, 2008
    Applicant: Abbott Laboratories
    Inventors: Gunther Berndl, Joerg Rosenberg, Bernd Liepold, Katja Fastnacht, Tina Jung, Wolfgang Roth, Joerg Breitenbach, John Morris, Cheri E. Klein, Yan Cai, Laman Alani, Soumojeet Ghosh
  • Publication number: 20060257423
    Abstract: The present invention provides a combined vaccine that includes hepatitis B vaccine (HeVac) and Bacille Calmette-Guerin (BCG) for intracutaneous injection and the method of preparation of such vaccine. The combined vaccine changes the now used liquid agent of the HeVac into a cryoprotectant, thus improving the heat stability of the HBsAg. Because of the cryoprotectant in the combined vaccine, the heat stability of the HBsAg is improved, and the efficacy of the vaccine is only slightly decreased after 30 days at 37° C., and the decrease is lower than with the liquid agent of the HeVac. The present invention changes the newborn's inoculation from two injections into one to simultaneously obtain prophylaxis of hepatitis B and tuberculosis.
    Type: Application
    Filed: May 26, 2004
    Publication date: November 16, 2006
    Inventors: Lijie Jin, Zhi Wang, Xiaolin Zhao, Lihua Yang, Wange Chen, Aidong Yu, Junye Sun, Fuxue Zou, Yanming Liu, Aihong Liu, Lihong Yu, Yan Cai, Manlun Yu, Yuwu Wang, Changjun Zhou, Tong Yang, Dejuan Li, Xuan Luo, Li Li